Effect of H. pyloripresence on the severity of Crimean Congo hemorrhagic fever

Year 2014, Volume: 22 Issue: 1, - , 01.04.2014

İlyas Dökmetaş Özlem Yönem Sebila Dökmetaş Levent Özdemir Fatih Kılıçlı Aynur Engin İbrahim Büyükhan

https://doi.org/10.17940/endoskopi.74789

Cited By: 1

Abstract

Background and Aims:Crimean Congo hemorrhagic fever can cause a fatal hemorrhagic syndrome. We aimed to investigate whether the presence of Helicobacter pylori increases the bleeding or severity of Crimean Congo hemorrhagic fever. Materials and Methods:Forty-two patients with Crimean Congo hemorrhagic fever who had dyspepsia and were hospitalized between April 2009 and July 2009 were included in the study. The patients were divided into two groups according to their fecal Helicobacter pylori antigen positivity. Clinical and laboratory severity criteria for Crimean Congo hemorrhagic fever were investigated in both groups. Results:We could not find any difference between the two groups with regard to severity as defined by clinical and laboratory criteria. Conclusion: This is the first study in the literature investigating the role of Helicobacter pylori in the severity of Crimean Congo hemorrhagic fever from a country in which both Crimean Congo hemorrhagic fever and Helicobacter pylori are endemic. Further studies including a larger number of Crimean Congo hemorrhagic fever patients are necessary to recommend Helicobacter pylori screening and eradication in Crimean Congo hemorrhagic fever.

Keywords

Crimean Congo hemorrhagic fever, Helicobacter pylori, severity

Kırım Kongo kanamalı ateşine H. pylorivarlığının etkisi

Abstract

Giriş ve Amaç:Kırım Kongo kanamalı ateşi ölümcül hemorajik bir sendroma neden olabilir. Bu çalışmada Helicobacter pylori varlığının Kırım Kongo kanamalı ateşi hastalığının şiddeti ya da kanama üzerine etkisinin olup olmadığını araştırdık. Gereç ve Yöntem:Kırım Kongo kanamalı ateşi nedeniyle Nisan 2009-Temmuz 2009 arası hospitalize edilen kırk iki dispeptik hasta çalışmaya dahil edildi. Hastalar fekal Helicobacter pylori antijeni pozitifliği durumuna göre iki gruba ayrıldı. Her iki grupta Kırım Kongo kanamalı ate-şi'nin klinik ve labaratuvar olarak şiddet kriterleri değerlendirildi. Bulgular: Klinik ve laboratuvar kriterleri açısından iki grup arasında Kırım Kongo kanamalı ateşi hastalık şiddeti açısından farklılık saptanmadı. Sonuç: Bu çalış-ma Helicobacter pylori'nin Kırım Kongo kanamalı ateşi'nin şiddeti üzerine etkisini araştıran ilk çalışma olması ve hem Helicobacter pylori hem de Kırım Kongo kanamalı ateşi'nin endemik olduğu bir bölgeden yapılması nedeniyle önemlidir. Ancak Kırım Kongo kanamalı ateşi hastalarında rutin Helicobacter pylori taranması ve eradikasyonunun önerilebilmesi için daha geniş vaka sayılı çalışmalara ihtiyaç vardır.

Keywords

Kırım Kongo kanamalı ateşi, Helicobacter pylori, şiddet

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