Dabigatrana bağlı özofagus ülseri

Year 2017, Volume: 25 Issue: 2, 47 - 48, 29.08.2017

Hakan Ümit Ünal Özlem Saygılı Murat Saruç

https://doi.org/10.17940/endoskopi.339868

Abstract

Dabigatran trombin inhibisyonu yaparak antikoagülan etki gösteren bir ön ilaçtır. Rutin labovatuar takibi ve doz titrasyonu gerektirmemesi varfarine göre kullanım avantajı sağlanken, gastrointestinal sistem üzerine daha sık yan etki oluşturması önde gelen dezavantajlarındandır. Bizim vakamız, dabigatran kullanımına bağlı gelişen özofagus ülser hastasıdır.

Keywords

Dabigatran, ilaca bağlı özofageal ülser, antikoagülan etki

Dabigatran-induced esophageal ulcer

Abstract

Dabigatran,
which has an anticoagulant effect by inhibiting the action of thrombin, is a
prodrug. An advantage of this drug over warfarin is that it does not require
routine laboratory monitoring and dose adjustments. However, adverse effects on
the gastrointestinal system are more common in patients using dabigatran than
in patients using warfarin. In the present study, we report a case of
dabigatran-induced esophageal ulcer.

Keywords

Dabigatran, drug-induced esophageal ulcer, anticoagulant effect

References

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