ADACAYI YAPRAKLARININ (SALVIA OFFICINALIS L.) KOLİNERJİK ETKİLERİ

Year 2014, , 275 - 281, 11.01.2015

Başar Altınterim

https://doi.org/10.18185/eufbed.25846

Abstract

Öğrenme, bellek ve dikkat gibi algısal işlevler ön beyin tabanındaki kolinerjik nöronlarla ilişkilidir. Ön beyin tabanındaki kolinerjik sistemin öğrenmedeki rolü çok tartışılmıştır. Yakın zamanlarda yapılan çalışmalar genel öğrenmede ve hafıza mekanizmasında ön beyin tabanındaki kolinerjik sisteminin etkin bir rolü olduğunu desteklemektedir. Salvia ofŞcinalis L. (adaçayı) yaprakları iyi bir antioksidan olarak bilinir. Beyin fonksiyon bozukluğu, kanser, kalp hastalıkları ve immün sistem zayıflığı, serbest radikallerin neden olduğu hücresel yıkım gibi çoğu dejeneratif hastalıklarda kullanımı tavsiye edilmektedir. Diyetle alınması hastalıkların engellenmesinde bir antioksidan olarak önemli bir rol oynayabilir

Keywords

Adaçayı, asetilkolin, kolinerjik etki

CHOLINERGIC EFFECTS OF SAGE (SALVIA OFFICINALIS L.) LEAVES

Abstract

The cholinergic basal forebrain (CBF) has been implicated in cognitive functions including learning, memory, and attention. The role of the basal forebrain cholinergic system in learning has been widely debated. Early studies are supported a role for the basal forebrain cholinergic system in general learning and memory mechanisms. The leaves of Salvia officinalis L. (sage) are well known for their antioxidative properties. There is increasing evidence to suggest that many degenerative diseases, such as brain dysfunction, cancer, heart diseases, and weakened immune system, could be the result of cellular damage caused by free radicals, and antioxidants present in human diet may play an important role in disease prevention.

Keywords

Sage, acetylcholine, cholinergic effect

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