Kolorektal Kanserde Endoskopik Özelliklerler Tümör Patolojisini ve Tümör Evresini Predikte Edebilir mi?

Year 2018, , 84 - 90, 28.12.2018

Muhammet Yener Akpınar , Metin Uzman , Zeynep Göktaş Gülçin Güler Şimşek Evrim Kahramanoğlu Aksoy , Ferdane Sapmaz , Yaşar Nazlıgül

https://doi.org/10.17940/endoskopi.503018

Abstract

Giriş ve Amaç: Kolorektal kanserli hastalarımızın demografik
özelliklerini ve tanı anındaki endoskopik özelliklerinin kolorektal kanserin
patolojik özellikleri ile olan ilişkisini incelemeyi hedefledik. Gereç ve Yöntem: Hastanemiz Endoskopi Ünitesinde Ocak 2010-Ekim 2017
tarihleri arasında kolonoskopi esnasında kolorektal kanser ön tanısı ile
biyopsi alınan ve patolojileri kolorektal kanser gelen hastalar çalışmaya dahil
edildi. Tümöre bağlı lüminal obstrüksiyon, tümörün makroskopik özellikleri gibi
endoskopik özellikler ve kolorektal kanserin patolojik özellikleri retrospektif
olarak incelendi.  Bulgular: Çalışmamıza 168 hasta dahil edildi. Hastaların en
sık başvuru şikayeti kabızlık olup kolonda kanserin en sık izlendiği yer
sigmoid kolondu. Hematokezya sol kolon yerleşimli kanserlerde diğer
bölgelerdekine göre anlamlı olarak daha sık izlendi (p=0.02). Cinsiyetler
arasında başvuru şekli, kanser lokalizasyonu ve endoskopik obstrüksiyon
farklılık göstermedi. Endoskopik obstrüksiyonu olan hastalarda kolorektal
kanserin kötü diferansiasyonu anlamlı olarak daha fazlaydı (p=0.015). Sonuç: Endoskopun geçemeyeceği şekilde lüminal obstrüksiyonu
olan hastaların yakından izlenmeleri, ameliyatlarının geciktirilmeden yapılması
ve ameliyat sonrası daha kısa aralıklarla takibi bu hastaların sağkalımları üzerine
etkili olabilir.

Keywords

Endoskopi, kanser diferansiasyonu, kolorektal kanser

Can the Endoscopic Features of Colorectal Carcinomas Predict Tumor Pathology and Stage?

Abstract

Background and Aims: Our aim was to evaluate the
demographic features of our colorectal cancer patients and assess the
association between endoscopic and pathologic features in those patients. Materials and Methods: In this study, we retrospectively evaluated the medical
records of patients who were diagnosed with colorectal cancer through biopsy taken by colonoscopy in the endoscopy
unit of our hospital between January 2010 and October 2017. We analyzed endoscopic
features of colorectal cancer such as luminal obstruction, macroscopic
appearance, and histological features. Results: We obtained data from 168 patients for this study.
The most common symptom was constipation and the most common cancer location
was the sigmoid colon. Hematochezia was found to be significantly higher in
cancers located in the left colon (p = 0.02).  Symptoms, cancer location, and endoscopic
obstruction were not significantly different between genders. Poor histological
differentiation was significantly higher in the endoscopic obstruction group (p
= 0.015). Conclusion: Immediate surgery and close
follow-up in patients with endoscopic obstruction can impact their survival.

Keywords

Colorectal cancer, cancer differentiation, endoscopy

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