Retrospective Analysis of Nonadenocarcinoma Tumors Mimicking Colorectal Adenocarcinoma

Abstract

Objective: Adenocarcinoma is the most common pathology in patients operated on for colorectal tumor (CRT). Non-adenocarcinoma CRTs are rare and therefore data on non-adenocarcinoma CRT are limited. We aim to contribute to the literature by presenting data on non-adenocarcinoma CRT in our clinic. Methods: Patients who underwent elective surgery due to CRC in our clinic between 01.01.2010 and 01.01.2020 were retrospectively screened. Patients who were diagnosed histopathologically as non-adenocarcinoma tumor were recorded. Results: Eighteen patients (2.25%) with a pathological diagnosis other than adenocarcinoma among 798 patients who were operated electively for CRC were included in the study. Nine patients were female (50%) and the average age was 52.8 (33-70). The most common pathological diagnosis was neuroendocrine tumor in 7 patients (38.9%) and lymphoma in 4 patients (22.2%). Two patients (11.1%) had malignant melanoma and lipoma. Scwannoma, granular tumor, and endometriosis were other diagnoses. No mortality developed in the patients. Average hospital stay was 7.44 days (3-18). Tumors were most frequently localized to rectum (%33,3). In 12 patients (66.6%), 12 or more lymph nodes were excised. Surgical margins were safe in all patients. Preoperative histopathological diagnosis could only be made in 9 patients (50%). Conclusion: Non-adenocarcinoma CRC are rare tumors that are seen at younger ages than adenocarcinomas, do not have male dominance and have a low preoperative diagnosis rate. Colorectal surgeons should keep in mind non-adenocarcinoma tumors in tumoral masses with atypical features that cannot be diagnosed before surgery. Multidisciplinary approach is important in the diagnosis and treatment process.

Keywords

• colorectal cancer
• coloretal tumors
• adenocarcinoma
• neuroendocrine tumor
• colonic lymphoma

Kolorektal Adenokarsinomu Taklit Eden Nonadenokarsinom Tümörlerin Retrospektif Analizi

Abstract

Amaç: Kolorektal tümör (KRT) nedeniyle ameliyat edilen hastalarda en sık görülen patoloji adenokanserdir. Non-adenokarsinom KRT’ler nadirdir ve bu nedenle adenokarsinom dışı KRT’le ilgili veriler kısıtlıdır. Kliniğimizdeki nonadenokarsinom KRT’le ilgili verileri sunarak literatüre katkı sunmayı amaçlıyoruz. Yöntem: Kliniğimizde 01.01.2010 - 01.01.2020 tarihleri arasında KRT nedeniyle elektif olarak ameliyat edilen hastalar retrospektif olarak tarandı. Histopatolojik olarak adenokarsinom dışı tümör tanısı konan hastalar kaydedildi. Bulgular: KRT nedeniyle elektif olarak ameliyat edilen toplam 798 hasta arasından adenokarsinom dışı patolojik tanısı olan 18 hasta (%2,25) çalışmaya alındı. Dokuz hasta (%50) kadındı ve ortalama yaş 52,8’di (33-70). En sık patolojik tanı, 7 hastada (%38,9) nöroendokrin tümör ve 4 hastada (%22,2) lenfomaydı. İkişer hastada (%11,1) malign melanom ve lipom mevcuttu. Scwannoma, granüler tümör ve endometriozis diğer tanılardı. Hastalarda mortalite gelişmedi. Ortalama yatış süresi 7.44 gündü (3-18). Tümörler en sık rektuma (%33,3) lokalizeydi. On iki hastada (%66,6) 12 ve üzerinde lenf nodu eksize edildi. Tüm hastalarda cerrahi sınırlar salimdi. Ameliyat öncesi histopatolojik tanı sadece 9 hastaya (%50) konabildi. Sonuç: Nonadenokarsinom KRT’ler adenokarsinomlara göre daha genç yaşlarda görülen, erkek dominansı olmayan, ameliyat öncesi tanı oranı düşük nadir tümörlerdir. Kolorektal cerrahlar, ameliyat öncesi tanı konulamayan, atipik özellikleri olan tümöral kitlelerde adenokarsinom dışı tümörleri akılda tutmalıdır. Tanı ve tedavi sürecinde multidisipliner yaklaşım önemlidir.

Keywords

• kolorektal kanser
• kolorektal tümörler
• adenokarsinom
• nöroendokrin tümör
• kolonik lenfoma

Supporting Institution

yok

Thanks

Patoloji görselleri için S.B.Ü. Tepecik Eğitim ve Araştırma Hastanesi Patoloji Kliniği'nden Sayın Doç.Dr. Emel Ebru PALA'ya teşekkürlerimizi sunarız.

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