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Anesthetic Management of Gaucher Disease

Year 2013, Volume: 10 Issue: 3, - , 01.09.2013

Hasan Husnu Yuce Saban Yalcin Mehmet Vural Ahmet Kucuk Harun Aydogan Mahmut Alp Karahan

Abstract

Gaucher, the most common form of lysosomal storage diseases, is caused by an inherited deficiency of the beta-glucocerebrosidase enzyme. Gaucher disease may present a challenge to the anesthesiologist because of abnormal coagulation and multiorgan disease in obstetric situations. These factors may affect choice of anesthesia type. We aimed to report the diverse anesthetic management of Gaucher Disease depending on patient\'s characteristics in two different cases.

Keywords

Gaucher anesthesia obstetric thrombocytopenia

References

  • Jmoudiak M, Futerman AH. Gaucher disease: Pathological mechanisms and modern management. Br J Haematol 2005;129:178-88
  • Chen M, Wang J. Gaucher disease: Review of the litera- ture. Arch Pathol Lab Med 2008;132:851-3
  • Grabowski G: Recent clinical progress in Gaucher disease. Curr Opin Pediatr 2005;17:519-24
  • Beutler E, Gelbart T. Gaucher disease mutations in non- Jewish patients. Br J Haematol 1993 ;85:401–5
  • Ioscovich A, Elstein Y, Halpern S, Vatashsky E, Grisaru- Granovsky S, Elstein D. Anesthesia for obstetric patients with Gaucher disease: survey and review. Int J Obstet Anesth 2004 ;13:244-50
  • Dell’Oste C, Vicenti F. Anesthetic management of chil- dren with type II and III Gaucher disease. Minerva Pediatr 1997; 49: 495–8
  • Tobias JD, Atwood R, Lowe S, Holcomb GW, 3rd. Anesthetic considerations in the child with Gaucher disease. J Clin Anesth 1993; 5: 150–3
  • Cano Ruiz A, Martin Scarpa A, Montescillo Francia A, Moreno Caparros A. Gaucher’s disease type I. an infre- quent cause of portal hypertension. An Med Interna 1998; 15: 483–4
  • Gillis S, Hyam E, Abrahamov A, Elstein D, Zimran A. Platelet function abnormalities in Gaucher disease pa- tients. Am J Hematol 1999;61: 103–6
  • Ioscovich A, Briskin A, Lebel E, et al. Anaesthesia for total hip replacement in Gaucher's disease. Eur J Anaesthesiol. 2006;23:265-6
  • Gielchinsky Y, Elstein D, Hadas-Halpern I, Lahad A, Abrahamov A, Zimran A. Is there a correlation between degree of splenomegaly, symptoms and hypersplenism? A study of 218 patients with Gaucher disease. Br J Haematol 1999; 106: 812–6 183

Anesthetic Management of Gaucher Disease

Year 2013, Volume: 10 Issue: 3, - , 01.09.2013

Hasan Husnu Yuce Saban Yalcin Mehmet Vural Ahmet Kucuk Harun Aydogan Mahmut Alp Karahan

Abstract

Gaucher, lizozomal depo hastalıklarının en sık görülen formu olup, kalıtsal beta glukoserebrozidaz enzim eksikliği nedeni ile oluşur. Gaucher hastalığı, obstetrik durumlarda anormal koagülasyon ve çoklu organ tutulumu nedeniyle anestezistler için zorluk oluşturur. Bu faktörler anestezi türünün seçimini etkileyebilir. Bu olgu sunumunda iki olguda Gaucher hastalığında hastaların özelliklerine göre değişebilen farklı anestezik yaklaşımların bildirilmesini amaçladık

Keywords

Gaucher anestezi obstetrik trombositopeni

References

  • Jmoudiak M, Futerman AH. Gaucher disease: Pathological mechanisms and modern management. Br J Haematol 2005;129:178-88
  • Chen M, Wang J. Gaucher disease: Review of the litera- ture. Arch Pathol Lab Med 2008;132:851-3
  • Grabowski G: Recent clinical progress in Gaucher disease. Curr Opin Pediatr 2005;17:519-24
  • Beutler E, Gelbart T. Gaucher disease mutations in non- Jewish patients. Br J Haematol 1993 ;85:401–5
  • Ioscovich A, Elstein Y, Halpern S, Vatashsky E, Grisaru- Granovsky S, Elstein D. Anesthesia for obstetric patients with Gaucher disease: survey and review. Int J Obstet Anesth 2004 ;13:244-50
  • Dell’Oste C, Vicenti F. Anesthetic management of chil- dren with type II and III Gaucher disease. Minerva Pediatr 1997; 49: 495–8
  • Tobias JD, Atwood R, Lowe S, Holcomb GW, 3rd. Anesthetic considerations in the child with Gaucher disease. J Clin Anesth 1993; 5: 150–3
  • Cano Ruiz A, Martin Scarpa A, Montescillo Francia A, Moreno Caparros A. Gaucher’s disease type I. an infre- quent cause of portal hypertension. An Med Interna 1998; 15: 483–4
  • Gillis S, Hyam E, Abrahamov A, Elstein D, Zimran A. Platelet function abnormalities in Gaucher disease pa- tients. Am J Hematol 1999;61: 103–6
  • Ioscovich A, Briskin A, Lebel E, et al. Anaesthesia for total hip replacement in Gaucher's disease. Eur J Anaesthesiol. 2006;23:265-6
  • Gielchinsky Y, Elstein D, Hadas-Halpern I, Lahad A, Abrahamov A, Zimran A. Is there a correlation between degree of splenomegaly, symptoms and hypersplenism? A study of 218 patients with Gaucher disease. Br J Haematol 1999; 106: 812–6 183
There are 11 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Hasan Husnu Yuce This is me

Saban Yalcin This is me

Mehmet Vural This is me

Ahmet Kucuk This is me

Harun Aydogan This is me

Mahmut Alp Karahan This is me

Publication Date September 1, 2013
Published in Issue Year 2013 Volume: 10 Issue: 3

Cite

APA Yuce, H. H., Yalcin, S., Vural, M., Kucuk, A., et al. (2013). Anesthetic Management of Gaucher Disease. European Journal of General Medicine, 10(3).
AMA Yuce HH, Yalcin S, Vural M, Kucuk A, Aydogan H, Karahan MA. Anesthetic Management of Gaucher Disease. European Journal of General Medicine. September 2013;10(3).
Chicago Yuce, Hasan Husnu, Saban Yalcin, Mehmet Vural, Ahmet Kucuk, Harun Aydogan, and Mahmut Alp Karahan. “Anesthetic Management of Gaucher Disease”. European Journal of General Medicine 10, no. 3 (September 2013).
EndNote Yuce HH, Yalcin S, Vural M, Kucuk A, Aydogan H, Karahan MA (September 1, 2013) Anesthetic Management of Gaucher Disease. European Journal of General Medicine 10 3
IEEE H. H. Yuce, S. Yalcin, M. Vural, A. Kucuk, H. Aydogan, and M. A. Karahan, “Anesthetic Management of Gaucher Disease”, European Journal of General Medicine, vol. 10, no. 3, 2013.
ISNAD Yuce, Hasan Husnu et al. “Anesthetic Management of Gaucher Disease”. European Journal of General Medicine 10/3 (September 2013).
JAMA Yuce HH, Yalcin S, Vural M, Kucuk A, Aydogan H, Karahan MA. Anesthetic Management of Gaucher Disease. European Journal of General Medicine. 2013;10.
MLA Yuce, Hasan Husnu et al. “Anesthetic Management of Gaucher Disease”. European Journal of General Medicine, vol. 10, no. 3, 2013.
Vancouver Yuce HH, Yalcin S, Vural M, Kucuk A, Aydogan H, Karahan MA. Anesthetic Management of Gaucher Disease. European Journal of General Medicine. 2013;10(3).