Genetic characterization of Iranian subpopulations using 15 forensic autosomal STR loci

Abstract

The objective of present study was to compare genetic structure of seven Iranian provinces and to understand the genetic relationship among these seven provinces (Isfahan, Fars, Hormozgan, Kerman, Chaharmahal & Bakhtiari, Kohgiluyeh & Boyer Ahmad, and Yazd). For this purpose, a set of 15 STR’s loci were investigated. This panel of STRs is standard forensic science genetic testing tool that we added some importance to them by putting them in genetic variation analysis. The results based upon Fisher exact test for Hardy-Weinberg equilibrium (HWE) indicated that the allele and genotype distributions were in accordance with HardyWeinberg expectations except for D16S539. From genetic diversity point of view, D2S1338 was among the best STR loci and Isfahan has the highest value in aspect of these indices. Our results indicated that high amount of gene flow have been from Isfahan to Fars, which should be further investigated. Also, we indirectly shown that those forensic motivated genetic markers could be used as reliable tool for genetic differentiation when sounds data are available. We did not mean to estimate forensic science specific measures e.g. probability match and etc. for current study. 

Keywords

• STR’s loci,genetic relationship,genetic diversity,Iranian population

References

1. Akbari MT, Papiha SS, Roberts DF, Farhud DD. (1986) Population genetics of the Persians and other peoples in Iran. Z Morphol Anthropol 76:197-217.