Iodine status in vulnerable groups of Linxia Hui Autonomous Prefecture, China

Year 2013, Volume: 18 Issue: 2, 68 - 71, 03.07.2013

Pengfei Ge Zhongliang Zhang Yanling Wang Yongqin Cao Jinxiao Xi

Abstract

To assess iodine status in vulnerable groups of Linxia Hui Autonomous Prefecture, China. We selected 5 villages in the east, south, west, north and center of 8 counties of Linxia Hui Autonomous Prefecture randomly. In each village, one primary school was identified and 80 students aged 8-10 years were randomly selected. At the same time, 20 pregnant women, 20 lactating women, 20 women of childbearing age and 20 young children (0-3 years) were randomly selected via existing township health center lists. The iodine content of household salt and drinking water and the urine in four population subsets (except school-aged children) was measured. The thyroids were examined in school-aged children. The iodine content in most household drinking water (90.2%) was less than 10μg/L. The percentage of households using adequately iodized salt was 83.2% and percentage of households using non-iodized salt was as high as 15%. The median urinary iodine concentration (UIC) of pregnant and lactating women, and women of child-bearing age was 89, 85 and 90μg/L, respectively, indicating an iodine deficiency. The median UIC of 0-3 year old babies was 107μg/L. The goiter rates of school-aged children were 10.6% by ultrasound and 9.9% by palpation. Low median UIC and high goiter rates were observed most frequently in counties with higher non-iodized salt and higher percentage of minority nationalities. Iodine deficiency has been a significant public health problem in Linxia Hui Autonomous Prefecture and still exists. Iodine supplement is needed to ensure adequate iodine nutrition for at-risk groups.

Keywords

Iodine deficiency, iodized salt, goiter, urine iodine concentration

References

• WHO/ICCIDD/UNICEF. Assessment of the iodine deficiency disorders and monitoring their elimination. 3rd edition. Geneva: WHO; 2007.
• WHO/UNICEF/ICCIDD (1999). Progress towards the elimination of iodine deficiency disorders Geneva: WHO document WHO/NHD/99.4
• WHO/UNICEF/ICCIDD. Global prevalence of iodine deficiency disorders. Micronutrient deficiency information system working paper No.1. Geneva: WHO, 1991.
• Chen ZP. IDD hazard control progress and challenge. Geriatr Health Care 2010; 16: 6-11.
• Chen ZP. Progress of IDD elimination in China. J Prev Med Inf 2000; 16: 93-94.
• Pino S, Fang SL, Braverman LE. Ammonium persulfate: a new and safe method for measuring urinary iodine by ammonium persulfate oxidation. Exp Clin Endocrinol Diabetes 1998; 106: 22-27.
• China’s Ministry of Health. The recommended method for measuring iodine in drinking water. Ministry of Health, Beijing. 2001, Document No. 161 (in Chinese).
• Liu LJ, Yin J, Zheng ZH. Determination of iodine in urine mild and vigorous digestion methods followed by ceric arsenite reaction. Chinese J Endemiology 1995; 14: 37-39.
• WHO/UNICEF/ICCIDD (1996). Recommended iodine levels in salt and guidelines for monitoring their adequacy and effectiveness. Geneva: WHO.
• WHO/UNICEF/ICCIDD. Reaching optimal iodine nutrition in pregnant and lactating women and young children. IDD NEWSLETTER 2008; 27: 1-3.
• State Bureau of Quality Technical Supervision. The normal value of thyroid volume in children and adolescents. Chinese Criteria Publishing House, Beijing. 1996, GB16398-1996 (in Chinese).
• China’s Ministry of Health and State Bureau of Quality Technical Supervision. The Criteria of Elimination of IDD. Chinese Criteria Publishing House Beijing: 1995, GB16006-1995(in Chinese). Wang Y, Zhang Z, Ge P, Wang Y, Wang S. Iodine deficiency disorders after a decade of universal salt iodization in a severe iodine deficiency region in China. Indian J Med Res 2009; 130: 413-417.
• Gordon RC, Rose MC, Skeaff SA, et al. Iodine supplementation improves cognition in mildly iodinedeficient children. Am J Clin Nutr 2009; 90: 1264 12
• Wang Y, Zhang Z, Ge P, Wang Y, Wang S. Iodine status and thyroid function of pregnant, lactating women and infants (0-1 yr) residing in areas with an effective Universal Salt Iodization program. Asia Pac J Clin Nutr 2009; 18: 34-40.