Abstract
Background/aims: The relationship between Helicobacter pylori and beta-2 microglobulin in patients with portal gastropathy has not been clearly defined yet. In this study, we aimed to compare the levels of serum and tissue beta-2 microglobulin in patients with and without Helicobacter pylori infection and to examine the relationship between levels of serum and tissue beta-2 microglobulin in patients with portal gastropathy. Methods: Twenty-five patients with portal gastropathy and 22 healthy persons were enrolled in this study. Gastric biopsies were histologically analyzed and tissue and serum beta-2 microglobulin levels were measured. Results: Helicobacter pylori infection was detected in 15 of 25 portal gastropathy patients. Subendothelial beta-2 microglobulin was detected in 8 of 15 (53.3%) portal hypertensive gastropathy patients with Helicobacter pylori. Subendothelial beta-2 microglobulin was detected in 3 of 10 (30%) portal hypertensive gastropathy patients without Helicobacter pylori. The difference between groups was statistically significant (p
References
- Conz PA, Dante S, Bernardini D, et al. Beta2 microglobulin and Helico- bacter pylori infection in uremic dialysed patients. J Gastroenterol Hepa- tol 1992; 7: 191-3.
- Iwao T, Toyanaga A, Sumino M, et al. Portal hypertensive gastropathy in patients with cirrhosis. Gastroenterology 1992; 102: 2060-5.
- Foster PN, Wyatt JI, Bullimore DW, et al. Gastric mucosa in patients with portal hypertension. Prevalence of capillary dilation and Campylo- bacter pylori. J Clin Pathol 1989; 42: 919-21.
- D’Amico G, Montalbano L, Traina M, et al. Natural history of congestive gastropathy in cirrhosis. Gastroenterology 1990; 99: 1558-64.
- McCormick PA, Sankey A, Cardin F, et al. Congestive gastropathy and H. pylori: an endoscopic and morphometric study. Gut 1991; 32: 351- 4.
- Özdemir S, Şenturk H, Sezgiç N et al. The frequency of Helicobacter pylori infection in cirrhotic gastropathy. Gastroenteroloji Dergisi 1992; 1: 109-12.
Abstract
Amaç: Portal gastropatili hastalarda Helikobakter pilori ve beta-2 mikroglobulin ilişkisi net olarak tanımlanamamıştır. Bu çalışmada, Helikobakter pilori infeksiyonu olan ve olmayan hastaların serum ve doku beta-2 mikroglobulin düzeyleri ve bu düzeylerin portal gastropati ile ilişkisi incelenmiştir. Gereç ve Yöntem: Portal gastropatili 25 hasta ve 22 sağlıklı birey çalışmaya dahil edilmiştir. Mide biyopsileri incelenmiş, serum ve doku beta-2 mikroglobulin düzeyleri bakılmıştır. Bulgular: Yirmibeş portal hipertansif gastropatili olgunun 15'inde Helikobakter pilori infeksiyonu bulunmuştur. Bu 15 hastanı n 8'inde (%53.3) subendotelial beta-2 mikroglobulin artışı görülmüştür. Helikobakter pilori olmayan 10 hastanın 3'ünde (%30) subendotelial beta-2 mikroglobulin bulunmuştur. Fark istatistiksel olarak anlamlıdır (p
References
- Conz PA, Dante S, Bernardini D, et al. Beta2 microglobulin and Helico- bacter pylori infection in uremic dialysed patients. J Gastroenterol Hepa- tol 1992; 7: 191-3.
- Iwao T, Toyanaga A, Sumino M, et al. Portal hypertensive gastropathy in patients with cirrhosis. Gastroenterology 1992; 102: 2060-5.
- Foster PN, Wyatt JI, Bullimore DW, et al. Gastric mucosa in patients with portal hypertension. Prevalence of capillary dilation and Campylo- bacter pylori. J Clin Pathol 1989; 42: 919-21.
- D’Amico G, Montalbano L, Traina M, et al. Natural history of congestive gastropathy in cirrhosis. Gastroenterology 1990; 99: 1558-64.
- McCormick PA, Sankey A, Cardin F, et al. Congestive gastropathy and H. pylori: an endoscopic and morphometric study. Gut 1991; 32: 351- 4.
- Özdemir S, Şenturk H, Sezgiç N et al. The frequency of Helicobacter pylori infection in cirrhotic gastropathy. Gastroenteroloji Dergisi 1992; 1: 109-12.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | December 1, 2011 |
| Published in Issue | Year 2011 Volume: 19 Issue: 3 |