Helicobacter pylori gastriti için tanımlanan etat mamillone görünümünün histopatolojik bulgular ile korelasyonu

Year 2019, , 12 - 15, 15.04.2019

Volkan Gökbulut , Mustafa Kaplan , Adem Aksoy Selçuk Dişibeyaz Bülent Ödemiş Erkin Öztaş , Meral Akdoğan Kayhan Ertuğrul Kayaçetin

https://doi.org/10.17940/endoskopi.569725

Abstract

Giriş
ve Amaç: Etat mamillone endoskopik
olarak gözlenen ve Helicobacter pylori pozitif
olan hastalarda mukozal nodüler tutulum ile karakterize
kolaylıkla tanınabilen karakteristik bir bulgudur. Biz
bu çalışmada etat mamillone görüntüsü nedeniyle endoskopik biyopsi alınan
hastalarda bu görüntünün histopatolojik tanıya göre doğruluğunu araştırdık. Gereç ve Yöntem: Bu çalışma Ocak
2016-Aralık 2017 tarihleri arasında hastanemiz gastroenteroloji kliniğinde
çeşitli sebeplerle endoskopi yapılan hastaların hasta kayıtları incelenerek
retrospektif olarak yapılmıştır. Toplamda 5200 endoskopi kaydı incelenmiş, etat
mamillion veya etat mamillone tabiri geçen 53 hasta çalışmaya dahil edilmiştir.
Bulgular: Araştırma popülasyonu 41
kadın (%77) ve 12 erkek (%23)  erkek
hasta olmak üzere 53 kişiden oluştu. Hastaların ortalama yaşı 29±11.2 (18-56)
yıldı. Hastaların endoskopik biyopsi sonuçlarına bakıldığında 4 (%8) hastada
atrofik gastrit mevcut iken 49 (%92) hastada atrofi yoktu. Hastaların biyopsi
örnekleri incelendiğinde 53 hastanın 45’inde Helicobacter pylori pozitif
saptandığı görüldü (%85). Bu hastaların Sydney sınıflamasına göre 12’sinde 1+ Helicobacter
pylori (%23),
17’sinde 2+ Helicobacter pylori (%32)  ve 16’sında 3+ Helicobacter pylori (%30)  saptanmıştır. Endoskopik etat mamillone
görüntüsü ile biyopsi sonuçları arasında %85 oranında korelasyon olduğu görülmüştür.
Sonuç:
Endoskopik
olarak tanımlanan etat mamillone görünümü Helicobacter pylori gastriti
tanısı için kullanılabilecek non-invaziv ve yüksek doğruluk oranına sahip bir
yöntemdir.

Keywords

Etat mamillion, Sydney sınıflaması, Helicobacter pylori gastriti

Correlation of etat mamillone appearance with histopathological findings for Helicobacter pylori gastritis

Abstract

Background and Aims: Etat mamillone
is an endoscopic appearance characterized by mucosal nodular involvement in
patients with Helicobacter pylori
gastritis. In the present study, we investigated the accuracy of this appearance
on the basis of histopathological diagnosis in patients who underwent
endoscopic biopsy for etat mamillone. Material
and Methods: The present study was performed retrospectively between
January 2016 and December 2017 in the gastroenterology clinic of our hospital.
A total of 5200 endoscopy records were examined, and 53 patients with etat
mamillion or etat mamillone were included in the study. Results: The study population consisted of 53 patients, 41 of whom
were female (77%) and 12 male (23%). The mean age of the patients was 29±11.2
years (range: 18–56 years). Atrophic gastritis was observed in four patients (8%),
while 49 patients (92%) had no atrophy. Upon biopsy, 45 of the 53 patients
(85%) were found to be Helicobacter pylori positive.
According to the Sydney classification, 12 patients had 1+ Helicobacter
pylori (23%),
17 had 2+ Helicobacter pylori (32%),
and 16 had 3+ Helicobacter pylori (30%).
There was 85% correlation between the endoscopic etat mamillone appearance and
biopsy results. Conclusion: Endoscopic etat mamillone appearance is a
non-invasive and highly accurate method for diagnosis of Helicobacter
pylori gastritis.

Keywords

Etat mamillion, Sydney classification, Helicobacter pylori gastritis

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