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Toxoplasma gondii'li koyunlarda Oksidatif Stresin Glutatyon, Malondialdehit Düzeyi, Oksidatif Stres İndeksi, Toplam Oksidan Durumu ve Toplam Antioksidan Kapasitesi Kullanılarak Değerlendirilmesi

Year 2022, Volume: 19 Issue: 3, 182 - 188, 01.12.2022
https://doi.org/10.32707/ercivet.1204263

Abstract

Bu çalışma, Toxoplasma gondii (T. gondii) ile doğal olarak enfekte olmuş koyunlarda malondialdehit (MDA), gluta- tyon (GSH), toplam oksidan durumu (TOS), toplam antioksidan (TAK) kapasite ve oksidatif stres indeksi (OSI) gibi belirteçler kullanılarak oksidatif stresi değerlendirmek amacıyla yapıldı. Bu çalışmada toplam 30 baş Morkaraman ırkı koyun kullanıldı. Kontrol için 10 sağlıklı koyundan ve T. gondiiile doğal olarak enfekte olmuş 20 koyundan kan örnekleri alındı. Serum örneklerinde MDA, GSH, TOS ve TAK seviyeleri belirlendi. Serum TOS’ un TAK seviyelerine oranı OSI olarak değerlendirildi. T. gondii ile doğal olarak enfekte olan koyunlarda serum MDA düzeyi önemli ölçüde artarken (P<0.01), serum TAK ve TOS düzeyleri önemli ölçüde azaldı (P<0.01). Serum GSH ve OSI düzeyleri yönünden gruplar arasında farklılık bulunamadı (P˃0.05). T. gondiiile doğal enfekte koyunlarda TAK ile OSI arasında negatif (P<0.01), TOS ile MDA arasında ise pozitif (P<0.01) korelasyon saptandı. Sonuç olarak T. gondiiile doğal enfekte koyunlarda OSI, MDA ve TAK değerlerinin oksidatif stres göstergesi olarak kullanılabileceği tespit edildi.

References

  • Aktas MS, Kandemir FM, Kirbas A, Hanedan B, Ay- din MA. Evaluation of oxidative stress in sheep infected with Psoroptes ovis using total antioxidant capacity, total oxidant status, and malondialdehyde level. J Vet Res 2017; 61(2): 197-201.
  • Ali WK, Umar FH, Aziz BN. Effect of Toxoplasma gondii infestation on lipid peroxidation and certain antioxidants in pregnant women in Mosul city. RJS 2006; 17(11): 16-25.
  • Atakisi O, Oral H, Atakisi E, Merhan O, Pancarci SM, Ozcan A, Marasli S, Polat B, Colak A, Kaya S. Subclinical mastitis causes alterations in nitric oxide, total oxidant and antioxidant capacity in cow milk. Res Vet Sci 2010; 89(1): 10-3.
  • Atmaca N, Cınar M, Güner B, Kabakçı R, Gazyagcı AN, Atmaca HT, Canpolat S. Evaluation of oxidative stress, hematological and biochemical parameters during Toxoplasma gondii infection in gerbils. Ankara Üniv Vet Fak Derg 2015; 62(3):165-70.
  • Aytekin I, Aksit H, Sait A, Kaya F, Aksit D, Gökmen M, Baca AU. Evaluation of oxidative stress via total antioxidant status, sialic acid, malondialdehyde and RT-PCR findings in sheep affected with blue- tongue. Vet Rec Open 2015; 2(1): e000054.
  • Baghshani H, Razmi GR, Yaghfouri S, Ahmadi A. Status of some oxidative stress biomarkers in sheep naturally infected with theileriosis. Res Opin Anim Vet Sci 2011; 1: 499-504.
  • Bahrami S, Shahriari A, Tavalla M, Azadmanesh S, Hamidinejat H. Blood levels of oxidant/antioxidant parameters in rats infected with Toxoplasma gondii. Oxid 2016; 8045969.
  • Baltacıoğlu E,Yuva P, Aydın G, Alver A, Kahraman C, Karabulut E, Akalın F. Lipid peroxidation levels and total oxidant/antioxidant status in serum and saliva from patients with chronic and aggressive periodontitis. Oxidative stress index: A new bi- omarker for periodontal disease? J Periodontol 2014; 85(10): 1432-41.
  • Baptistiolli L, Narciso LG, Almeida BFM, Bosco AM, Souza JC, Torrecilha RBP, Pereira PP, Figueiredo RN, Garcia JF, Kaneto CN, Ciarlini PC. Systemic oxidative stress in Suffolk and Santa Ines sheep experimentally infected with Haemonchus contor- tus. Acta Parasitol 2018; 63(3): 504-14.
  • Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O. Oxidative stress and antioxidant de- fense. World Allergy Organ J 2012; 5(1): 9.
  • Celi P. The role of oxidative stress in small ruminants' health and production. R Bras Zootec 2010; 39: 348-63.
  • Celi P, Gabai G. Oxidant/antioxidant balance in ani- mal nutrition and health: The role of protein oxida- tion. Front Vet Sci 2015; 2: 48.
  • Duncanson P, Terry RS, Smith JE, Hide G. High lev- els of congenital transmission of Toxoplasma gondii in a commercial sheep flock. Int J Parasitol 2001; 31(14): 1699-703.
  • Durgut R, Ataseven VS, Sagkan-Ozturk A, Ozturk OH. Evaluation of total oxidative stress and total antioxidant status in cows with natural bovine her- pesvirus-1 infection. J Anim Sci 2013; 91(7): 3408- 12.
  • Durgut R, Ozturk AS, Ozturk OH, Guzel M. Evalua- tion of oxidative stress, antioxidant status and lipid profile in cattle with displacement of the abomasum. Ankara Üniv Vet Fak Derg 2016; 63(2): 137- 41.
  • El-Sokkary GH, Omar HM, Hassanein AFMM, Cuzzo- crea S, Reiter RJ. Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni. Free Radic Biol Med 2002; 32(4): 319-32.
  • Engin AB, Dogruman-Al F, Ercin U, Celebi B, Babur C, Bukan N. Oxidative stress and tryptophan deg- radation pattern of acute Toxoplasma gondii infection in mice. Parasitol Res 2012; 111(4): 1725-30.
  • Erel O. A novel automated direct measurement meth- od for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Bio- chem 2004; 37(4): 277-85.
  • Erel O. A new automated colorimetric method for measuring total oxidant status. Clin Biochem 2005; 38(12): 1103-11.
  • Esmaeilnejad B, Tavassoli M, Asri-Rezaei S, Dalir- Naghadeh B, Malekinejad H, Jalilzadeh-Amin G, Arjmand J, Golabi M, Hajipour N. Evaluation of antioxidant status, oxidative stress and serum trace mineral levels associated with Babesia ovis para- sitemia in sheep. Vet Parasitol 2014; 205(1-2): 38- 45.
  • Gao Y, Guo H, Moumouni AP, Sun M, Liu M, Efstra- tiou A, Lee S, Wang G, Li J, Li Y. Seroprevalence of Toxoplasma gondii infection in sheep from north- ern China. Trop Biomed 2018; 35(3): 664-8.
  • Ghiselli A, Serafini M, Natella F, Scaccini C. Total antioxidant capacity as a tool to assess redox sta- tus: Critical view and experimental data. Free Radic Biol Med 2000; 29(11): 1106-14.
  • Heidarpour M, Mohri M, Borji H, Moghaddas E. Oxi- dant/antioxidant balance and trace elements status in sheep with liver cystic echinococcosis. Comp Clin Path 2013a; 22(6): 1043-9.
  • Heidarpour M, Mohri M, Borji H, Moghdass E. Oxi- dant/antioxidant status in cattle with liver cystic echinococcosis. Vet Parasitol 2013b; 195(1-2): 131 -5.
  • Innes EA, Bartley PM, Buxton D, Katzer F. Ovine toxoplasmosis. Parasitology 2009; 136(14): 1887- 94.
  • Invernizzi G, Koutsouli P, Savoini G, Mariani E, Re- bucci R, Politis ABI. Oxidative indices as metabolic stress predictors in periparturient dairy cows. Ital J Anim Sci 2019; 18(1): 1356-60.
  • Jafari M, Salehi M, Shirbazou S, Abasian L, Talebi- Meymand F. Evaluation of gender-related differences in response to oxidative stress in Toxoplasma gondii positive serum. Ann Mil Health Sci Res 2014; 12(2): 64-9.
  • Karabulut H, Gülay MŞ. Antioksidanlar. MAE Vet Fak Derg 2016; 1(1): 65-76.
  • Karaman U, Celik T, Kiran TR, Colak C, Daldal NU. Malondialdehyde, glutathione, and nitric oxide lev- els in Toxoplasma gondii seropositive patients. Korean J Parasitol 2008; 46(4): 293.
  • Kirmizigul AH, Ogun M, Ozen H, Erkilic EE, Gokce E, Karaman M, Kukurt A. Oxidative stress and total sialic acid levels in sheep naturally infected with pox virus. Pak Vet J 2016; 36(3): 312-5.
  • Kolodziejczyk L, Siemieniuk E, Skrzydlewska E. Anti- oxidant potential of rat liver in experimental infec- tion with Fasciola hepatica. Parasitol Res 2005; 96 (6): 367-72.
  • Kosecik M, Erel O, Sevinc E, Selek S. Increased oxi- dative stress in children exposed to passive smok- ing. Int J Cardiol 2005; 100(1): 61-4.
  • Kükürt A, Ögün M, Merhan O, Kaya İ, Akyüz E, Kara- pehlivan M. Oxidative stress index in Tuj sheep with pneumonia. J Cell Neurosci Oxid Stress 2018; 10(2): 755.
  • Luberda Z. The role of glutathione in mammalian gametes. Reprod Biol 2005; 5(1): 5-17.
  • Macun HC, Çınar M, Azkur AK, Kalender H, Erat S. Oxidative stress in Akkaraman ewes with seroposi- tive for schmallenberg virus. Atatürk University J Vet Sci 2018; 13(2): 128-34.
  • Martha A, Sánchez R, Víctor MMN. Oxidative stress indexes for diagnosis of health or disease in humans. Oxid Med Cell Longev 2019; 25: 4128152.
  • Mor N, Arslan MÖ. Kars yöresindeki koyunlarda Tox- oplasma gondii’nin seroprevalansı. Kafkas Univ Vet Fak Derg 2007; 13(2): 165-70.
  • Mutlu B, Aksoy N, Cakir H, Celik H, Erel O. The effects of the mode of delivery on oxidative– antioxidative balance. J Matern Fetal Neonatal Med 2011; 24(11): 1367-70.
  • Neelam, Kumar P, Virmani M, Rakha NK, Jhambh R. The interplay of oxidants and antioxidants: Oxidative stress in bovine tropical theileriosis. Int J Pure App Biosci 2017; 5(5): 1478-84.
  • Ohkawa H, Ohishi N, Yagi K. Assay for lipid perox- ides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95(2): 351-8.
  • Oncel T, Vural G. Occurrence of Toxoplasma gondii antibodies in sheep in Istanbul, Turkey. Vet Arh 2006; 76(6): 547-53.
  • Ragozo AMA, Yai LEO, Oliveira L, Dias RA, Dubey J, Gennari SM. Seroprevalence and isolation of Toxoplasma gondii from sheep from São Paulo state. Brazil J Parasitol 2008; 94(6): 1259-63.
  • Saleh MA. Circulating oxidative stress status in desert sheep naturally infected with Fasciola hepatica. Vet Parasitol 2008; 15(3-4): 262-9.
  • Saleh MA, Al-Salahy MB, Sanousi SA. Oxidative stress in blood of camels (Camelus dromedaries) naturally infected with Trypanosoma evansi. Vet Parasitol 2009; 162(3-4): 192-9. Sanchez-Campos S, Tunon M, Gonzalez P, Gonza- lez-Gallego J. Oxidative stress and changes in liver antioxidant enzymes induced by experimental dicroceliosis in hamsters. Parasitol Res 1999; 85(6): 468-74.
  • Sedlak J, Lindsay RHL. Estimation of total, and nonprotein sulfhydryl groups in tissue with Elman’s reagent. Anal Biochem 1968; 25: 192-205.
  • Sezer K, Keskin M. Serbest oksijen radikallerinin hastaliklarin patogenezisindeki rolü. FÜ Sağ Bil Vet Derg 2014; 28(1): 49-56.
  • Sies H. Oxidative stress: Oxidants and antioxidants. Exp Physiol 1997; 82(2): 291-5.
  • Şimşek S, Yüce A, Ütük AE. Determination of serum malondialdehyde levels in sheep naturally infected with Dicrocoelium dendriticum. FÜ Sağlık Bil Dergisi 2006; 20(3): 217-20.
  • Süleyman H, Gul V, Erhan E. Oksidatif stres ve doku hasarı. Erzincan Tıp Dergisi 2018; 1(1): 1-4.
  • Van Der Puije WN, Bosompem KM, Canacoo EA, Wastling JM, Akanmori BD. The prevalence of anti- Toxoplasma gondii antibodies in Ghanaian sheep and goats. Acta Trop 2000; 76(1): 21-6.
  • Yilmaz S, Issi M, Kandemir FM, Gul Y. Malondialde- hyde and total antioxidant levels and hematological parameters of beef cattle with coccidiosis. Van Vet J 2014; 25(2): 41-5.

Evaluation of Oxidative Stress in Sheep with Toxoplasma gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers

Year 2022, Volume: 19 Issue: 3, 182 - 188, 01.12.2022
https://doi.org/10.32707/ercivet.1204263

Abstract

This study was conducted to evaluate oxidative stress using markers such as malondialdehyde (MDA), glu- tathione (GSH), total oxidant status (TOS), total antioxidant capacity (TAC) and oxidative stress index (OSI) in sheep naturally infected with Toxoplasma gondii (T. gondii). A total of 30 Morkaraman breed sheep were used in this study. Blood samples were obtained from 10 healthy control sheep and 20 sheep naturally infected with T. gondii. malondial- dehyde, GSH, TOS and TAC levels were determined in serum samples. The ratio of serum TOS to TAC levels was assessed as OSI. While the serum MDA level increased significantly (P<0.01), the serum TAC and TOS levels de- creased significantly (P<0.01) in naturally infected with T. gondii sheep. There were no different for serum GSH and OSI in between the groups (P˃0.05). Negative correlation (P<0.01) between TAC and OSI and a positive correlation (P<0.01) between TOS and MDA were determined in naturally infected with T. gondii sheep. In conclusion, the results of study suggested that OSI, TAC and MDA could be used as indicator of oxidative stress for sheep naturally infected with T. gondii.

References

  • Aktas MS, Kandemir FM, Kirbas A, Hanedan B, Ay- din MA. Evaluation of oxidative stress in sheep infected with Psoroptes ovis using total antioxidant capacity, total oxidant status, and malondialdehyde level. J Vet Res 2017; 61(2): 197-201.
  • Ali WK, Umar FH, Aziz BN. Effect of Toxoplasma gondii infestation on lipid peroxidation and certain antioxidants in pregnant women in Mosul city. RJS 2006; 17(11): 16-25.
  • Atakisi O, Oral H, Atakisi E, Merhan O, Pancarci SM, Ozcan A, Marasli S, Polat B, Colak A, Kaya S. Subclinical mastitis causes alterations in nitric oxide, total oxidant and antioxidant capacity in cow milk. Res Vet Sci 2010; 89(1): 10-3.
  • Atmaca N, Cınar M, Güner B, Kabakçı R, Gazyagcı AN, Atmaca HT, Canpolat S. Evaluation of oxidative stress, hematological and biochemical parameters during Toxoplasma gondii infection in gerbils. Ankara Üniv Vet Fak Derg 2015; 62(3):165-70.
  • Aytekin I, Aksit H, Sait A, Kaya F, Aksit D, Gökmen M, Baca AU. Evaluation of oxidative stress via total antioxidant status, sialic acid, malondialdehyde and RT-PCR findings in sheep affected with blue- tongue. Vet Rec Open 2015; 2(1): e000054.
  • Baghshani H, Razmi GR, Yaghfouri S, Ahmadi A. Status of some oxidative stress biomarkers in sheep naturally infected with theileriosis. Res Opin Anim Vet Sci 2011; 1: 499-504.
  • Bahrami S, Shahriari A, Tavalla M, Azadmanesh S, Hamidinejat H. Blood levels of oxidant/antioxidant parameters in rats infected with Toxoplasma gondii. Oxid 2016; 8045969.
  • Baltacıoğlu E,Yuva P, Aydın G, Alver A, Kahraman C, Karabulut E, Akalın F. Lipid peroxidation levels and total oxidant/antioxidant status in serum and saliva from patients with chronic and aggressive periodontitis. Oxidative stress index: A new bi- omarker for periodontal disease? J Periodontol 2014; 85(10): 1432-41.
  • Baptistiolli L, Narciso LG, Almeida BFM, Bosco AM, Souza JC, Torrecilha RBP, Pereira PP, Figueiredo RN, Garcia JF, Kaneto CN, Ciarlini PC. Systemic oxidative stress in Suffolk and Santa Ines sheep experimentally infected with Haemonchus contor- tus. Acta Parasitol 2018; 63(3): 504-14.
  • Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O. Oxidative stress and antioxidant de- fense. World Allergy Organ J 2012; 5(1): 9.
  • Celi P. The role of oxidative stress in small ruminants' health and production. R Bras Zootec 2010; 39: 348-63.
  • Celi P, Gabai G. Oxidant/antioxidant balance in ani- mal nutrition and health: The role of protein oxida- tion. Front Vet Sci 2015; 2: 48.
  • Duncanson P, Terry RS, Smith JE, Hide G. High lev- els of congenital transmission of Toxoplasma gondii in a commercial sheep flock. Int J Parasitol 2001; 31(14): 1699-703.
  • Durgut R, Ataseven VS, Sagkan-Ozturk A, Ozturk OH. Evaluation of total oxidative stress and total antioxidant status in cows with natural bovine her- pesvirus-1 infection. J Anim Sci 2013; 91(7): 3408- 12.
  • Durgut R, Ozturk AS, Ozturk OH, Guzel M. Evalua- tion of oxidative stress, antioxidant status and lipid profile in cattle with displacement of the abomasum. Ankara Üniv Vet Fak Derg 2016; 63(2): 137- 41.
  • El-Sokkary GH, Omar HM, Hassanein AFMM, Cuzzo- crea S, Reiter RJ. Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni. Free Radic Biol Med 2002; 32(4): 319-32.
  • Engin AB, Dogruman-Al F, Ercin U, Celebi B, Babur C, Bukan N. Oxidative stress and tryptophan deg- radation pattern of acute Toxoplasma gondii infection in mice. Parasitol Res 2012; 111(4): 1725-30.
  • Erel O. A novel automated direct measurement meth- od for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Bio- chem 2004; 37(4): 277-85.
  • Erel O. A new automated colorimetric method for measuring total oxidant status. Clin Biochem 2005; 38(12): 1103-11.
  • Esmaeilnejad B, Tavassoli M, Asri-Rezaei S, Dalir- Naghadeh B, Malekinejad H, Jalilzadeh-Amin G, Arjmand J, Golabi M, Hajipour N. Evaluation of antioxidant status, oxidative stress and serum trace mineral levels associated with Babesia ovis para- sitemia in sheep. Vet Parasitol 2014; 205(1-2): 38- 45.
  • Gao Y, Guo H, Moumouni AP, Sun M, Liu M, Efstra- tiou A, Lee S, Wang G, Li J, Li Y. Seroprevalence of Toxoplasma gondii infection in sheep from north- ern China. Trop Biomed 2018; 35(3): 664-8.
  • Ghiselli A, Serafini M, Natella F, Scaccini C. Total antioxidant capacity as a tool to assess redox sta- tus: Critical view and experimental data. Free Radic Biol Med 2000; 29(11): 1106-14.
  • Heidarpour M, Mohri M, Borji H, Moghaddas E. Oxi- dant/antioxidant balance and trace elements status in sheep with liver cystic echinococcosis. Comp Clin Path 2013a; 22(6): 1043-9.
  • Heidarpour M, Mohri M, Borji H, Moghdass E. Oxi- dant/antioxidant status in cattle with liver cystic echinococcosis. Vet Parasitol 2013b; 195(1-2): 131 -5.
  • Innes EA, Bartley PM, Buxton D, Katzer F. Ovine toxoplasmosis. Parasitology 2009; 136(14): 1887- 94.
  • Invernizzi G, Koutsouli P, Savoini G, Mariani E, Re- bucci R, Politis ABI. Oxidative indices as metabolic stress predictors in periparturient dairy cows. Ital J Anim Sci 2019; 18(1): 1356-60.
  • Jafari M, Salehi M, Shirbazou S, Abasian L, Talebi- Meymand F. Evaluation of gender-related differences in response to oxidative stress in Toxoplasma gondii positive serum. Ann Mil Health Sci Res 2014; 12(2): 64-9.
  • Karabulut H, Gülay MŞ. Antioksidanlar. MAE Vet Fak Derg 2016; 1(1): 65-76.
  • Karaman U, Celik T, Kiran TR, Colak C, Daldal NU. Malondialdehyde, glutathione, and nitric oxide lev- els in Toxoplasma gondii seropositive patients. Korean J Parasitol 2008; 46(4): 293.
  • Kirmizigul AH, Ogun M, Ozen H, Erkilic EE, Gokce E, Karaman M, Kukurt A. Oxidative stress and total sialic acid levels in sheep naturally infected with pox virus. Pak Vet J 2016; 36(3): 312-5.
  • Kolodziejczyk L, Siemieniuk E, Skrzydlewska E. Anti- oxidant potential of rat liver in experimental infec- tion with Fasciola hepatica. Parasitol Res 2005; 96 (6): 367-72.
  • Kosecik M, Erel O, Sevinc E, Selek S. Increased oxi- dative stress in children exposed to passive smok- ing. Int J Cardiol 2005; 100(1): 61-4.
  • Kükürt A, Ögün M, Merhan O, Kaya İ, Akyüz E, Kara- pehlivan M. Oxidative stress index in Tuj sheep with pneumonia. J Cell Neurosci Oxid Stress 2018; 10(2): 755.
  • Luberda Z. The role of glutathione in mammalian gametes. Reprod Biol 2005; 5(1): 5-17.
  • Macun HC, Çınar M, Azkur AK, Kalender H, Erat S. Oxidative stress in Akkaraman ewes with seroposi- tive for schmallenberg virus. Atatürk University J Vet Sci 2018; 13(2): 128-34.
  • Martha A, Sánchez R, Víctor MMN. Oxidative stress indexes for diagnosis of health or disease in humans. Oxid Med Cell Longev 2019; 25: 4128152.
  • Mor N, Arslan MÖ. Kars yöresindeki koyunlarda Tox- oplasma gondii’nin seroprevalansı. Kafkas Univ Vet Fak Derg 2007; 13(2): 165-70.
  • Mutlu B, Aksoy N, Cakir H, Celik H, Erel O. The effects of the mode of delivery on oxidative– antioxidative balance. J Matern Fetal Neonatal Med 2011; 24(11): 1367-70.
  • Neelam, Kumar P, Virmani M, Rakha NK, Jhambh R. The interplay of oxidants and antioxidants: Oxidative stress in bovine tropical theileriosis. Int J Pure App Biosci 2017; 5(5): 1478-84.
  • Ohkawa H, Ohishi N, Yagi K. Assay for lipid perox- ides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95(2): 351-8.
  • Oncel T, Vural G. Occurrence of Toxoplasma gondii antibodies in sheep in Istanbul, Turkey. Vet Arh 2006; 76(6): 547-53.
  • Ragozo AMA, Yai LEO, Oliveira L, Dias RA, Dubey J, Gennari SM. Seroprevalence and isolation of Toxoplasma gondii from sheep from São Paulo state. Brazil J Parasitol 2008; 94(6): 1259-63.
  • Saleh MA. Circulating oxidative stress status in desert sheep naturally infected with Fasciola hepatica. Vet Parasitol 2008; 15(3-4): 262-9.
  • Saleh MA, Al-Salahy MB, Sanousi SA. Oxidative stress in blood of camels (Camelus dromedaries) naturally infected with Trypanosoma evansi. Vet Parasitol 2009; 162(3-4): 192-9. Sanchez-Campos S, Tunon M, Gonzalez P, Gonza- lez-Gallego J. Oxidative stress and changes in liver antioxidant enzymes induced by experimental dicroceliosis in hamsters. Parasitol Res 1999; 85(6): 468-74.
  • Sedlak J, Lindsay RHL. Estimation of total, and nonprotein sulfhydryl groups in tissue with Elman’s reagent. Anal Biochem 1968; 25: 192-205.
  • Sezer K, Keskin M. Serbest oksijen radikallerinin hastaliklarin patogenezisindeki rolü. FÜ Sağ Bil Vet Derg 2014; 28(1): 49-56.
  • Sies H. Oxidative stress: Oxidants and antioxidants. Exp Physiol 1997; 82(2): 291-5.
  • Şimşek S, Yüce A, Ütük AE. Determination of serum malondialdehyde levels in sheep naturally infected with Dicrocoelium dendriticum. FÜ Sağlık Bil Dergisi 2006; 20(3): 217-20.
  • Süleyman H, Gul V, Erhan E. Oksidatif stres ve doku hasarı. Erzincan Tıp Dergisi 2018; 1(1): 1-4.
  • Van Der Puije WN, Bosompem KM, Canacoo EA, Wastling JM, Akanmori BD. The prevalence of anti- Toxoplasma gondii antibodies in Ghanaian sheep and goats. Acta Trop 2000; 76(1): 21-6.
  • Yilmaz S, Issi M, Kandemir FM, Gul Y. Malondialde- hyde and total antioxidant levels and hematological parameters of beef cattle with coccidiosis. Van Vet J 2014; 25(2): 41-5.
There are 51 citations in total.

Details

Primary Language English
Journal Section Articles
Authors

Nergis Ulaş This is me 0000-0003-2340-6882

Mustafa Sinan Aktaş This is me 0000-0002-7206-5757

Kerim Emre Yanar This is me 0000-0001-7302-7077

Ömer Aydın This is me 0000-0001-9444-1904

Muhammed Sertaç Eroğlu This is me 0000-0003-1061-8421

Emre Eren This is me 0000-0003-3118-7384

Publication Date December 1, 2022
Submission Date March 9, 2022
Acceptance Date May 30, 2022
Published in Issue Year 2022 Volume: 19 Issue: 3

Cite

APA Ulaş, N., Aktaş, M. S., Yanar, K. E., Aydın, Ö., et al. (2022). Evaluation of Oxidative Stress in Sheep with Toxoplasma gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, 19(3), 182-188. https://doi.org/10.32707/ercivet.1204263
AMA Ulaş N, Aktaş MS, Yanar KE, Aydın Ö, Eroğlu MS, Eren E. Evaluation of Oxidative Stress in Sheep with Toxoplasma gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers. Erciyes Üniv Vet Fak Derg. December 2022;19(3):182-188. doi:10.32707/ercivet.1204263
Chicago Ulaş, Nergis, Mustafa Sinan Aktaş, Kerim Emre Yanar, Ömer Aydın, Muhammed Sertaç Eroğlu, and Emre Eren. “Evaluation of Oxidative Stress in Sheep With Toxoplasma Gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 19, no. 3 (December 2022): 182-88. https://doi.org/10.32707/ercivet.1204263.
EndNote Ulaş N, Aktaş MS, Yanar KE, Aydın Ö, Eroğlu MS, Eren E (December 1, 2022) Evaluation of Oxidative Stress in Sheep with Toxoplasma gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 19 3 182–188.
IEEE N. Ulaş, M. S. Aktaş, K. E. Yanar, Ö. Aydın, M. S. Eroğlu, and E. Eren, “Evaluation of Oxidative Stress in Sheep with Toxoplasma gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers”, Erciyes Üniv Vet Fak Derg, vol. 19, no. 3, pp. 182–188, 2022, doi: 10.32707/ercivet.1204263.
ISNAD Ulaş, Nergis et al. “Evaluation of Oxidative Stress in Sheep With Toxoplasma Gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 19/3 (December 2022), 182-188. https://doi.org/10.32707/ercivet.1204263.
JAMA Ulaş N, Aktaş MS, Yanar KE, Aydın Ö, Eroğlu MS, Eren E. Evaluation of Oxidative Stress in Sheep with Toxoplasma gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers. Erciyes Üniv Vet Fak Derg. 2022;19:182–188.
MLA Ulaş, Nergis et al. “Evaluation of Oxidative Stress in Sheep With Toxoplasma Gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, vol. 19, no. 3, 2022, pp. 182-8, doi:10.32707/ercivet.1204263.
Vancouver Ulaş N, Aktaş MS, Yanar KE, Aydın Ö, Eroğlu MS, Eren E. Evaluation of Oxidative Stress in Sheep with Toxoplasma gondii by Malondialdehyde, Glutathione Levels, Total Oxidant Status, Total Antioxidant Capacity and Oxidative Stress Index Markers. Erciyes Üniv Vet Fak Derg. 2022;19(3):182-8.