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Embryonic Stem Cells

Year 2012, Volume: 9 Issue: 1, 65 - 71, 01.03.2012

T. Karaşahin

Abstract

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Keywords

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References

  • Amit M, Margulets V, Segev H, Shariki K, Laevsky I, Coleman R, Elder J. Human feeder layers for human embryonic stem cells. Biol Reprod, 2004; 70:837-45.
  • Baran ÖP, Nergiz Y, Bahçeci S. Göbek kordo- nu kan ve stromal kökenli hücrelerin sinir hüc- relerine farklılaşması. Dicle Tıp Dergisi, 2007; 34:233-8.
  • Beksaç M, Çörtoğlu S, Kansu E, Öztürk M. Kök hücre araştırmalarında güncel kavramlar. Türkiye Bilimler Akademisi Raporları, 2004; sayı:7.
  • Bjorklund LM, Sanchez-Pernaute R, Chung S, Andersson T, Chen IY, McNaught KS, Brownell AL, Jenkins BG, Wahlestedt C, Kim KS, Icasson O. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a parkinson rat model. Proc Nath Acad Sci, 2002; 99:2344-9.
  • Chambers I, Smith A. Self- renewal of teratocarcinoma and embryonic stem cells. Oncogene, 2004; 23(43):7150-60.
  • Chung Y, Klimanskaya I, Becker S, Li T, Maserati M, Lu SJ, Zdravkovic T, Ilic D, Genbacev O, Fisher S, Krtolica A, Lanza R. Human embryonic stem cell lines generated without embryo destruction. Cell Stem Cell Doi, 2008; 10.1016/j.stem. 2007.12.013.
  • Cibelli JB, Stice SL, Golueke PJ, Kane JJ, Jerry J, Blackwell C, Ponce de Lond FA, Robl JM. Cloned transgenic calves produced from nonquiescent fetal fibroblasts. Science 1998; 280(5367):1256-1258 (Abstract).
  • Doss MX, Koehler CI, Gissel C, Hescheler J, Sachinidis A. Embryonic stem cells: a promising tool for cell replacement therapy, J Cell Mol Med, 2004; 8, 4:465-73.
  • Evans MJ, Kaufman MH. Establishment in culture of pluripotent tail cells from mouse embryos. Nature, 1981; 292:154-6.
  • Graves KH, Moreadith RW. Derivation and characterization of putative pluripotential embryonic stem cells from preimplantation embryos. Mol Reprod Dev, 1993; 36:424-33.
  • Güneş AM. Kök hücre plastisitesi ve tıptaki kullanım alanları. Güncel Pediatri, 2005; 36- 42.
  • Hollands P. Differantiation of embryonic haematopoietic stem cells from mouse blastocyst growing in vitro. Development, 1987; 99: 69-76.
  • Hyslop LA, Stojkovic M, Armstrong L, Walter T, Stojkovic P, Przyborski S, Herbert M, Murdoch A, Strachan T, Lako M. Downregulation of NANOG induces differentiation of human embryonic stem cell extraembryonic lineages. Stem Cells, 2005; 23: 1035-43.
  • Kahraman S, Candan ZN. İnsan embriyonik kök hücreleri. Türkiye Klinikleri J Surg Med Sci, 2006; 43:21-5.
  • Kansu E. Kök hücre biyolojisi ve plastisitesin- de güncel kavramlar. ANKEM Dergisi, 2006; 20(ek-2):1-8.
  • Kawasaki H, Mizuseki K, Nishikawa S, Kaneko S, Kuwana Y, Nakanishi S, Nishikawa SI, Sasai Y. Induction of midbrain dopaminergic neurons from ES cells by stromal cell derived inducing activity. Neuron, 2000; 1(28):31-40.
  • Kutlay N, Gül RTB, Güven T, Sert G, Gün M, Erzik C. Kök hücre araştırmalarının etik ve hukuk boyutuna ilişkin rapor. Türkiye Biyoetik Derneği Kök Hücre Araştırmaları ve Uygula- maları Kurulu, 2009.
  • Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarsinoma. Stem Cells, 1981; 78(12):7634-8.
  • Matsui Y, Zsebo K, Hogan BLM. Derivation of pluripotential embryonic stem cells frommurine primordial germ cells in culture. Cell, 1992; 70(5): 841-847.
  • Mitalipova M, Beyhan Z, First NL. Pluripotency of bovine embryonic cell line derived from precompacting embryos. Cloning, 2001; 3 (2):59-67.
  • Moore KA, Ema H, Lemischka IR. In vitro maintenance of highly purified, transplantable hematopoietic. Stem Cells Blood, 1997; 89 (12) :4337-47.
  • Peura TT, Bosman A, Stojanov T. Derivation of human embryonic stem cell lines. Theriogenology, 2007; 67:32-42.
  • Richards M, Tan S, Fong CY, Biswas A, Chan WK, Bongso A. Comperative evaulation of various human feeders for prolonged undifferentiated growth of human embryonic stem cells. Stem Cells, 2003; 21:546-56.
  • Robson P, Stein P, Zhou B, Schultz RM, Baldwin HS. Inner cell mass-specific expression of a cell adhesion molecule (PECAM-1/CD31) in the mouse blastocyst. Dev Biol, 2001; 234:317-29.
  • Shamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, Donovan PJ, Blumenthal PD, Huggins GR, Gearhart JD. Derivation of pluripotent stem cells from cultured human primordial germ cells. Dev Biol, 1998; 95:13726-31.
  • Sims M, Fırst NL. Production of calves by transfer of nuclei from cultured inner cell mass cells. Proc of the Nati Acad of Sci, 1994; 91:6143-7.
  • Smith AG. Embryo derived stem cells: of mice and men. Annual Review of Cell and Dev Biol, 2001; 17:435-62.
  • Soria B, Roche E. Berna G. Leon Quinto T, Reig JA, Martin F. Insulin secreting cells derived from embryonic stem cells derived from embryonic stem cells normalize glycemia in streotozotocin induced diabetic mice. Diabetes, 2000; 49:157-62.
  • Sökmensüer LK, 2007. Embriyonik kök hücre- ler ve tedavi amaçlı kullanımları. Hacettepe Tıp Dergisi, 38: 15-9.
  • Stewart R, Stojkovic M, Lako M. Mechanisms of self-renewal in human embryonic stem cells. Eur Jour Cancer, 2006; 42(9):1257-72.
  • Stice SL, Strelchenko NS, Keefer CL, Matthews L. Pluripotent bovine embryonic cell lines direct embryonic development following nuclear transfer. Bio of Repro, 1996; 54:100- 110.
  • Stojkovic P, Lako M, Stewart R, Przyborski S, Amstrong L, Evans J, Murdoch A, Strachan T, Stojkovic M. An autogeneic feeder cell system that undifferndiated human embryonic stem cells. Stem Cells, 2005; 23:306-14. growth of
  • Şenel F. Kök hücreler. Bilim ve Teknik Dergisi Şubat (eki), 2002; 1-15.
  • Thomson JA, Kalishman J, Golos TG, Dur- ning M, Harris CP, Becker R,A, Hearn JP. Isolation of a primate embryonic stem cell line. Dev Biol, 1995; 92:7844-8.
  • Thomson JA, Itskovitz EJ, Sharipo SS, Vaknitz MA, Swiergiel JJ, Marshall VS, Jones JM. Embryonic stem cell lines derived from human blastocysts. Science, 1998; 282 (5391):1145-7.
  • Türkşen K. İnsan embriyonik kök hücreleri izolasyon, idame ve farklılaşma (diferensiyasyon). Türk Hematoloji Derneği 9. Mezuniyet Sonrası Eğitim Bursu, 2006; 9-15.
  • Ural AU. Kök hücreler. Türk Ortopedi ve Travmatoloji Derneği Dergisi, 2006; 5(3- 4):140-5.
  • Ural AU. Embriyonel ve mezodermal kök hüc- reler, Türk Hematoloji Derneği. Erişim adresi: http://www.thd.org.tr/doc/ kurs_pdf/29_04_2006_ali_ugur_ural_10- 30_11-00.pdf 2006. Erişim tarihi: 27.06.2008. 39. Van
  • Stekelenburg-Harmers AE, Van
  • Achterberg TA, Rebel HG, Flechon JE,
  • Camphell KH, Weima SM, Mummery Cl.
  • Isolation and characterization of permanent
  • cell lines from inner cell mass cells of bovine
  • blastocysts. Mol Reprod Dev, 1995; 40(4):444 -54.
  • Verfaillie CM, Pera MF, Landsrop PM. Stem Cells Hype and Reality, Hematology Am Soc Hem Edu Program, 2002; 369-91.
  • Wang G, Zhang Y, Zhao Y, Li J, Cai J, Wang P, Meng S, Feng J, Miao C, Ding M, Li D, Deng H. Noggin and bFGF cooperate to maintain the pluripotency of human embryonic stem cells in the absence of feeder layers. Biochem Biophys Res Commun, 2005; 330 (3):934-42.
  • Wang L, Duan E, Sung LY, Jeong BS, Yang X, Tian XC. Generation and characterization of pluripotent stem cells from cloned bovine embryos. Biol Reprod, 2005; DOI:10.1095.

Embriyonik Kök Hücreler

Year 2012, Volume: 9 Issue: 1, 65 - 71, 01.03.2012

T. Karaşahin

Abstract

Embriyonik kök hücre, embriyoda erken evrede bulunan totipotent kök hücreler olarak tanımlanırlar. Embriyonik kök hücreler, erken embriyonik dönemde inner cell mass (ICM) kısmından elde edilir ve in vitro olarak bütün somatik hücrelere dönüşebilme yeteneği vardır. Embriyonik kök hücreler sınırsız olarak çoğalabilme kabiliyetlerinden dolayı diyabet, miyokart enfarktüsü ve parkinson gibi hemen hemen bütün dejeneratif ve hasar görmüş dokuların yenilenmesinde kullanılabilmektedir

Keywords

Embriyonik kök hücreler kök hücreler

References

  • Amit M, Margulets V, Segev H, Shariki K, Laevsky I, Coleman R, Elder J. Human feeder layers for human embryonic stem cells. Biol Reprod, 2004; 70:837-45.
  • Baran ÖP, Nergiz Y, Bahçeci S. Göbek kordo- nu kan ve stromal kökenli hücrelerin sinir hüc- relerine farklılaşması. Dicle Tıp Dergisi, 2007; 34:233-8.
  • Beksaç M, Çörtoğlu S, Kansu E, Öztürk M. Kök hücre araştırmalarında güncel kavramlar. Türkiye Bilimler Akademisi Raporları, 2004; sayı:7.
  • Bjorklund LM, Sanchez-Pernaute R, Chung S, Andersson T, Chen IY, McNaught KS, Brownell AL, Jenkins BG, Wahlestedt C, Kim KS, Icasson O. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a parkinson rat model. Proc Nath Acad Sci, 2002; 99:2344-9.
  • Chambers I, Smith A. Self- renewal of teratocarcinoma and embryonic stem cells. Oncogene, 2004; 23(43):7150-60.
  • Chung Y, Klimanskaya I, Becker S, Li T, Maserati M, Lu SJ, Zdravkovic T, Ilic D, Genbacev O, Fisher S, Krtolica A, Lanza R. Human embryonic stem cell lines generated without embryo destruction. Cell Stem Cell Doi, 2008; 10.1016/j.stem. 2007.12.013.
  • Cibelli JB, Stice SL, Golueke PJ, Kane JJ, Jerry J, Blackwell C, Ponce de Lond FA, Robl JM. Cloned transgenic calves produced from nonquiescent fetal fibroblasts. Science 1998; 280(5367):1256-1258 (Abstract).
  • Doss MX, Koehler CI, Gissel C, Hescheler J, Sachinidis A. Embryonic stem cells: a promising tool for cell replacement therapy, J Cell Mol Med, 2004; 8, 4:465-73.
  • Evans MJ, Kaufman MH. Establishment in culture of pluripotent tail cells from mouse embryos. Nature, 1981; 292:154-6.
  • Graves KH, Moreadith RW. Derivation and characterization of putative pluripotential embryonic stem cells from preimplantation embryos. Mol Reprod Dev, 1993; 36:424-33.
  • Güneş AM. Kök hücre plastisitesi ve tıptaki kullanım alanları. Güncel Pediatri, 2005; 36- 42.
  • Hollands P. Differantiation of embryonic haematopoietic stem cells from mouse blastocyst growing in vitro. Development, 1987; 99: 69-76.
  • Hyslop LA, Stojkovic M, Armstrong L, Walter T, Stojkovic P, Przyborski S, Herbert M, Murdoch A, Strachan T, Lako M. Downregulation of NANOG induces differentiation of human embryonic stem cell extraembryonic lineages. Stem Cells, 2005; 23: 1035-43.
  • Kahraman S, Candan ZN. İnsan embriyonik kök hücreleri. Türkiye Klinikleri J Surg Med Sci, 2006; 43:21-5.
  • Kansu E. Kök hücre biyolojisi ve plastisitesin- de güncel kavramlar. ANKEM Dergisi, 2006; 20(ek-2):1-8.
  • Kawasaki H, Mizuseki K, Nishikawa S, Kaneko S, Kuwana Y, Nakanishi S, Nishikawa SI, Sasai Y. Induction of midbrain dopaminergic neurons from ES cells by stromal cell derived inducing activity. Neuron, 2000; 1(28):31-40.
  • Kutlay N, Gül RTB, Güven T, Sert G, Gün M, Erzik C. Kök hücre araştırmalarının etik ve hukuk boyutuna ilişkin rapor. Türkiye Biyoetik Derneği Kök Hücre Araştırmaları ve Uygula- maları Kurulu, 2009.
  • Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarsinoma. Stem Cells, 1981; 78(12):7634-8.
  • Matsui Y, Zsebo K, Hogan BLM. Derivation of pluripotential embryonic stem cells frommurine primordial germ cells in culture. Cell, 1992; 70(5): 841-847.
  • Mitalipova M, Beyhan Z, First NL. Pluripotency of bovine embryonic cell line derived from precompacting embryos. Cloning, 2001; 3 (2):59-67.
  • Moore KA, Ema H, Lemischka IR. In vitro maintenance of highly purified, transplantable hematopoietic. Stem Cells Blood, 1997; 89 (12) :4337-47.
  • Peura TT, Bosman A, Stojanov T. Derivation of human embryonic stem cell lines. Theriogenology, 2007; 67:32-42.
  • Richards M, Tan S, Fong CY, Biswas A, Chan WK, Bongso A. Comperative evaulation of various human feeders for prolonged undifferentiated growth of human embryonic stem cells. Stem Cells, 2003; 21:546-56.
  • Robson P, Stein P, Zhou B, Schultz RM, Baldwin HS. Inner cell mass-specific expression of a cell adhesion molecule (PECAM-1/CD31) in the mouse blastocyst. Dev Biol, 2001; 234:317-29.
  • Shamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, Donovan PJ, Blumenthal PD, Huggins GR, Gearhart JD. Derivation of pluripotent stem cells from cultured human primordial germ cells. Dev Biol, 1998; 95:13726-31.
  • Sims M, Fırst NL. Production of calves by transfer of nuclei from cultured inner cell mass cells. Proc of the Nati Acad of Sci, 1994; 91:6143-7.
  • Smith AG. Embryo derived stem cells: of mice and men. Annual Review of Cell and Dev Biol, 2001; 17:435-62.
  • Soria B, Roche E. Berna G. Leon Quinto T, Reig JA, Martin F. Insulin secreting cells derived from embryonic stem cells derived from embryonic stem cells normalize glycemia in streotozotocin induced diabetic mice. Diabetes, 2000; 49:157-62.
  • Sökmensüer LK, 2007. Embriyonik kök hücre- ler ve tedavi amaçlı kullanımları. Hacettepe Tıp Dergisi, 38: 15-9.
  • Stewart R, Stojkovic M, Lako M. Mechanisms of self-renewal in human embryonic stem cells. Eur Jour Cancer, 2006; 42(9):1257-72.
  • Stice SL, Strelchenko NS, Keefer CL, Matthews L. Pluripotent bovine embryonic cell lines direct embryonic development following nuclear transfer. Bio of Repro, 1996; 54:100- 110.
  • Stojkovic P, Lako M, Stewart R, Przyborski S, Amstrong L, Evans J, Murdoch A, Strachan T, Stojkovic M. An autogeneic feeder cell system that undifferndiated human embryonic stem cells. Stem Cells, 2005; 23:306-14. growth of
  • Şenel F. Kök hücreler. Bilim ve Teknik Dergisi Şubat (eki), 2002; 1-15.
  • Thomson JA, Kalishman J, Golos TG, Dur- ning M, Harris CP, Becker R,A, Hearn JP. Isolation of a primate embryonic stem cell line. Dev Biol, 1995; 92:7844-8.
  • Thomson JA, Itskovitz EJ, Sharipo SS, Vaknitz MA, Swiergiel JJ, Marshall VS, Jones JM. Embryonic stem cell lines derived from human blastocysts. Science, 1998; 282 (5391):1145-7.
  • Türkşen K. İnsan embriyonik kök hücreleri izolasyon, idame ve farklılaşma (diferensiyasyon). Türk Hematoloji Derneği 9. Mezuniyet Sonrası Eğitim Bursu, 2006; 9-15.
  • Ural AU. Kök hücreler. Türk Ortopedi ve Travmatoloji Derneği Dergisi, 2006; 5(3- 4):140-5.
  • Ural AU. Embriyonel ve mezodermal kök hüc- reler, Türk Hematoloji Derneği. Erişim adresi: http://www.thd.org.tr/doc/ kurs_pdf/29_04_2006_ali_ugur_ural_10- 30_11-00.pdf 2006. Erişim tarihi: 27.06.2008. 39. Van
  • Stekelenburg-Harmers AE, Van
  • Achterberg TA, Rebel HG, Flechon JE,
  • Camphell KH, Weima SM, Mummery Cl.
  • Isolation and characterization of permanent
  • cell lines from inner cell mass cells of bovine
  • blastocysts. Mol Reprod Dev, 1995; 40(4):444 -54.
  • Verfaillie CM, Pera MF, Landsrop PM. Stem Cells Hype and Reality, Hematology Am Soc Hem Edu Program, 2002; 369-91.
  • Wang G, Zhang Y, Zhao Y, Li J, Cai J, Wang P, Meng S, Feng J, Miao C, Ding M, Li D, Deng H. Noggin and bFGF cooperate to maintain the pluripotency of human embryonic stem cells in the absence of feeder layers. Biochem Biophys Res Commun, 2005; 330 (3):934-42.
  • Wang L, Duan E, Sung LY, Jeong BS, Yang X, Tian XC. Generation and characterization of pluripotent stem cells from cloned bovine embryos. Biol Reprod, 2005; DOI:10.1095.
There are 47 citations in total.

Details

Primary Language Turkish
Authors

T. Karaşahin This is me

Submission Date June 24, 2014
Publication Date March 1, 2012
Published in Issue Year 2012 Volume: 9 Issue: 1

Cite

APA Karaşahin, T. (2012). Embriyonik Kök Hücreler. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, 9(1), 65-71.
AMA Karaşahin T. Embriyonik Kök Hücreler. Erciyes Üniversitesi Veteriner Fakültesi Dergisi. March 2012;9(1):65-71.
Chicago Karaşahin, T. “Embriyonik Kök Hücreler”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 9, no. 1 (March 2012): 65-71.
EndNote Karaşahin T (March 1, 2012) Embriyonik Kök Hücreler. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 9 1 65–71.
IEEE T. Karaşahin, “Embriyonik Kök Hücreler”, Erciyes Üniversitesi Veteriner Fakültesi Dergisi, vol. 9, no. 1, pp. 65–71, 2012.
ISNAD Karaşahin, T. “Embriyonik Kök Hücreler”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 9/1 (March2012), 65-71.
JAMA Karaşahin T. Embriyonik Kök Hücreler. Erciyes Üniversitesi Veteriner Fakültesi Dergisi. 2012;9:65–71.
MLA Karaşahin, T. “Embriyonik Kök Hücreler”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, vol. 9, no. 1, 2012, pp. 65-71.
Vancouver Karaşahin T. Embriyonik Kök Hücreler. Erciyes Üniversitesi Veteriner Fakültesi Dergisi. 2012;9(1):65-71.