Year 2007,
Volume: 4 Issue: 4, 176 - 179, 01.12.2007
Abstract
-
Keywords
References
- Gürkan E, Öndersev DV, Ulusoylu M, Göztaş Z, Dinçşahin N. Fitoterapi. Istanbul-Turkey, Marmara University Press , 2003, pp: 28, 38, 74.
- Cum G, Kunkar C Kunkar A. Supercritical CO2 extraction of Citrus Bergamia Risso oil. Proceedings of the 9th Smposium on Plant Originated Crude Drugs, 16-9 May 1991, Eskişehir, Turkey
- Tisserand R. The Art of Aromatherapy. Chapter Ed: C.W. Daniel, Essex, 1977.
- Graham PH, Browne L, Cox H, Graham J. Inhalation aromatherapy during radiotherapy: results of a placebo- controlled double-blind randomized trial. J Clin Oncol 2003;21(12):2372-6
- Zacher KD, Ippen H. Contact dermatitis caused by bergamot oil. Derm Beruf Umwelt 1984;32(3):95-7
- Kaddu S, Kerl H, Wolf P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J Am Acad Dermatol 2001;45(3):458-61
- Weisenseel P, Woitalla S. Toxic mustard plaster dermatitis after application of bergamot oil. MMW Fortschr Med 2005;147(51- 52):53-5 and phototoxic
- Romano L, Battaglia F, Masucci L, Sanguinetti M, Posteraro B, Plotti G, Zanetti S, Fadda G. In vitro activity of bergamot natural essence and furocoumarin-free and distilled extracts, and their associations with boric acid, against clinical yeast isolates. J Antimic Chem 2005;55(1):110-4
- Sanguinetti M, Posteraro B, Romano L, Battaglia F, Lopizzo T, De Carolis E, Fadda G. In vitro activity of Citrus bergamia (bergamot) oil against clinical isolates of dermatophytes. J Antimicrob Chemother 2006 (In press)
- Fisher K, Phillips CA. The effect of lemon, orange and bergamot essential oils and their components on the survival of Campylobacter jejuni, Escherichia coli O157, Listeria monocytogenes, Bacillus cereus and Staphylococcus aureus in vitro and in food systems. J Appl Microbiol. 2006;101(6):1232-40
- Peana AT, D’Aquila PS, Panin F, Serra G, Pippia P, Moretti MD. Anti- inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine 2002;9(8):721-6
- Özbek H, Sever B. Investigation of lethal doses and anti-inflammatory effect of Alpha-pinene on mice and rats. Turkish Pharmacological Society 18th National Pharmacology 2005, Izmir-Turkey, P-118 September
- Sever B, Özbek H. Investigation of lethal doses and anti-inflammatory effect of Alpha-pinene on mice and rats. Turkish Pharmacological Society 18th National Pharmacology 2005, Izmir-Turkey, P-72 September
- Winter CA, Risley EA, Nuss GW. Carragenin-induced edema in hind paw of the rats as an assay for antiinflammatory drugs. Proc Soc Exp Biol Med 1962;111: 544-7
- Rimbau V, Cerdan C, Vila R. Antiinflammatory activity of some extracts from plants used in the traditional medicine of North-African countries (II). Phytother Res 1999;13:128-32
- Kouadio F, Kanko C, Juge M, Grimaud N, Jean A, Guessan YTN, Petit JY. Analgesic and antiinflammatory activities of an extract from Parkia biglobosa used in traditional medicine in the Ivory Coast. Phytother Res 2000;14:635-7
Year 2007,
Volume: 4 Issue: 4, 176 - 179, 01.12.2007
Abstract
Aim: Essential oil of Bergamot (BO) was investigated for anti-inflammatory activity using carrageenan-induced rat paw oedema test. Methods: For the anti-inflammatory activity measurement six different groups were established and BO was administered in three different doses: 0.025, 0.05 and 0.10 mL/kg. Indomethacin was used as a reference agent. Results: It was found that reduction in the inflammation was 95.70% with indomethacin, 27.56% with 0.025 mL/kg BO, 30.77% with 0.05 mL/kg BO and 63.39% with 0.10 mL/kg BO. Indomethacin showed the strongest anti-inflammatory activity among the drugs used. The strongest anti-inflammatory activity of BO was seen with 0.10 mL/kg dosage. Median effective dose (ED50) value of BO was found to be 0.079 mL/kg. Conclusion: The results showed that BO posseses promising anti-inflammatory effect
Keywords
Citrus aurantium subsp. bergamia Bergamot oil anti-inflammatory activity carrageenan-oedema
References
- Gürkan E, Öndersev DV, Ulusoylu M, Göztaş Z, Dinçşahin N. Fitoterapi. Istanbul-Turkey, Marmara University Press , 2003, pp: 28, 38, 74.
- Cum G, Kunkar C Kunkar A. Supercritical CO2 extraction of Citrus Bergamia Risso oil. Proceedings of the 9th Smposium on Plant Originated Crude Drugs, 16-9 May 1991, Eskişehir, Turkey
- Tisserand R. The Art of Aromatherapy. Chapter Ed: C.W. Daniel, Essex, 1977.
- Graham PH, Browne L, Cox H, Graham J. Inhalation aromatherapy during radiotherapy: results of a placebo- controlled double-blind randomized trial. J Clin Oncol 2003;21(12):2372-6
- Zacher KD, Ippen H. Contact dermatitis caused by bergamot oil. Derm Beruf Umwelt 1984;32(3):95-7
- Kaddu S, Kerl H, Wolf P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J Am Acad Dermatol 2001;45(3):458-61
- Weisenseel P, Woitalla S. Toxic mustard plaster dermatitis after application of bergamot oil. MMW Fortschr Med 2005;147(51- 52):53-5 and phototoxic
- Romano L, Battaglia F, Masucci L, Sanguinetti M, Posteraro B, Plotti G, Zanetti S, Fadda G. In vitro activity of bergamot natural essence and furocoumarin-free and distilled extracts, and their associations with boric acid, against clinical yeast isolates. J Antimic Chem 2005;55(1):110-4
- Sanguinetti M, Posteraro B, Romano L, Battaglia F, Lopizzo T, De Carolis E, Fadda G. In vitro activity of Citrus bergamia (bergamot) oil against clinical isolates of dermatophytes. J Antimicrob Chemother 2006 (In press)
- Fisher K, Phillips CA. The effect of lemon, orange and bergamot essential oils and their components on the survival of Campylobacter jejuni, Escherichia coli O157, Listeria monocytogenes, Bacillus cereus and Staphylococcus aureus in vitro and in food systems. J Appl Microbiol. 2006;101(6):1232-40
- Peana AT, D’Aquila PS, Panin F, Serra G, Pippia P, Moretti MD. Anti- inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine 2002;9(8):721-6
- Özbek H, Sever B. Investigation of lethal doses and anti-inflammatory effect of Alpha-pinene on mice and rats. Turkish Pharmacological Society 18th National Pharmacology 2005, Izmir-Turkey, P-118 September
- Sever B, Özbek H. Investigation of lethal doses and anti-inflammatory effect of Alpha-pinene on mice and rats. Turkish Pharmacological Society 18th National Pharmacology 2005, Izmir-Turkey, P-72 September
- Winter CA, Risley EA, Nuss GW. Carragenin-induced edema in hind paw of the rats as an assay for antiinflammatory drugs. Proc Soc Exp Biol Med 1962;111: 544-7
- Rimbau V, Cerdan C, Vila R. Antiinflammatory activity of some extracts from plants used in the traditional medicine of North-African countries (II). Phytother Res 1999;13:128-32
- Kouadio F, Kanko C, Juge M, Grimaud N, Jean A, Guessan YTN, Petit JY. Analgesic and antiinflammatory activities of an extract from Parkia biglobosa used in traditional medicine in the Ivory Coast. Phytother Res 2000;14:635-7
There are 16 citations in total.
Details
| Primary Language | English |
|---|---|
| Journal Section | Original Articles |
| Authors | |
| Publication Date | December 1, 2007 |
| Published in Issue | Year 2007 Volume: 4 Issue: 4 |