Effect of extract of Pseudocedrela kotschyi on blood glucose conccentration of alloxan induced diabetic albino rats

Abstract

Abstract: The effect of extract of Pseudocedrela kotschi  on blood glucose of alloxan induced albino wistar rats was evaluated. Experimental animals received daily oral administration of extract of  P. kotschi for 14 days. The effect of 200mg/kg dose was studied during the treatment period. There was a significant reduction in blood glucose concentration (p< 0.05) with the mean blood glucose of the different groups having 5.5 + 0.33 for normal control, 7.0 + 0.40 for diabetic control group and 4.8 + 0.24 for diabetic treated group. The findings of this study suggest that extract of P. kotchi has hypoglycemic effect.

Key words : Pseudocedreala kotschi, hypoglycemia, diabetes, hyperglycemia

Keywords

• Pseudocedreala kotschi, hypoglycemia, diabetes, hyperglycemia

References

1. Dey L, Attele SA, Yuan CS. Alternative Therapies for Type 2 Diabetes. Alter Med Rev 2002; 7: 45- 58.
2. Haslett, C., Childers, E.R., Hunter, J.A., & Boon, N.A., (1999). Davidson Principles and Practice of Medicine. 18th Ed. N.Y. Churchill Livingstone.
3. Ononogbu, I.C., (1998). The role of lipid in the study and diagnosis of diabetes mellitus. Proceedings of the 1st African Conference on Biochemistry of Lipid. 1 : 57-69
4. Anuka, J.A. Ijezie, D.O., & Ezebnik, O.N. (1999). “Investigation of Pharmacological actions of the extract Pseudocedrela kotschyi in Laboratory animals. ABSTRACTS of the proceedings of XXVIIth Annual Regional Conference of WASP PP 9 – 10
5. Ghandi MSA. The antiinflammatory, analgesic and antipyrectic activity of Nigella Sativa. J Ethnopharmacol 2001; 76: 45-48.