Abstract. We presented four cases diagnosed with Herpes simplex virus encephalitis of those treated in our clinic in 2006 one of whom died, one recovered without any sequels. Two cases were left with advanced motor mental sequel. In this paper, clinical and laboratory findings along with diagnosis and treatment of Herpes simplex virus encephalitis were discussed.
Key words: Herpes Simplex virus, encephalitis, diagnosis and treatment
1. Eren SS, Öztoprak N, Çevik MA, et al. Herpes simplex ensefaliti: Bir olgu sunumu. Flora Derg 2005; 10: 148-150.
2. Mutluer N. Ensefalomyelitler ve Nöritler, Topçu AW, Söyletir G, Doğanay M (eds.) İnfeksiyon Hastalıkları ve Mikrobiyolojisi. 2nd ed. Nobel Tıp Kitapevleri, İstanbul 2002: 1019-1023.
3. Fleming DT, McQuillan GM, Johnson RE, et al. Herpes simplex virus type 2 in the United States, 1976 to 1994. NEJM 1997; 337: 1105-1111.
4. Schlitt M, Lakeman FD, Whitley RJ. Psychosis and herpes simplex encephalitis. South Med J 1985; 78: 1347-1350.
9. Avkan Oguz V, Yapar N, Sezak N, et al. Two cases of herpes encephalitis with normal cerebrospinal fluid findings. Mikrobiyol Bul 2006; 40: 93-98.
10. Sköldenberg B, Forsgren M, Alestig K, et al. Acyclovir versus vidarabine in herpes simplex encephalitis: Randomised multicenter study in consecutive Swedish patients. Lancet 1984; 2: 707- 711.
11. Shoji H. Japanese guidelines for the management of herpes simplex encephalitis; comparison with those from the International Management Herpes Forum. Rinsho Shinkeigaku 2006; 46: 955-957.
12. Whitley RJ, Alford CA, Hirsch MS, et al. Vidarabine versus acyclovir therapy in herpes simplex encephalitis. N Engl J Med 1986; 314: 144-149.
13. Dorsky DI, Crumpacker CS. Drugs five years later: Acyclovir. Ann Intern Med 1987; 107: 859-874.
14. Alp E, Yıldız O, Gökahmetoğlu S, et al. Herpes ensefalitinin erken tanısında moleküler ve görüntüleme yöntemlerinin önemi: bir olgu sunumu. Flora Derg 2005; 10: 145-147.
15. Ito S, Hirose Y, Mokuno K. The clinical usefulness of MRI diffusion weighted images in herpes simplex encephalitis-like cases. Rinsho Shinkeigaku 1999; 39: 1067-1070.
16. Wintergerst U, Belohradsky BH. Acyclovir monotherapy versus acyclovir plus beta-interferon in focal viral encephalitis in children. Infection 1992; 20: 207-212.
Year 2010,
Volume: 15 Issue: 1, 34 - 39, 15.01.2013
1. Eren SS, Öztoprak N, Çevik MA, et al. Herpes simplex ensefaliti: Bir olgu sunumu. Flora Derg 2005; 10: 148-150.
2. Mutluer N. Ensefalomyelitler ve Nöritler, Topçu AW, Söyletir G, Doğanay M (eds.) İnfeksiyon Hastalıkları ve Mikrobiyolojisi. 2nd ed. Nobel Tıp Kitapevleri, İstanbul 2002: 1019-1023.
3. Fleming DT, McQuillan GM, Johnson RE, et al. Herpes simplex virus type 2 in the United States, 1976 to 1994. NEJM 1997; 337: 1105-1111.
4. Schlitt M, Lakeman FD, Whitley RJ. Psychosis and herpes simplex encephalitis. South Med J 1985; 78: 1347-1350.
9. Avkan Oguz V, Yapar N, Sezak N, et al. Two cases of herpes encephalitis with normal cerebrospinal fluid findings. Mikrobiyol Bul 2006; 40: 93-98.
10. Sköldenberg B, Forsgren M, Alestig K, et al. Acyclovir versus vidarabine in herpes simplex encephalitis: Randomised multicenter study in consecutive Swedish patients. Lancet 1984; 2: 707- 711.
11. Shoji H. Japanese guidelines for the management of herpes simplex encephalitis; comparison with those from the International Management Herpes Forum. Rinsho Shinkeigaku 2006; 46: 955-957.
12. Whitley RJ, Alford CA, Hirsch MS, et al. Vidarabine versus acyclovir therapy in herpes simplex encephalitis. N Engl J Med 1986; 314: 144-149.
13. Dorsky DI, Crumpacker CS. Drugs five years later: Acyclovir. Ann Intern Med 1987; 107: 859-874.
14. Alp E, Yıldız O, Gökahmetoğlu S, et al. Herpes ensefalitinin erken tanısında moleküler ve görüntüleme yöntemlerinin önemi: bir olgu sunumu. Flora Derg 2005; 10: 145-147.
15. Ito S, Hirose Y, Mokuno K. The clinical usefulness of MRI diffusion weighted images in herpes simplex encephalitis-like cases. Rinsho Shinkeigaku 1999; 39: 1067-1070.
16. Wintergerst U, Belohradsky BH. Acyclovir monotherapy versus acyclovir plus beta-interferon in focal viral encephalitis in children. Infection 1992; 20: 207-212.
Karsen, H., Demir, C., Karahocagil, M. K., Sünnetcioğlu, M., et al. (2013). Herpes simplex encephalitis. EASTERN JOURNAL OF MEDICINE, 15(1), 34-39.
AMA
Karsen H, Demir C, Karahocagil MK, Sünnetcioğlu M, Akdeniz H. Herpes simplex encephalitis. EASTERN JOURNAL OF MEDICINE. March 2013;15(1):34-39.
Chicago
Karsen, Hasan, Cengiz Demir, Mustafa Kasım Karahocagil, Mahmut Sünnetcioğlu, and Hayrettin Akdeniz. “Herpes Simplex Encephalitis”. EASTERN JOURNAL OF MEDICINE 15, no. 1 (March 2013): 34-39.
EndNote
Karsen H, Demir C, Karahocagil MK, Sünnetcioğlu M, Akdeniz H (March 1, 2013) Herpes simplex encephalitis. EASTERN JOURNAL OF MEDICINE 15 1 34–39.
IEEE
H. Karsen, C. Demir, M. K. Karahocagil, M. Sünnetcioğlu, and H. Akdeniz, “Herpes simplex encephalitis”, EASTERN JOURNAL OF MEDICINE, vol. 15, no. 1, pp. 34–39, 2013.
ISNAD
Karsen, Hasan et al. “Herpes Simplex Encephalitis”. EASTERN JOURNAL OF MEDICINE 15/1 (March 2013), 34-39.
JAMA
Karsen H, Demir C, Karahocagil MK, Sünnetcioğlu M, Akdeniz H. Herpes simplex encephalitis. EASTERN JOURNAL OF MEDICINE. 2013;15:34–39.
MLA
Karsen, Hasan et al. “Herpes Simplex Encephalitis”. EASTERN JOURNAL OF MEDICINE, vol. 15, no. 1, 2013, pp. 34-39.
Vancouver
Karsen H, Demir C, Karahocagil MK, Sünnetcioğlu M, Akdeniz H. Herpes simplex encephalitis. EASTERN JOURNAL OF MEDICINE. 2013;15(1):34-9.