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HIV risk behavior and acceptability of microbicides in chennai, India

Year 2011, Volume: 16 Issue: 2, 160 - 167, 21.01.2013

Abstract

Abstract. To determine and compare the HIV/STI risk perceptions and behavior among men and women with traditionally high-risk and low-risk behavior in Chennai, India. To explore knowledge of HIV and Sexually transmitted infections (STI) and interest in and acceptability of potential microbicides and their characteristics in various subgroups. A cross-sectional survey investigating HIV knowledge, risk behavior and microbicide acceptability was conducted among 2072 participants. Participants were recruited from five target populations traditionally viewed as high- and low-risk: truck drivers, STI clinic patients, sex workers, married monogamous women, and the general population. Most participants were aware of HIV and its transmission routes, though many participants who engaged in risk behavior did not perceive themselves to be at risk for infection.  Overall interest in microbicides was high. Most female participants reported willingness to use a microbicide to prevent HIV/STI transmission, but not pregnancy. Men were willing to let other sexual partners, but not primary partners, use microbicides to prevent HIV/STI.  HIV/STI risk is high in men and women with high risk behavior as well as those generally considered low risk.  Risk perceptions and condom use reflect concordance only in high-risk women.  Interventions should be tailored to different subgroups of the population to improve accurate perceptions of risk while decreasing risky behaviors and promoting use of prevention methods and women’s ability to negotiate their use.  Microbicides were acceptable in some situations, but not others.  Microbicides should come in multiple formulations with and without contraceptive properties and interventions should target increasing acceptability within primary partnerships.  

Key words: HIV risk behavior, microbicide, India

References

  • 1. National AIDS Control Organization, Ministry of Health and Family Welfare, Government of India. http://www.naco.nic.in/. New Delhi, India.
  • 2. AIDS Epidemic Update 2007. Follow-up to the 2001 United Nations General Assembly Special Session on HIV/AIDS. Geneva: © Joint United Nations Programme on HIV/AIDS (UNAIDS) and World Health Organization (WHO) 2007.
  • 3. Solomon S, Kumarasamy N, Ganesh AK, Amalraj RE. Prevalence and risk factors of HIV-1 and HIV- 2 infection in urban and rural areas in Tamil Nadu, India. Int J STD AIDS 1998; 9: 98-103.
  • 4. Gangakhedkar RR, Bentley ME, Divekar AD, et al. Spread of HIV infection in married monogamous women in India. JAMA 1997; 278: 2090-2092.
  • 5. Ramjee G, Karim SS, Sturm AW. Sexually transmitted infections among sex workers in KwaZulu-Natal, South Africa. Sex Transm Dis 1998; 25: 346-349.
  • 6. Kilmarx PH, Limpakarnjanarat K, Mastro TD, et al. HIV-1 seroconversion in a prospective study of female sex workers in northern Thailand: continued high incidence among brothel-based women. AIDS 1998; 12: 1889-1898.
  • 7. Pais P. HIV and India: looking into the abyss. Trop Med Int Health 1996; 1: 295-304.
  • 8. Rodrigues JJ, Mehendale SM, Shepherd ME, et al. Risk factors for HIV infection in people attending clinics for sexually transmitted diseases in India. BMJ 1995; 311: 283-286.
  • 9. Elias CJ, Heise LL. Challenges for the development of female-controlled vaginal microbicides. AIDS 1994; 8: 1-9.
  • 10. Elias CJ, Coggins C. Female-controlled methods to prevent sexual transmission of HIV. AIDS 1996; 10: 43-51.
  • 11. Newmann S, Sarin P, Kumarasamy N, et al. Marriage, monogamy and HIV: a profile of HIVinfected women in south India. Int J STD AIDS 2000; 11: 250-253.
  • 12. Sobo EJ. Choosing unsafe sex: AIDS-risk denial among disadvantaged women. Philadelphia: University of Pennsylvania Press, 1995.
  • 13. Bollinger RC, Tripathy SP, Quinn TC. The human immunodeficiency virus epidemic in India. Current magnitude and future projections. Medicine (Baltimore) 1995; 74: 97-106.
  • 14. Gawande AV, Vasudeo ND, Zodpey SP, Khandait DW. Sexually transmitted infections in long distance truck drivers. J Commun Dis 2000; 32: 212-215.
  • 15. Mayer KH, Karim SA, Kelly C, et al. Safety and tolerability of vaginal PRO 2000 gel in sexually active HIV-uninfected and abstinent HIV-infected women. AIDS 2003; 17: 321-329.
  • 16. Bax R, Douville K, McCormick D, et al. Microbicides--evaluating multiple formulations of C31G. Contraception 2002; 66: 365-368.
  • 17. Harrison PF, Rosenberg Z, Bowcut J. Topical microbicides for disease prevention: status and challenges. Clin Infect Dis 2003; 36: 1290-1294.
  • 18. Johnston R. Microbicides 2002: an update. AIDS Patient Care STDS 2002; 16: 419-430.
  • 19. Bentley ME, Morrow KM, Fullem A, et al. Acceptability of a novel vaginal microbicide during a safety trial among low-risk women. Fam Plann Perspect 2000; 32: 184-188.
  • 20. Morrow K, Rosen R, Richter L, et al. The acceptability of an investigational vaginal microbicide, PRO 2000 Gel, among women in a phase I clinical trial. J Womens Health (Larchmt) 2003; 12: 655-666.
  • 21. Ganguli SK, Rekha PP, Gupte N, Charan UA. AIDS awareness among undergraduate students, Maharashtra. Indian J Public Health 2002; 46: 8- 12.
  • 22. Singh MB, Chaudhary RC, Haldiya KR. Knowledge and attitudes of pregnant women regarding AIDS in a semi arid area of Rajasthan. J Commun Dis 1997; 29: 139-144.
  • 23. Singh S, Fukuda H, Ingle GK, Tatara K. Knowledge, attitude, the perceived risks of infection and sources of information.
  • 24. about HIV/AIDS among pregnant women in an urban population of Delhi. J Commun Dis 2002; 34: 23-34.
  • 25. Kotwal A, Priya R, Thakur R, et al. Injection practices in a metropolis of North India: perceptions, determinants and issues of safety. Indian J Med Sci 2004; 58: 334-344.
  • 26. Gisselquist DP. Estimating HIV-1 transmission efficiency through unsafe medical injections. Int J STD AIDS 2002; 13: 152-159.
  • 27. Dhingra-Kumar N, Sharma AK, Madan N. Analysis of quality assurance programmes for HIV screening in blood transfusion centres in Delhi. Bull World Health Organ 1997; 75: 223-228.
  • 28. Chandiramani R. A view from the field: phone help line in India helps indentify HIV risk behaviors. SIECUS Rep 1998; 26: 4-6.
  • 29. Roth J, Krishnan SP, Bunch E. Barriers to condom use: results from a study in Mumbai (Bombay), India. AIDS Educ Prev 2001; 13: 65-77.
  • 30. Agarwal N, Deka D, Takkar D. Contraceptive status and sexual behavior in women over 35 years of age in India. Adv Contracept 1999; 15: 235-244.
  • 31. Baveja R, Buckshee K, Das K, et al. Evaluating contraceptive choice through the method-mix approach. An Indian Council of Medical Research (ICMR) task force study. Contraception 2000; 61: 113-119.
Year 2011, Volume: 16 Issue: 2, 160 - 167, 21.01.2013

Abstract

References

  • 1. National AIDS Control Organization, Ministry of Health and Family Welfare, Government of India. http://www.naco.nic.in/. New Delhi, India.
  • 2. AIDS Epidemic Update 2007. Follow-up to the 2001 United Nations General Assembly Special Session on HIV/AIDS. Geneva: © Joint United Nations Programme on HIV/AIDS (UNAIDS) and World Health Organization (WHO) 2007.
  • 3. Solomon S, Kumarasamy N, Ganesh AK, Amalraj RE. Prevalence and risk factors of HIV-1 and HIV- 2 infection in urban and rural areas in Tamil Nadu, India. Int J STD AIDS 1998; 9: 98-103.
  • 4. Gangakhedkar RR, Bentley ME, Divekar AD, et al. Spread of HIV infection in married monogamous women in India. JAMA 1997; 278: 2090-2092.
  • 5. Ramjee G, Karim SS, Sturm AW. Sexually transmitted infections among sex workers in KwaZulu-Natal, South Africa. Sex Transm Dis 1998; 25: 346-349.
  • 6. Kilmarx PH, Limpakarnjanarat K, Mastro TD, et al. HIV-1 seroconversion in a prospective study of female sex workers in northern Thailand: continued high incidence among brothel-based women. AIDS 1998; 12: 1889-1898.
  • 7. Pais P. HIV and India: looking into the abyss. Trop Med Int Health 1996; 1: 295-304.
  • 8. Rodrigues JJ, Mehendale SM, Shepherd ME, et al. Risk factors for HIV infection in people attending clinics for sexually transmitted diseases in India. BMJ 1995; 311: 283-286.
  • 9. Elias CJ, Heise LL. Challenges for the development of female-controlled vaginal microbicides. AIDS 1994; 8: 1-9.
  • 10. Elias CJ, Coggins C. Female-controlled methods to prevent sexual transmission of HIV. AIDS 1996; 10: 43-51.
  • 11. Newmann S, Sarin P, Kumarasamy N, et al. Marriage, monogamy and HIV: a profile of HIVinfected women in south India. Int J STD AIDS 2000; 11: 250-253.
  • 12. Sobo EJ. Choosing unsafe sex: AIDS-risk denial among disadvantaged women. Philadelphia: University of Pennsylvania Press, 1995.
  • 13. Bollinger RC, Tripathy SP, Quinn TC. The human immunodeficiency virus epidemic in India. Current magnitude and future projections. Medicine (Baltimore) 1995; 74: 97-106.
  • 14. Gawande AV, Vasudeo ND, Zodpey SP, Khandait DW. Sexually transmitted infections in long distance truck drivers. J Commun Dis 2000; 32: 212-215.
  • 15. Mayer KH, Karim SA, Kelly C, et al. Safety and tolerability of vaginal PRO 2000 gel in sexually active HIV-uninfected and abstinent HIV-infected women. AIDS 2003; 17: 321-329.
  • 16. Bax R, Douville K, McCormick D, et al. Microbicides--evaluating multiple formulations of C31G. Contraception 2002; 66: 365-368.
  • 17. Harrison PF, Rosenberg Z, Bowcut J. Topical microbicides for disease prevention: status and challenges. Clin Infect Dis 2003; 36: 1290-1294.
  • 18. Johnston R. Microbicides 2002: an update. AIDS Patient Care STDS 2002; 16: 419-430.
  • 19. Bentley ME, Morrow KM, Fullem A, et al. Acceptability of a novel vaginal microbicide during a safety trial among low-risk women. Fam Plann Perspect 2000; 32: 184-188.
  • 20. Morrow K, Rosen R, Richter L, et al. The acceptability of an investigational vaginal microbicide, PRO 2000 Gel, among women in a phase I clinical trial. J Womens Health (Larchmt) 2003; 12: 655-666.
  • 21. Ganguli SK, Rekha PP, Gupte N, Charan UA. AIDS awareness among undergraduate students, Maharashtra. Indian J Public Health 2002; 46: 8- 12.
  • 22. Singh MB, Chaudhary RC, Haldiya KR. Knowledge and attitudes of pregnant women regarding AIDS in a semi arid area of Rajasthan. J Commun Dis 1997; 29: 139-144.
  • 23. Singh S, Fukuda H, Ingle GK, Tatara K. Knowledge, attitude, the perceived risks of infection and sources of information.
  • 24. about HIV/AIDS among pregnant women in an urban population of Delhi. J Commun Dis 2002; 34: 23-34.
  • 25. Kotwal A, Priya R, Thakur R, et al. Injection practices in a metropolis of North India: perceptions, determinants and issues of safety. Indian J Med Sci 2004; 58: 334-344.
  • 26. Gisselquist DP. Estimating HIV-1 transmission efficiency through unsafe medical injections. Int J STD AIDS 2002; 13: 152-159.
  • 27. Dhingra-Kumar N, Sharma AK, Madan N. Analysis of quality assurance programmes for HIV screening in blood transfusion centres in Delhi. Bull World Health Organ 1997; 75: 223-228.
  • 28. Chandiramani R. A view from the field: phone help line in India helps indentify HIV risk behaviors. SIECUS Rep 1998; 26: 4-6.
  • 29. Roth J, Krishnan SP, Bunch E. Barriers to condom use: results from a study in Mumbai (Bombay), India. AIDS Educ Prev 2001; 13: 65-77.
  • 30. Agarwal N, Deka D, Takkar D. Contraceptive status and sexual behavior in women over 35 years of age in India. Adv Contracept 1999; 15: 235-244.
  • 31. Baveja R, Buckshee K, Das K, et al. Evaluating contraceptive choice through the method-mix approach. An Indian Council of Medical Research (ICMR) task force study. Contraception 2000; 61: 113-119.
There are 31 citations in total.

Details

Primary Language English
Journal Section Articles
Authors

Suniti Solomon This is me

Kathleen Morrow This is me

Ak Srikrishnan This is me

Jessica Buck This is me

Sreekanth Chaguturu This is me

Rochelle Rosen This is me

Rochelle D'souza Yepthomi This is me

Kenneth Mayer This is me

Publication Date January 21, 2013
Published in Issue Year 2011 Volume: 16 Issue: 2

Cite

APA Solomon, S., Morrow, K., Srikrishnan, A., Buck, J., et al. (2013). HIV risk behavior and acceptability of microbicides in chennai, India. EASTERN JOURNAL OF MEDICINE, 16(2), 160-167.
AMA Solomon S, Morrow K, Srikrishnan A, Buck J, Chaguturu S, Rosen R, Yepthomi RD, Mayer K. HIV risk behavior and acceptability of microbicides in chennai, India. EASTERN JOURNAL OF MEDICINE. March 2013;16(2):160-167.
Chicago Solomon, Suniti, Kathleen Morrow, Ak Srikrishnan, Jessica Buck, Sreekanth Chaguturu, Rochelle Rosen, Rochelle D’souza Yepthomi, and Kenneth Mayer. “HIV Risk Behavior and Acceptability of Microbicides in Chennai, India”. EASTERN JOURNAL OF MEDICINE 16, no. 2 (March 2013): 160-67.
EndNote Solomon S, Morrow K, Srikrishnan A, Buck J, Chaguturu S, Rosen R, Yepthomi RD, Mayer K (March 1, 2013) HIV risk behavior and acceptability of microbicides in chennai, India. EASTERN JOURNAL OF MEDICINE 16 2 160–167.
IEEE S. Solomon, K. Morrow, A. Srikrishnan, J. Buck, S. Chaguturu, R. Rosen, R. D. Yepthomi, and K. Mayer, “HIV risk behavior and acceptability of microbicides in chennai, India”, EASTERN JOURNAL OF MEDICINE, vol. 16, no. 2, pp. 160–167, 2013.
ISNAD Solomon, Suniti et al. “HIV Risk Behavior and Acceptability of Microbicides in Chennai, India”. EASTERN JOURNAL OF MEDICINE 16/2 (March 2013), 160-167.
JAMA Solomon S, Morrow K, Srikrishnan A, Buck J, Chaguturu S, Rosen R, Yepthomi RD, Mayer K. HIV risk behavior and acceptability of microbicides in chennai, India. EASTERN JOURNAL OF MEDICINE. 2013;16:160–167.
MLA Solomon, Suniti et al. “HIV Risk Behavior and Acceptability of Microbicides in Chennai, India”. EASTERN JOURNAL OF MEDICINE, vol. 16, no. 2, 2013, pp. 160-7.
Vancouver Solomon S, Morrow K, Srikrishnan A, Buck J, Chaguturu S, Rosen R, Yepthomi RD, Mayer K. HIV risk behavior and acceptability of microbicides in chennai, India. EASTERN JOURNAL OF MEDICINE. 2013;16(2):160-7.