Investigation of Production Cross-Sections by Fission Barrier Models of I-131 Radionuclide used in Cancer Treatment and Diagnosis
Abstract
The use of radioisotopes in the
diagnosis and treatment of cancer diseases is very important in medical
radiology. In radioisotope production, it is desirable that the reaction
efficiency is high and the production cost is low. In order to achieve these,
it is necessary to investigate theoretically the nuclear reactions in advance. In
this study, different production methods of 131I used in the diagnosis and
treatment of thyroid and kidney cancer were investigated. The possible
reactions for the production of 131I radioisotope by the (p, f) reactions were
theoretically examined. For theoretical studies, fission barrier models in
TALYS computer code were used. Each model was compared with each other and with
the experimental data obtained from EXFOR database.
Keywords
Cancer treatment 131I radioisotope cross-section Talys Exfor
References
- Büyükuslu, H., Kaplan, A., Tel, E., Yıldırım, G., Aydın, A., 2010, Production Cross Sections of Medical 110, 111In Radioisotopes, Kerntechnik 75 (3) 103-108.
- Capote, R., vd., 2009. RIPL – Reference Input Parameter Library for Calculation of Nuclear Reactions and Nuclear Data Evaluations. Nuclear Data Sheets 110. 3107–3214.
- Demir, B., Kaplan, A., Çapalı, V., Sarpün, İ. H., Aydın, A. and Tel, E., 2015, Production Cross–Section Calculations of Medical 32P, 117Sn, 153Sm and 186,188Re Radionuclides Used in Bone Pain Palliation Treatment, Kerntechnik 80 (1), 58-65.
- Gediklioğlu, A., 1988. Çekirdek Fiziğine Giriş. Karadeniz Teknik Üniversitesi Basımevi, Yayın No: 130, 220s. Trabzon.
- Gündoğdu E. A, Özgenç E., Ekinci M., Özdemir D., Aşıkoğlu M., 2018, Nükleer Tıpta Görüntüleme ve Tedavide Kullanılan Radyofarmasötikler, J. Lit. Pharm Sci., 7 (1) 24-34.
- Koning, A. J., Hilaire, S., Goriely S. 2018. “TALYS–1.9 A Nuclear Reaction Program, User Manual”, Nuclear Research and Consultancy Group (NRG), Netherlands.
- Krappe, H. J., Nix, J. R. Ve Sierk A.J., 1979. Unified Nuclear Potential For Heavy-İon Elastic Scattering, Fusion, Fission, and Ground-State Masses And Deformations. Phys. Rev. C20, 992.
- Mamdouh, A., Pearson, J.M., Raget, M. and Tondeur, F. 2001. Fission barriers of neutron–rich and superheavy nuclei calculated with the ETFSI method. Nuclear Physics A, 679: 337–358.
- NRDC-EXFOR (Experimental Nuclear Reaction Data File), Database Version of Mayıs 5, 2019. Brookhaven National Laboratory National Nuclear Data Centre. http://www.nndc.bnl.gov/nndc/exfor/. Son Erişim Tarihi: 05.04.2019.
- Tel, E., Aydın, A., Kara, A., Kaplan, A., 2012, Investigation of Ground State Features for Some Medical Radionuclides Using an effective Nuclear Force, Kerntechnik 77 (1) 50-55.
- World Healt Organization, Latest Global Cancer Data, The International Agency for Research on Cancer (IARC), France (September 12, 2018).
Kanser Tedavi ve Teşhisinde Kullanılan I-131 Radyoizotopun Fisyon Bariyer Modelleri Kullanılarak Üretim Tesir Kesitlerinin İncelenmesi
Abstract
Kanser hastalıklarının teşhis ve
tedavisinde radyoizotopların kullanılması tıbbi radyolojide oldukça önemlidir.
Radyoizotop üretiminde, reaksiyon veriminin yüksek ve üretim maliyetinin düşük
olması istenmektedir. Bunları sağlamak için nükleer reaksiyonların teorik
olarak önceden araştırılması gereklidir. Bu çalışmada, tiroid ve böbrek
kanserinin teşhis ve tedavisinde kullanılan 131I’ nın farklı üretim
yöntemleri araştırılmıştır.131I radyoizotopunun (p,f) reaksiyonları ile
üretilmesi için muhtemel reaksiyonlar teorik olarak incelenmiştir. Teorik
çalışmalar için TALYS bilgisayar kodu içerisinde yer alan fisyon bariyer
modelleri kullanılmıştır. Her bir model hem birbirleri ile hem de EXFOR veri tabanından
alınan deneysel veriler ile karşılaştırmalı analizleri yapılmıştır.
Keywords
References
- Büyükuslu, H., Kaplan, A., Tel, E., Yıldırım, G., Aydın, A., 2010, Production Cross Sections of Medical 110, 111In Radioisotopes, Kerntechnik 75 (3) 103-108.
- Capote, R., vd., 2009. RIPL – Reference Input Parameter Library for Calculation of Nuclear Reactions and Nuclear Data Evaluations. Nuclear Data Sheets 110. 3107–3214.
- Demir, B., Kaplan, A., Çapalı, V., Sarpün, İ. H., Aydın, A. and Tel, E., 2015, Production Cross–Section Calculations of Medical 32P, 117Sn, 153Sm and 186,188Re Radionuclides Used in Bone Pain Palliation Treatment, Kerntechnik 80 (1), 58-65.
- Gediklioğlu, A., 1988. Çekirdek Fiziğine Giriş. Karadeniz Teknik Üniversitesi Basımevi, Yayın No: 130, 220s. Trabzon.
- Gündoğdu E. A, Özgenç E., Ekinci M., Özdemir D., Aşıkoğlu M., 2018, Nükleer Tıpta Görüntüleme ve Tedavide Kullanılan Radyofarmasötikler, J. Lit. Pharm Sci., 7 (1) 24-34.
- Koning, A. J., Hilaire, S., Goriely S. 2018. “TALYS–1.9 A Nuclear Reaction Program, User Manual”, Nuclear Research and Consultancy Group (NRG), Netherlands.
- Krappe, H. J., Nix, J. R. Ve Sierk A.J., 1979. Unified Nuclear Potential For Heavy-İon Elastic Scattering, Fusion, Fission, and Ground-State Masses And Deformations. Phys. Rev. C20, 992.
- Mamdouh, A., Pearson, J.M., Raget, M. and Tondeur, F. 2001. Fission barriers of neutron–rich and superheavy nuclei calculated with the ETFSI method. Nuclear Physics A, 679: 337–358.
- NRDC-EXFOR (Experimental Nuclear Reaction Data File), Database Version of Mayıs 5, 2019. Brookhaven National Laboratory National Nuclear Data Centre. http://www.nndc.bnl.gov/nndc/exfor/. Son Erişim Tarihi: 05.04.2019.
- Tel, E., Aydın, A., Kara, A., Kaplan, A., 2012, Investigation of Ground State Features for Some Medical Radionuclides Using an effective Nuclear Force, Kerntechnik 77 (1) 50-55.
- World Healt Organization, Latest Global Cancer Data, The International Agency for Research on Cancer (IARC), France (September 12, 2018).
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Makaleler |
| Authors | |
| Publication Date | March 27, 2022 |
| Published in Issue | Year 2022 Volume: 15 Issue: 1 |
