Kedi ve Köpeklerde Abdominal Cerrahi ve Jinekolojik Operasyonlar Sonrası İntra-Abdominal Adezyon Oluşumu ve Medikal Olarak Önlenmesi

Abstract

İntra-abdominal adezyon, başta jinekolojik operasyonlar olmak üzere pek çok abdominal cerrahi girişim sonrası ortaya çıkan; ağrı, intestinal veya üretral tıkanma gibi klinik semptomlarla kendini gösteren önemli bir komplikasyondur. Abdominal boşlukta fibrin oluşumu adezyon patofizyolojisinin temelini oluşturmaktadır. İntra-abdominal adezyonların önlenmesi ile ilgili pek çok pre-klinik ve klinik çalışmalar yapılmıştır. Bu çalışmalarda hedef, adezyon mekanizmasını iyi anlamak, bu mekanizmanın bir noktasından girerek zincirin kırılmasını sağlamak ve böylece adezyon oluşumunu engellemektir. Bu amaçla, farklı etki mekanizmasına sahip pek çok madde kullanılmaktadır. Bu derlemede, adezyonun oluşum mekanizmasının ayrıntılı olarak ortaya konması, intra-abdominal adezyon oluşumunu önlemek için güncel tedavi yöntemlerinin kedi ve köpeklerde abdominal cerrahi ve jinekolojik operasyonlar sonrası uygulanabilirliğinin araştırmacı ve klinisyenlerle paylaşılması amaçlanmıştır.

Keywords

• İntra-abdominal adezyon,kedi,köpek,operasyon

Intra-Abdominal Adhesion Physiology and Prevention with medical treatment after Gynecologic Operations in Cats and Dogs

Abstract

Intra-abdominal adhesions may occur after abdominal surgical approach, especially gynecological operations, represent important clinical symptoms such as pain and intestinal or urethral obstruction. The formation of fibrin in the abdominal cavity is essential for adhesion pathophysiology. Several clinical studies were done about prevention of intra-abdominal adhesions. Aim of these studies was to understand adhesion mechanism and to prevent adhesion formations. For this purpose, many agents are used with different mechanisms. In this review, it aimed to reveal in detail the mechanism of adhesion formation, to share prevention of intra-abdominal adhesions with current treatment methods especially after abdominal surgery and gynecological operations in cats and dogs with colleagues and clinicians.

Keywords

• Cat,dog,intra-abdominal adhesion,operation

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