Review

Efervesan tabletler: ilaç kullanımı için güvenli ve pratik bir uygulama sistemi

Volume: 6 Number: 1 April 30, 2016
  • Kağan İpci
  • Tuğba Öktemer
  • Leman Birdane
  • Niyazi Altıntoprak
  • Nuray Bayar Muluk
  • Desiderio Passali
  • Andrey Lopatin
  • Luisa Bellussi
  • Ranko Mladina
  • Ruby Pawankar
  • Cemal Cingi
EN

Efervesan tabletler: ilaç kullanımı için güvenli ve pratik bir uygulama sistemi

Abstract

Effervescence is defined as the evolution of gas bubbles from a liquid as a result of a chemical reaction. For medicinal use, effervescent tablets have specific characteristics that allow rapid adsorption of the intended drug. In this manner, a medication can be absorbed easily and effectively if it dissolves easily in water and is present at a sufficient dose. Common acids utilized for effervescent reactions are citric, malic, tartaric, adipic and fumaric acids. Citric acid is most commonly used for this application, which also adds a citrus-like taste to the products. Tartaric, adipic and fumaric acids are usually used in small amounts, due to their low water solubility. Effervescent tablets are used to simplify the handling of doses, provide optimal compatibility, promote superior and rapid absorption, increase a patient’s liquid intake and circumvent the difficulty of swallowing large pills. This review defines effervescent tablets in terms of the technology and describes the advantages and disadvantages.

Keywords

References

  1. 1. Rajlakshmi G, Vamsi C, Balchandar R, Damodharan N. Formulation and evaluation of effervescent tablets of diclofenac potassium. International Journal of Pharmaceutical and Biomedical Research 2011;2;237–43.
  2. 2. Mohrle R. Effervescent tablets. In: Liberman HA, Lachman L. Schwartz JB, editors. pharmaceutical dosage form–tablets. Vol. I. First Indian reprint. New York, NY: Marcel Dekker Inc.; 2005. p. 285–92.
  3. 3. Stahl H. Effervescent dosage manufacturing. Pharmaceutical Technology Europe 2003;15:25–8.
  4. 4. Swarbrick J, Boylon JC. Encyclopedia of pharmaceutical technology. Vol. 1. New York, NY: Marcel Dekker Inc.; 2002. p. 1037–49.
  5. 5. Tekade BW, Jadhao UT, Thakre VM, Bhortake LR. Formulation and evaluation of diclofenac sodium effervescent tablet. Innovations in Pharmaceuticals and Pharmacotherapy 2014;2:350–8.
  6. 6. Prabhakar CH, Krishna KB. A review on effervescent tablet. International Journal of Pharmacy and Technology 2011;3:704–12. 7. Sweetman SC. Martindle: the complete drug reference. 35th ed. London: Pharmaceutical Press; 2007.
  7. 8. Aslani A, Fattahi F. Formulation, characterization and physicochemical evaluation of potassium citrate effervescent tablets. Adv Pharm Bull 2013;3:217–25.
  8. 9. Pham JH. Understanding effervescent tableting technology [cited 2015 Nov 29]. Available from:.http://www.naturalproductsinsider. com/articles/2008/05/understanding-effervescenttableting- technology.aspx

Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Review

Authors

Kağan İpci This is me

Tuğba Öktemer This is me

Leman Birdane This is me

Niyazi Altıntoprak This is me

Nuray Bayar Muluk This is me

Desiderio Passali This is me

Andrey Lopatin This is me

Luisa Bellussi This is me

Ranko Mladina This is me

Ruby Pawankar This is me

Cemal Cingi This is me

Publication Date

April 30, 2016

Submission Date

July 21, 2017

Acceptance Date

-

Published in Issue

Year 1970 Volume: 6 Number: 1

APA
İpci, K., Öktemer, T., Birdane, L., Altıntoprak, N., Bayar Muluk, N., Passali, D., Lopatin, A., Bellussi, L., Mladina, R., Pawankar, R., & Cingi, C. (2016). Efervesan tabletler: ilaç kullanımı için güvenli ve pratik bir uygulama sistemi. ENT Updates, 6(1), 46-50. https://izlik.org/JA99CU48BH
AMA
1.İpci K, Öktemer T, Birdane L, et al. Efervesan tabletler: ilaç kullanımı için güvenli ve pratik bir uygulama sistemi. ENT Updates. 2016;6(1):46-50. https://izlik.org/JA99CU48BH
Chicago
İpci, Kağan, Tuğba Öktemer, Leman Birdane, et al. 2016. “Efervesan Tabletler: Ilaç Kullanımı Için Güvenli Ve Pratik Bir Uygulama Sistemi”. ENT Updates 6 (1): 46-50. https://izlik.org/JA99CU48BH.
EndNote
İpci K, Öktemer T, Birdane L, Altıntoprak N, Bayar Muluk N, Passali D, Lopatin A, Bellussi L, Mladina R, Pawankar R, Cingi C (April 1, 2016) Efervesan tabletler: ilaç kullanımı için güvenli ve pratik bir uygulama sistemi. ENT Updates 6 1 46–50.
IEEE
[1]K. İpci et al., “Efervesan tabletler: ilaç kullanımı için güvenli ve pratik bir uygulama sistemi”, ENT Updates, vol. 6, no. 1, pp. 46–50, Apr. 2016, [Online]. Available: https://izlik.org/JA99CU48BH
ISNAD
İpci, Kağan - Öktemer, Tuğba - Birdane, Leman - Altıntoprak, Niyazi - Bayar Muluk, Nuray - Passali, Desiderio - Lopatin, Andrey et al. “Efervesan Tabletler: Ilaç Kullanımı Için Güvenli Ve Pratik Bir Uygulama Sistemi”. ENT Updates 6/1 (April 1, 2016): 46-50. https://izlik.org/JA99CU48BH.
JAMA
1.İpci K, Öktemer T, Birdane L, Altıntoprak N, Bayar Muluk N, Passali D, Lopatin A, Bellussi L, Mladina R, Pawankar R, Cingi C. Efervesan tabletler: ilaç kullanımı için güvenli ve pratik bir uygulama sistemi. ENT Updates. 2016;6:46–50.
MLA
İpci, Kağan, et al. “Efervesan Tabletler: Ilaç Kullanımı Için Güvenli Ve Pratik Bir Uygulama Sistemi”. ENT Updates, vol. 6, no. 1, Apr. 2016, pp. 46-50, https://izlik.org/JA99CU48BH.
Vancouver
1.Kağan İpci, Tuğba Öktemer, Leman Birdane, Niyazi Altıntoprak, Nuray Bayar Muluk, Desiderio Passali, Andrey Lopatin, Luisa Bellussi, Ranko Mladina, Ruby Pawankar, Cemal Cingi. Efervesan tabletler: ilaç kullanımı için güvenli ve pratik bir uygulama sistemi. ENT Updates [Internet]. 2016 Apr. 1;6(1):46-50. Available from: https://izlik.org/JA99CU48BH