Investigation of Bipolar Disorder with Resting state functional MR

Year 2019, Volume: 15 Issue: 3, 44 - 56, 30.12.2019

Semra İçer Abdullah Baş

Abstract

Bipolar
bozukluk yıllar geçtikçe görülme sıklığı lineer olarak yükselen ve psikolojik
rahatsızlıklarda en fazla görülen hastalıklardan biridir. Bipolar bozukluk,
enerjide değişimler, ruh halinde değişimler ve ölüm ya da intihar düşüncesi
gibi semptomlarla kendini gösterebilir. Fonksiyonel MR non-invaziv yapısı,
yüksek uzaysal ve zamansal çözünürlüğü sağlaması nedeniyle son yıllarda tercih
edilmektedir. Çalışmamızda 21-50 yaş aralığında 45 (20 Kadın,25 Erkek) bipolar
bozukluk hastası katılımcı , yine 21-50 yaş arasında 45 (20 Kadın, 25 Erkek)
sağlıklı kontrol grubu katılımcısı üzerinde analizler gerçekleştirilmiştir.
Dİnlenim hali fMRG  verilerini
kullandığımız çalışmada “ROI to ROI” analiz metodu kullanılarak verilerin
fonksiyonel bağlantısallığı incelenmiştir. İki grup arasında,  cingulate korteks, orbifrontal korteks ,
posterior parietal korteks, priform korteks, entorhinal korteks ve
ventral-medial prefrontal korteks bölgelerinde anlamlı korelasyon farklılıkları
bulunmuştur.(pFDR<0.05). Bu çalışma,
Erciyes Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü (BAP:
FYL-2018-8277) tarafından desteklemiştir.

Keywords

Resting functional MR

Project Number

BAP: FYL-2018-8277

References

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