Evaluation of Hematological Parameters in Differentiating Central and Peripheral Vertigo in Patients with Vertigo

Year 2023, Volume: 16 Issue: 3, 608 - 614, 31.12.2023

Orhan Tanrıverdi , Zeynep Çakır

https://doi.org/10.18185/erzifbed.1029791

Abstract

Abstract
Central and peripheral causes play a role in the etiology of patients who apply to the emergency department with the complaint of vertigo. In our study, in the differential diagnosis of patients with central and peripheral vertigo, the usability of hematological parameters (white blood cell (WBC), leukocyte, neutrophil, lymphocyte, monocytes, basophil, eosinophil and platelet counts, red cell distribution width (RDW), platelet distribution width (PDW)) and platelet/lymphocyte (PLR), neutrophil/lymphocyte (NLR) ratios was investigated. This is a retrospective study including 215 patients, 179 (83.3%)with peripheral vertigo and 36 (16.7%) with central vertigo. Patients who were discharged from the emergency department with the complaint of vertigo or were admitted to the otolaryngology clinic were considered as peripheral vertigo, and patients who had findings on central imaging or were hospitalized in neurology/neurosurgery clinics were considered as central vertigo. There was a statistically significant difference between the groups in terms of age and gender of patients with peripheral and central vertigo (p<0.05). There was no statistically significant difference between the groups in terms of hematological parameters (p>0.05). We found that the values we looked at were not useful in the differential diagnosis.

Öz
Acil servise vertigo şikayetiyle başvuran hastaların etiyolojisinde santral ve periferik sebepler rol oynamaktadır. Çalışmamızda santral ve periferik vertigolu hastaların ayırıcı tanısında hematolojik parametrelerin(beyaz küre, lökosit, nötrofil, lenfosit, monosit, bazofil, eozinofil ve trombosit sayıları, kırmızı küre dağılım genişliği (RDW), platelet dağılım genişliği (PDW)), ve platelet/lenfosit, nötrofil/lenfosit oranlarının kullanılabilirliği araştırıldı. Bu çalışma 179’u (%83.3) periferik vertigo, 36’sı (%16.7) santal vertigo olan toplam 215 hastanın dahil edildiği retrospektif bir çalışmadır. Acil servise vertigo şikayetiyle başvurup taburcu edilen ya da kulak burun boğaz kliniğine yatırılan hastalar periferik vertigo olarak, santral görüntülemelerde bulgusu olan ya da nöroloji/nöroşirurji kliniklerine yatırılan hastalar santral vertigo olarak kabul edildi. Periferik ve santral vertigolu hastaların yaş ve cinsiyet durumları bakımından gruplar arasında istatistiksel olarak anlamlı fark saptandı(p<0.05). Gruplar arasında hematolojik parametreler bakımından istatistiksel olarak anlamlı bir fark yoktu(p>0.05). Baktığımız değerlerin ayırıcı tanıda faydalı olmadığını saptadık.

Keywords

Central vertigo, peripheral vertigo, hematological parameters, NLR (neutrophil/lymphocyte ratio)

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