Severe hypokalemia-associated rhabdomyolise and unusual poliuria in patient with primary aldosteronism: A case presentation
Abstract
Primary aldosteronism is a syndrome that is characterized with hypertension, hypopotasemia, high level of plasma aldosterone, and low plasma renin activity. The case we present is a 56-year-old male who referred to our neurology clinic with proximal muscle weakness and fatigue. Because of uncontrolled blood pressure, a cardiology consultation was performed for the planning of antihypertensive treatment. As prolonged QT intervals and giant U waves due to serious hypokalemia (K+:1,04), cardiology clinic took over the patient for risks of arrhythmia. After primary hyperaldosteronism diagnosis was established, the treatment was initiated and severe polyuria developed during the treatment (19L/day). Key words: Primary aldosteronism, secondary hypertension, rhabdomyolysis, polyuria, hypokalemia
Keywords
References
- Conn JW. Presidential address. Part II. Primary aldoste- ronism, a new clinical syndrome, J Lab Clin Med 1955; 45:3–17.
- Streeten DHP, Tomycz N, Anderson GH. Reliability of screening methods for the diagnosis of primary aldoste- ronism. Am J Med 1979;67:403-13.
- Russell RP, Masi AT, Richter ED. Adrenal cortical adeno- mas and hypertension: a clinical pathologic analysis of 690 cases with matched controls and a review of the lit- erature. Medicine (Baltimore) 1972;51:211-25.
- Weinberger MH, Grim CE, Hollifield JW, Kem DC, Ganguly A, Kramer NJ, et al. Primary aldosteronism:diagnosis, lo- calization, and treatment. Ann Intern Med 1979;90:386- 95.
- Shenker Y. Medical treatment of low-renin aldosteronism. Endocrinol Metab Clin North Am 1989;18:415-42.
- Vallotton MB. Primary aldosteronism. II. Differential di- agnosis of hyperaldosteronism and pseudoaldosteronism. Clin Endocrinol 1996;45:53-60.
- Cain JP, Tuck ML, Williams GH, Dluhy RG, Rosenoff SH. The regulation of aldosterone secretion in primary aldo- steronism. Am J Med 1972;53:627-37.
- Ma JT, Wang C, Lam KS, Yeung RT, Chan FL, Boey J, et al. Fifty cases of primary hyperaldosteronism in Hong Kong Chinese with a high frequency of periodic paralysis. Evaluation of techniques for tumour localisation. QJ Med 1986;61:1021-37.
- Biglieri EG, Kater C. Primary mineralocorticoid excess in Greenspan FS (ed): Endocrinology, Connecticut: Appleton and Lange, 1991, p 365-371.
- Ömer Toprak, Atilla Üzüm, Rıfkı Ersoy, Mustafa Cirit. Hipocalsemia induced rhabdomyolysis and acute renal failure after thyroidectomy: A case report. Eur J Gen Med 2005;2(2):76-9.
- Mustafa Altay, Murat Duranay, Mevlüt Ceri, İlhan Kurultak, Fatma Aybala Altay. Severe Rhabdomyolysis secondary to serious hypernatremia. Eur J Gen Med 2007;4(2):98-9.
- Berl T, Linas SL, Aisenbrey GA, Anderson RJ. On the mech- anism of polyuria in potassium depletion. The role of polydipsia J Clin Invest 1977;60:620-5.
- Ganguly A. Prımary aldosteronısm New Engl J Med 1998; 339;828-33.
Severe hypokalemia-associated rhabdomyolise and unusual poliuria in patient with primary aldosteronism: A case presentation
Abstract
-
Keywords
References
- Conn JW. Presidential address. Part II. Primary aldoste- ronism, a new clinical syndrome, J Lab Clin Med 1955; 45:3–17.
- Streeten DHP, Tomycz N, Anderson GH. Reliability of screening methods for the diagnosis of primary aldoste- ronism. Am J Med 1979;67:403-13.
- Russell RP, Masi AT, Richter ED. Adrenal cortical adeno- mas and hypertension: a clinical pathologic analysis of 690 cases with matched controls and a review of the lit- erature. Medicine (Baltimore) 1972;51:211-25.
- Weinberger MH, Grim CE, Hollifield JW, Kem DC, Ganguly A, Kramer NJ, et al. Primary aldosteronism:diagnosis, lo- calization, and treatment. Ann Intern Med 1979;90:386- 95.
- Shenker Y. Medical treatment of low-renin aldosteronism. Endocrinol Metab Clin North Am 1989;18:415-42.
- Vallotton MB. Primary aldosteronism. II. Differential di- agnosis of hyperaldosteronism and pseudoaldosteronism. Clin Endocrinol 1996;45:53-60.
- Cain JP, Tuck ML, Williams GH, Dluhy RG, Rosenoff SH. The regulation of aldosterone secretion in primary aldo- steronism. Am J Med 1972;53:627-37.
- Ma JT, Wang C, Lam KS, Yeung RT, Chan FL, Boey J, et al. Fifty cases of primary hyperaldosteronism in Hong Kong Chinese with a high frequency of periodic paralysis. Evaluation of techniques for tumour localisation. QJ Med 1986;61:1021-37.
- Biglieri EG, Kater C. Primary mineralocorticoid excess in Greenspan FS (ed): Endocrinology, Connecticut: Appleton and Lange, 1991, p 365-371.
- Ömer Toprak, Atilla Üzüm, Rıfkı Ersoy, Mustafa Cirit. Hipocalsemia induced rhabdomyolysis and acute renal failure after thyroidectomy: A case report. Eur J Gen Med 2005;2(2):76-9.
- Mustafa Altay, Murat Duranay, Mevlüt Ceri, İlhan Kurultak, Fatma Aybala Altay. Severe Rhabdomyolysis secondary to serious hypernatremia. Eur J Gen Med 2007;4(2):98-9.
- Berl T, Linas SL, Aisenbrey GA, Anderson RJ. On the mech- anism of polyuria in potassium depletion. The role of polydipsia J Clin Invest 1977;60:620-5.
- Ganguly A. Prımary aldosteronısm New Engl J Med 1998; 339;828-33.
There are 13 citations in total.
Details
| Primary Language | English |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | September 1, 2012 |
| Published in Issue | Year 2012 Volume: 9 Issue: 3 |