Langerhans Cell Histiocytosis in Bilateral Basis Mandibularis: A Rare Case

Abstract

Langerhans cell histiocytosis (LCH), an autoimmune disease, is a rare group of diseases characterized by abnormal proliferation of atypical histiocytes originating from the bone marrow. A 57-year-old male patient with no systemic disease applied to our clinic for consultation. The patient had mild pain in the bilateral mandible corpus and itching on the skin. CBCT examination revealed bilateral destruction areas on the mandible basis. No bone expansion and periosteal reaction were observed. The patient diagnosed with LCH was accepted as an eosinophilic granuloma variant since no extraskeletal extension was observed. This case report aims to present a rare case of LCH that destroyed the bilateral basis mandible. In addition, it is to present the radiographic data of this disease, in which dentists play an important role in early diagnosis since the first involvement area is usually the head and neck region.

Keywords

• Langerhans Hücre Histiyositozu
• eozinofilik granülom
• cone beam computer tomography

Bilateral Basis Mandibulariste görülen Langerhans Hücreli Histiyositozis: Nadir Bir Olgu

Abstract

Otoimmün bir hastalık olan Langerhans hücreli histiyositoz (LHH), kemik iliği kaynaklı atipik histiositlerin anormal proliferasyonu ile karakterize nadir görülen bir hastalık grubudur. Sistemik hastalığı olmayan 57 yaşında erkek hasta kliniğimize konsültasyon amacı ile başvurdu. Hastada bilateral mandibula korpusta hafif düzeyde ağrı ve deride kaşıntı şikayeti mevcuttu. KIBT incelemesinde mandibula alt sınırında baziste, bilateral yıkım alanları izlendi. Kemikte ekspansiyon ve periost reaksiyonu izlenmedi. LHH tanısı alan hastada ekstraskeletal yayılım görülmediğinden eozinofilik granülom varyantı olarak kabul edildi. Bu olgu sunumunun amacı, bilateral basis mandibulada yıkıma sebep olmuş nadir yerleşimli LHH olgusunu sunmaktır. Ayrıca ilk tutulum bölgesi genellikle baş ve boyun bölgesi olması nedeniyle diş hekimlerinin erken tanıda önemli rol aldığı bu hastalığın radyografik verilerini sunmaktır.

Keywords

• Langerhans Hücre Histiyositozu
• Konik Işınlı Bilgisayarlı Tomografi
• eozinofilik granülom

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