TRİGEMİNAL TROFİK SENDROMUN NADİR BİR NEDENİ: İSKEMİK KRANİYAL

Abstract

Trigeminal trofik sendrom (TTS), trigeminal sinirin farklı nedenlere ortaya çıkan hasarı sonucu trigeminal anestezi, fasiyal parestezi ve yüzde ülsere lezyonlar ile karakterize nadir görülen bir hastalıktır. Ülserasyon en sık burun kanadında ve tek lezyon şeklinde görülmekte olup trigeminal sinir dermatomuna uyan bölgelerde çoklu ülsere lezyonlarla nadiren karşılaşılmaktadır. Burada iskemik kraniyal nöropati sonrası çoklu fasiyal ülserasyonlarla başvuran bir TTS olgusu sunulmaktadır.

Keywords

• fasiyal parestezi
• fasiyal ülser
• trigeminal trofik sendrom

A RARE CAUSE OF TRIGEMINAL THROPHIC SYNDROME: ISCHEMIC CRANIAL NEUROPATHY

Abstract

Trigeminal trophic syndrome (TTS) is a rare disease characterized by trigeminal anesthesia, facial paresthesia, and ulcerated lesions on the face as a result of damage to the trigeminal nerve due to different causes. Ulceration is most commonly seen as a single lesion on the nasal wing. Multiple ulcerated lesions are rarely encountered in the regions at trigeminal nerve dermatome. Here, a case of TTS presenting with multiple facial ulcerations after ischemic cranial neuropathy is reported.

Keywords

• facial paresthesias
• facial ulcer
• trigeminal trophic syndrome

References

1. 1. Khan AU, Khachemoune A. Trigeminal trophic syndrome: an updated review. Int J Dermatol. 2019;58(5):530-537.
2. 2. Dhali TK, Agrawal S. Postherpetic Trigeminal Trophic Syndrome: An under-recognized condition. Nepal Journal of Dermatology, Venereology & Leprology. 2010; 9(1): 31- 33.
3. 3. Fruhauf J, Schaider H, Massone C, Kerl H, Mullegger RR.Carbamazepine as the only effective treatment in a 52-year-old man with trigeminal trophic syndrome. Mayo Clin Proc. 2008;83(4):502-504.
4. 4. Monrad SU, Terrell JE, Aronoff DM. The trigeminal trophic syndrome: an unusual cause of nasal ulceration. J Am Acad Dermatol. 2004;50:949–52.
5. 5. Rashid RM, Khachemoune A. Trigeminal trophic syndrome. J Eur Acad Dermatol Venereol. 2007;21(6):725- 731.
6. 6. Luksić I, Luksić I, Sestan-Crnek S, et al. Trigeminal trophic syndrome of all three nerve branches: an underrecognized complication after brain surgery. J Neurosurg 2008; 108: 170–173.
7. 7. Sadeghi P and Papay FA. Trigeminal trophic syndrome- report of four cases and review of the literature. Dermatol Surg 2004; 30: 807–812.
8. 8. Bradburn KH, Elston D, Murphey AW, Patel KG. Trigeminal trophic syndrome-a unique clinical presentation of a rare condition. Ear Nose Throat J. 2019;98(10):606-8.

9. 9. Bhatti AF, Soggiu D and Orlando A. Trigeminal trophic syndrome: diagnosis and management difficulties. Plast Reconstr Surg 2008; 121(1): 1e–3e.
10. 10. Dolohanty LB, Richardson SJ, Herrmann DN, Markman J, Mercurio MG. Trigeminal trophic syndrome with histopathologic correlation. Cutis. 2015;95:E22-5.
11. 11. Curtis AR, Oaklander AL, Johnson A, Yosipovitch G. Trigeminal trophic syndrome from stroke: an under-recognized central neuropathic itch syndrome. Am J Clin Dermatol. 2012; 13(2):125–128. [PubMed: 22220970]
12. 12. Gambeta E, Chichorro JG, Zamponi GW. Trigeminal neuralgia: An overview from pathophysiology to pharmacological treatments. Mol Pain. 2020;16:1-18.
13. 13. Sawada T, Asai J, Nomiyama T, Masuda K, Takenaka H, Katoh N. Trigeminal trophic syndrome: report of a case and review of the published work. J Dermatol. 2014;41(6):525-8.
14. 14. Cruccu G, Finnerup NB, Jensen TS, Scholz J, Sindou M, Svens- son P et al. Trigeminal neuralgia: New classification and diagnostic grading for practice and research. 2016;87(2):220–228.