Koyun Türünde RNA-Dizileme ve Gen İfadesi Üzerine Bibliyometrik Analiz ve Bilimsel Haritalama

Abstract

Bu çalışmada, Web of Science (WoS) veri tabanında 2011-2023 yılları arasında koyunlarda 'RNA dizileme ve gen ifadesi' konulu araştırma makalelerinin gelişiminin bilimsel haritalama yöntemi ile belirlenmesi amaçlanmıştır. Bu kapsamda, ilgili anahtar kelimeler kullanılarak yapılan ilk taramada 205 makale incelenmiş ve 124 makale analize uy-gun bulunmuştur. Bu makaleler Bibliometrix R paketinin Shiny web uygulaması ve VOSviewer ile analiz edilmiştir. Sonuçlar, ilgili alanda en çok yayın yapılan ülkenin Çin, en çok çalışma yapılan ilgili kurumun "The University of Edin-burgh", en çok yayın yapılan derginin ise "PLoS One" olduğunu ortaya koymuştur. Anahtar kelime analizine göre trend konuları granüloza hücreleri üzerine yapılan çalışmalardan başlayarak bağışıklık tepkisi, büyüme, yolak ve et kalitesi gibi araştırma alanlarına doğru ilerlemiştir. Özet analizinde 'transkriptom' kelimesi ile meme bezi, kas, fertilite, PBMC, laktasyon, yağ depolama gibi kelimeler bir arada bulunurken, parazitik ajanlar, ilaç direnci, miRNA çalışmalarını oluşturan kelimeler farklı gruplarda kümelenmiştir. İncelenen dönemde elde edilen makalelerin azlığı çalışma alanının açıklığını ortaya koymaktadır. Bu konuda çalışma planlayacak araştırmacıların farklı koyun ırklarına ait varyantların belirlenmesi, koyunlarda kullanılan antiparaziter ilaçlara direnç, et verimi, hastalıklara direnç, üreme doku ve organları gibi konularda çalışmalar planlayabilecekleri gibi tüm bu çalışmaları iklim değişikliği ve küresel ısınma faktörüne dayalı çalışma konuları olarak tasarlamaları önerilebilir.

Keywords

• Bibliyometrik analiz
• gen ifadesi
• koyun
• RNA-dizileme

Bibliometric Analysis and Science Mapping on RNA-seq and Gene Expression in Sheep

Abstract

This study aimed to determine the development of research articles on ‘RNA-sequencing and gene expres-sion’ in sheep between 2011-2023 in the Web of Science (WoS) database by scientific mapping method. In this regard, 205 articles were examined in the first search using the relevant keywords, and 124 articles suitable for analysis. They were analysed with the Shiny web application of the Bibliometrix R package, and VOSviewer. The results determined that the country with the most publications in the relevant field was China, the related institution with the most studies was “The University of Edinburgh”, and the journal with the most publications was “PLoS One”. According to the key-word analysis, the trend topics started from studies on granulosa cells and showed into research areas such as im-mune response, growth, pathway and meat quality. In the abstract analysis, the word ‘transcriptome’ and words such as mammary gland, muscle, fertility, Peripheral Blood Mononuclear Cells (PBMCs), lactation, fat storage were found together, while the words forming the parasitic agents, drug resistance, miRNA studies were clustered in different groups. The scarcity of the articles obtained in the analysed period reveals the openness of the study area. It can be suggested that the researchers who will plan to work on this subject can plan studies on the identification of variants belonging to different sheep breeds, resistance to antiparasitic drugs used in sheep, meat yield, disease resistance, reproductive tissues and organs, as well as designing all these studies as study subjects based on climate change and global warming factor.

Keywords

• Bibliometric analysis
• gene expression
• RNA-sequencing
• sheep

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