Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent

Volume: 2 Number: 4 December 1, 2005
  • Taofeeq Oduola
  • Ganiyu Oyebola Adeosun
  • Tesleem Aderemi Oduola
  • Godwin Ovie
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European Journal of General Medicine
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Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent

Abstract

Aim: Jatropha gossypifolia belongs to the family “Euphorbiacea”. The coagulant activity and the mechanism of action of Jatropha gossypifolia stem latex as a haemostatic agent were investigated. Methods: The mechanism of action was investigated using doubling dilution technique by mixing neat (undiluted) and serial dilutions of the latex with 30% bovine albumin. Results: The results of whole blood clotting time using Lee and White method and bleeding time using Ivy\'s method were significantly reduced (P < 0.05) when stem latex was introduced than when the tests were performed without stem latex. This means that the stem latex possesses procoagulant activity. Conclusion: The result of this test showed that precipitation of coagulant factors is the mechanism of action of its haemostatic activity. Keywords: Jatropha gossypifolia, haemostatic agent, mechanism.

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Primary Language

English

Subjects

-

Journal Section

-

Authors

Taofeeq Oduola This is me

Ganiyu Oyebola Adeosun This is me

Tesleem Aderemi Oduola This is me

Godwin Ovie This is me
Obafemi Awolowo University Teaching Hospital Complex, School of Medical Laboratory Sciences, Departments of Hematology1, Chemical Pathology2, Medicine3 and Histopathology4 Ile-Ife, Osun State, Nigeria

Publication Date

December 1, 2005

Submission Date

April 27, 2015

Acceptance Date

-

Published in Issue

Year 2005 Volume: 2 Number: 4

IZ

https://izlik.org/JA83AK87PN

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RIS / Bibtex
APA
Oduola, T., Adeosun, G. O., Oduola, T. A., & Ovie, G. (2005). Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine, 2(4), 140-143. https://izlik.org/JA83AK87PN
AMA
1.Oduola T, Adeosun GO, Oduola TA, Ovie G. Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine. 2005;2(4):140-143. https://izlik.org/JA83AK87PN
Chicago
Oduola, Taofeeq, Ganiyu Oyebola Adeosun, Tesleem Aderemi Oduola, and Godwin Ovie. 2005. “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”. European Journal of General Medicine 2 (4): 140-43. https://izlik.org/JA83AK87PN.
EndNote
Oduola T, Adeosun GO, Oduola TA, Ovie G (December 1, 2005) Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine 2 4 140–143.
IEEE
[1]T. Oduola, G. O. Adeosun, T. A. Oduola, and G. Ovie, “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”, European Journal of General Medicine, vol. 2, no. 4, pp. 140–143, Dec. 2005, [Online]. Available: https://izlik.org/JA83AK87PN
ISNAD
Oduola, Taofeeq - Adeosun, Ganiyu Oyebola - Oduola, Tesleem Aderemi - Ovie, Godwin. “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”. European Journal of General Medicine 2/4 (December 1, 2005): 140-143. https://izlik.org/JA83AK87PN.
JAMA
1.Oduola T, Adeosun GO, Oduola TA, Ovie G. Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine. 2005;2:140–143.
MLA
Oduola, Taofeeq, et al. “Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent”. European Journal of General Medicine, vol. 2, no. 4, Dec. 2005, pp. 140-3, https://izlik.org/JA83AK87PN.
Vancouver
1.Taofeeq Oduola, Ganiyu Oyebola Adeosun, Tesleem Aderemi Oduola, Godwin Ovie. Mechanism of Action of Jatropha Gossypifolia Stem Latex As a Haemostatic Agent. European Journal of General Medicine [Internet]. 2005 Dec. 1;2(4):140-3. Available from: https://izlik.org/JA83AK87PN