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Year 2012, Volume: 17 Issue: 3, 149 - 152, 14.03.2014

Abstract

References

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  • Sivasubramanian S, Moorthy S, Sreekumar K, Kannan RR. Diffusion-weighted magnetic resonance imaging in acute reversible toxic leukoencephalopathy: A report of two cases. Indian J Radiol Imaging 2010; 20: 192-194.
  • Gallucci M, Limbucci N, Paonessa A, Caranci F. Reversible focal splenial lesions. Neuroradiology 2007; 49: 541-544.
  • Moritani T, Smoker WR, Sato Y, Numaguchi Y, Westesson PL. Diffusion-weighted imaging of acute excitotoxic brain injury. AJNR Am J Neuroradiol 2005; 26: 216-228.
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Acute leucoencephalopathy with restriction of diffusion-a case report

Year 2012, Volume: 17 Issue: 3, 149 - 152, 14.03.2014

Abstract

Abstract. Acute white matter insult in a non traumatic, non ischemic background has been recently identified in certain clinical situations. Named toxic leukoencephalopathy, it may be caused by exposure to a wide variety of agents, including cranial irradiation, therapeutic agents, drugs of abuse, and environmental toxins. Extensive central white matter restriction of diffusion in the absence of significant T2 or Fluid-attenuated inversion recovery (FLAIR) abnormality is the imaging hallmark on Magnetic Resonance Imaging (MRI). Reversibility of the symptoms after the withdrawal of toxin has been shown in a few reports. We present one such case with reversal of changes on MRI and clinical improvement.

Key words: ADEM, intramyelinic edema, PRES, toxic leukoencephalopathy

References

  • Filley CM, Kleinschmidt-DeMasters BK. Toxic leukoencephalopathy. N Engl J Med 2001; 345: 425- 432.
  • McKinney AM, Kieffer SA, Paylor RT, et al. Acute toxic leukoencephalopathy: Potential for reversibility clinically and on MRI with diffusion-weighted and FLAIR imaging. AJR Am J Roentgenol 2009; 193: 192-206.
  • Schaefer PW, Grant PE, Gonzalez RG. Diffusion- weighted MR imaging of the brain. Radiology 2000; 217:331-345.
  • Nomura Y, Sakuma H, Takeda K, et al. Diffusional anisotropy of the human brain assessed with diffusion-weighted MR: relation with normal brain development and aging. AJNR Am J Neuroradiol 1994; 15: 231-238.
  • Wimberger DM, Roberts TP, Barkovich AJ, et al. Identification of “premyelination” by diffusion- weighted MRI. J Comput Assist Tomogr 1995; 19: 28- 33.
  • McKinney AM, Short J, Truwit CL, et al. Posterior reversible encephalopathy syndrome: Incidence of atypical regions of involvement and imaging findings. AJR Am J Roentgenol 2007; 189: 904-912.
  • Sivasubramanian S, Moorthy S, Sreekumar K, Kannan RR. Diffusion-weighted magnetic resonance imaging in acute reversible toxic leukoencephalopathy: A report of two cases. Indian J Radiol Imaging 2010; 20: 192-194.
  • Gallucci M, Limbucci N, Paonessa A, Caranci F. Reversible focal splenial lesions. Neuroradiology 2007; 49: 541-544.
  • Moritani T, Smoker WR, Sato Y, Numaguchi Y, Westesson PL. Diffusion-weighted imaging of acute excitotoxic brain injury. AJNR Am J Neuroradiol 2005; 26: 216-228.
  • Wani AA, Phadke R, Behari S, et al. Role of
  • diffusion-weighted MRG in predicting outcome in subarachnoid hemorrhage due to anterior communicating artery aneurysms. Turk Neurosurg 2008; 18: 10-16.
There are 11 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Singh Vivek This is me

Tomar Vaishali This is me

Kumar Alok This is me

Phadke Rajendra V. This is me

Publication Date March 14, 2014
Published in Issue Year 2012 Volume: 17 Issue: 3

Cite

APA Vivek, S., Vaishali, T., Alok, K., Rajendra V., P. (2014). Acute leucoencephalopathy with restriction of diffusion-a case report. EASTERN JOURNAL OF MEDICINE, 17(3), 149-152.
AMA Vivek S, Vaishali T, Alok K, Rajendra V. P. Acute leucoencephalopathy with restriction of diffusion-a case report. EASTERN JOURNAL OF MEDICINE. October 2014;17(3):149-152.
Chicago Vivek, Singh, Tomar Vaishali, Kumar Alok, and Phadke Rajendra V. “Acute Leucoencephalopathy With Restriction of Diffusion-a Case Report”. EASTERN JOURNAL OF MEDICINE 17, no. 3 (October 2014): 149-52.
EndNote Vivek S, Vaishali T, Alok K, Rajendra V. P (October 1, 2014) Acute leucoencephalopathy with restriction of diffusion-a case report. EASTERN JOURNAL OF MEDICINE 17 3 149–152.
IEEE S. Vivek, T. Vaishali, K. Alok, and P. Rajendra V., “Acute leucoencephalopathy with restriction of diffusion-a case report”, EASTERN JOURNAL OF MEDICINE, vol. 17, no. 3, pp. 149–152, 2014.
ISNAD Vivek, Singh et al. “Acute Leucoencephalopathy With Restriction of Diffusion-a Case Report”. EASTERN JOURNAL OF MEDICINE 17/3 (October 2014), 149-152.
JAMA Vivek S, Vaishali T, Alok K, Rajendra V. P. Acute leucoencephalopathy with restriction of diffusion-a case report. EASTERN JOURNAL OF MEDICINE. 2014;17:149–152.
MLA Vivek, Singh et al. “Acute Leucoencephalopathy With Restriction of Diffusion-a Case Report”. EASTERN JOURNAL OF MEDICINE, vol. 17, no. 3, 2014, pp. 149-52.
Vancouver Vivek S, Vaishali T, Alok K, Rajendra V. P. Acute leucoencephalopathy with restriction of diffusion-a case report. EASTERN JOURNAL OF MEDICINE. 2014;17(3):149-52.