Research Article
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Year 2024, Volume: 17 Issue: 2, 364 - 376, 31.08.2024
https://doi.org/10.18185/erzifbed.1425404

Abstract

Project Number

AHİLAB.A4.23.002

References

  • [1] Adjissi, L., Chafai, N., Benbouguerra, K., Kirouani, I., Hellal, A., Layaida, H., ... & Chafaa, S. (2023). New aromatic hydrazones: Synthesis, structural analysis, DFT study, biological activity, ADME-T properties and in silico evaluation of their inhibition of SAS-CoV-2 main protease. Journal of Molecular Structure, 1279, 134997.
  • [2] Boora, A., Devi, J., Rom, T., & Paul, A. K. (2023). Synthesis, characterization, single crystal structure, biological evaluation of ONO donor hydrazones and their diorganotin (IV) complexes. Journal of Molecular Structure, 1284, 135386.
  • [3] Sinha, R., Singh, U. V. S., Khosa, R. L., & Jain, J. (2018). Anticonvulsant Activity of Isonicotinic Acid Hydrazone Derivatives Using MES, scPTZ and Rotorod Neurotoxicity Models. Journal of Applied Pharmaceutical Sciences and Research, 1(1):16-22.
  • [4] Sail, B. S., Naik, V. H., Prasanna, B. M., Ahmad, N., Khan, M. R., Jagadeesh, M. R., & Cheedarala, R. (2023). Synthesis, characterization and pharmacological studies of cobalt (II), nickel (II) and copper (II) complexes of thiazole schiff bases. Journal of Molecular Structure, 1288, 135748.
  • [5] Rohane, S. H., Redasani, V. K., Fuloria, N. K., & Fuloria, S. (2023). Synthesis, molecular docking and anti-inflammatory potential of novel hydrazones of eugenol in tuberculosis treatment. Indian Journal of Chemistry (IJC), 62(6), 551-558.
  • [6] Mohamed-Ezzat, R. A., Kariuki, B. M., & Elgemeie, G. H. (2023). Unexpected products of the reaction of cyanoacetylhydrazones of aryl/heteryl ketones with hydrazine: a new route to aryl/heteryl hydrazones, x-ray structure, and in vitro anti-proliferative activity against nci 60-cell line panel. Egyptian Journal of Chemistry, 66(13), 225-239.
  • [7] Kumar, R., Singh, A. A., Kumar, U., Jain, P., Sharma, A. K., Kant, C., & Faizi, M. S. H. (2023). Recent advances in synthesis of heterocyclic Schiff base transition metal complexes and their antimicrobial activities especially antibacterial and antifungal. Journal of Molecular Structure, 1294, 136346.
  • [8] Kiray, E. (2023). Cinnamomum verum Uçucu Yağının Pseudomonas aeruginosa ve Acinetobacter baumannii Üzerindeki Anti-biyofilm ve Anti-quarum Sensing Aktivitesi. Balıkesir Sağlık Bilimleri Dergisi, 12(1), 169-176.
  • [9] İnce, U. and Han, M.İ., (2023). Ufuk, İ. N. C. E., & Han, M. İ. (2023). Investigation of Antimicrobial Activity of Some Ethylparaben Hydrazide-Hydrazone Derivatives. Turkish Journal of Pharmaceutical Sciences, 20(1), 35.
  • [10] Kamboj, S., Thakral, S., Kumar, S., & Singh, V. (2023). Synthesis, Biological Evaluation and in Silico Studies of 3‐Hydroxy‐N‐(2‐(substituted phenyl)‐4‐oxothiazolidin‐3‐yl)‐2‐napthamide Derivatives. Chemistry & Biodiversity, 20(6), e202200976.
  • [11] Al-Hazmi, G. H. (2023). Synthesis, spectroscopic characterizations and cytotoxic activities of some novel 1, 2-bis-(tetrasubstituted-benzylidene) hydrazine analogues. Bulletin of the Chemical Society of Ethiopia, 37(6), 1503-1520.
  • [12] Despaigne, A. A. R., Da Silva, J. G., do Carmo, A. C. M., Piro, O. E., Castellano, E. E., & Beraldo, H. (2009). Structural studies on zinc (II) complexes with 2-benzoylpyridine-derived hydrazones. Inorganica Chimica Acta, 362(7), 2117-2122.
  • [13] Despaigne, A. A. R., Da Silva, J. G., Do Carmo, A. C. M., Piro, O. E., Castellano, E. E., & Beraldo, H. (2009). Copper (II) and zinc (II) complexes with 2-benzoylpyridine-methyl hydrazone. Journal of Molecular Structure, 920(1-3), 97-102.
  • [14] Meenatchi, V., Zo, S. M., Won, S. Y., Nam, J. W., Cheng, L., & Han, S. S. (2023). Cuminaldehyde-3-hydroxy-2-napthoichydrazone: Synthesis, effect of solvents, nonlinear optical activity, antioxidant activity, antimicrobial activity, and DFT analysis. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 302, 123071.
  • [15] Patil, S. A., Naik, V. H., Kulkarni, A. D., & Badami, P. S. (2010). DNA cleavage, antimicrobial, spectroscopic and fluorescence studies of Co (II), Ni (II) and Cu (II) complexes with SNO donor coumarin Schiff bases. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 75(1), 347-354.
  • [16] Baul, T. S. B., Nongsiej, K., Ka-Ot, A. L., Joshi, S. R., Rocha, B. G., & da Silva, M. F. C. G. (2020). Synthesis, crystal structures, magnetic properties and antimicrobial screening of octahedral nickel (II) complexes with substituted quinolin-8-olates and pyridine ligands. Journal of Molecular Structure, 1200, 127106.
  • [17] Maia, D. O., Santos, V. F., Barbosa, C. R., Fróes, Y. N., Muniz, D. F., Santos, A. L., ... & Teixeira, C. S. (2022). Nickel (II) chloride Schiff base complex: Synthesis, characterization, toxicity, antibacterial and leishmanicidal activity. Chemico-Biological Interactions, 351, 109714.
  • [18] Roy, T. G. (2020). Synthesis, characterization and antibacterial evaluation of some new nickel (II) complexes of a tetraazamacrocycle. Acta Scientific Pharmaceutical Sciences, 5, 60-69.

Synthesis, characterization and investigation of biological activities of Schiff base and its Ni(II) complex obtained from 2-Benzoylpyridine and 3-Hydroxy-2-naphthoic hydrazide

Year 2024, Volume: 17 Issue: 2, 364 - 376, 31.08.2024
https://doi.org/10.18185/erzifbed.1425404

Abstract

In this paper, a new aryl hydrazone and its Nickel (II) complex were synthesized from 2-benzoylpyridine and 3-Hydroxy-2-naphthoic hydrazide. The synthesized compounds were characterized by elemental analysis, UV Vis., IR, NMR spectral studies and mass spectra.
The data indicate that the metal atom is coordinated by the two ligands and that the [NiL2] complex is octahedral.
The ligand is coordinated through carbonyl-O, azomethine-N, and pyridyl-N atoms. When tested against various reference bacterial strains and clinical isolates, it was discovered that the antibacterial activity of the [NiL2] complex was more effective than the ligand.

Supporting Institution

Kırşehir Ahi Evran Üniversitesi

Project Number

AHİLAB.A4.23.002

References

  • [1] Adjissi, L., Chafai, N., Benbouguerra, K., Kirouani, I., Hellal, A., Layaida, H., ... & Chafaa, S. (2023). New aromatic hydrazones: Synthesis, structural analysis, DFT study, biological activity, ADME-T properties and in silico evaluation of their inhibition of SAS-CoV-2 main protease. Journal of Molecular Structure, 1279, 134997.
  • [2] Boora, A., Devi, J., Rom, T., & Paul, A. K. (2023). Synthesis, characterization, single crystal structure, biological evaluation of ONO donor hydrazones and their diorganotin (IV) complexes. Journal of Molecular Structure, 1284, 135386.
  • [3] Sinha, R., Singh, U. V. S., Khosa, R. L., & Jain, J. (2018). Anticonvulsant Activity of Isonicotinic Acid Hydrazone Derivatives Using MES, scPTZ and Rotorod Neurotoxicity Models. Journal of Applied Pharmaceutical Sciences and Research, 1(1):16-22.
  • [4] Sail, B. S., Naik, V. H., Prasanna, B. M., Ahmad, N., Khan, M. R., Jagadeesh, M. R., & Cheedarala, R. (2023). Synthesis, characterization and pharmacological studies of cobalt (II), nickel (II) and copper (II) complexes of thiazole schiff bases. Journal of Molecular Structure, 1288, 135748.
  • [5] Rohane, S. H., Redasani, V. K., Fuloria, N. K., & Fuloria, S. (2023). Synthesis, molecular docking and anti-inflammatory potential of novel hydrazones of eugenol in tuberculosis treatment. Indian Journal of Chemistry (IJC), 62(6), 551-558.
  • [6] Mohamed-Ezzat, R. A., Kariuki, B. M., & Elgemeie, G. H. (2023). Unexpected products of the reaction of cyanoacetylhydrazones of aryl/heteryl ketones with hydrazine: a new route to aryl/heteryl hydrazones, x-ray structure, and in vitro anti-proliferative activity against nci 60-cell line panel. Egyptian Journal of Chemistry, 66(13), 225-239.
  • [7] Kumar, R., Singh, A. A., Kumar, U., Jain, P., Sharma, A. K., Kant, C., & Faizi, M. S. H. (2023). Recent advances in synthesis of heterocyclic Schiff base transition metal complexes and their antimicrobial activities especially antibacterial and antifungal. Journal of Molecular Structure, 1294, 136346.
  • [8] Kiray, E. (2023). Cinnamomum verum Uçucu Yağının Pseudomonas aeruginosa ve Acinetobacter baumannii Üzerindeki Anti-biyofilm ve Anti-quarum Sensing Aktivitesi. Balıkesir Sağlık Bilimleri Dergisi, 12(1), 169-176.
  • [9] İnce, U. and Han, M.İ., (2023). Ufuk, İ. N. C. E., & Han, M. İ. (2023). Investigation of Antimicrobial Activity of Some Ethylparaben Hydrazide-Hydrazone Derivatives. Turkish Journal of Pharmaceutical Sciences, 20(1), 35.
  • [10] Kamboj, S., Thakral, S., Kumar, S., & Singh, V. (2023). Synthesis, Biological Evaluation and in Silico Studies of 3‐Hydroxy‐N‐(2‐(substituted phenyl)‐4‐oxothiazolidin‐3‐yl)‐2‐napthamide Derivatives. Chemistry & Biodiversity, 20(6), e202200976.
  • [11] Al-Hazmi, G. H. (2023). Synthesis, spectroscopic characterizations and cytotoxic activities of some novel 1, 2-bis-(tetrasubstituted-benzylidene) hydrazine analogues. Bulletin of the Chemical Society of Ethiopia, 37(6), 1503-1520.
  • [12] Despaigne, A. A. R., Da Silva, J. G., do Carmo, A. C. M., Piro, O. E., Castellano, E. E., & Beraldo, H. (2009). Structural studies on zinc (II) complexes with 2-benzoylpyridine-derived hydrazones. Inorganica Chimica Acta, 362(7), 2117-2122.
  • [13] Despaigne, A. A. R., Da Silva, J. G., Do Carmo, A. C. M., Piro, O. E., Castellano, E. E., & Beraldo, H. (2009). Copper (II) and zinc (II) complexes with 2-benzoylpyridine-methyl hydrazone. Journal of Molecular Structure, 920(1-3), 97-102.
  • [14] Meenatchi, V., Zo, S. M., Won, S. Y., Nam, J. W., Cheng, L., & Han, S. S. (2023). Cuminaldehyde-3-hydroxy-2-napthoichydrazone: Synthesis, effect of solvents, nonlinear optical activity, antioxidant activity, antimicrobial activity, and DFT analysis. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 302, 123071.
  • [15] Patil, S. A., Naik, V. H., Kulkarni, A. D., & Badami, P. S. (2010). DNA cleavage, antimicrobial, spectroscopic and fluorescence studies of Co (II), Ni (II) and Cu (II) complexes with SNO donor coumarin Schiff bases. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 75(1), 347-354.
  • [16] Baul, T. S. B., Nongsiej, K., Ka-Ot, A. L., Joshi, S. R., Rocha, B. G., & da Silva, M. F. C. G. (2020). Synthesis, crystal structures, magnetic properties and antimicrobial screening of octahedral nickel (II) complexes with substituted quinolin-8-olates and pyridine ligands. Journal of Molecular Structure, 1200, 127106.
  • [17] Maia, D. O., Santos, V. F., Barbosa, C. R., Fróes, Y. N., Muniz, D. F., Santos, A. L., ... & Teixeira, C. S. (2022). Nickel (II) chloride Schiff base complex: Synthesis, characterization, toxicity, antibacterial and leishmanicidal activity. Chemico-Biological Interactions, 351, 109714.
  • [18] Roy, T. G. (2020). Synthesis, characterization and antibacterial evaluation of some new nickel (II) complexes of a tetraazamacrocycle. Acta Scientific Pharmaceutical Sciences, 5, 60-69.
There are 18 citations in total.

Details

Primary Language English
Subjects Transition Metal Chemistry, Organometallic Chemistry
Journal Section Makaleler
Authors

Murat Çınarlı 0000-0003-3240-9508

Project Number AHİLAB.A4.23.002
Publication Date August 31, 2024
Submission Date January 25, 2024
Acceptance Date July 1, 2024
Published in Issue Year 2024 Volume: 17 Issue: 2

Cite

APA Çınarlı, M. (2024). Synthesis, characterization and investigation of biological activities of Schiff base and its Ni(II) complex obtained from 2-Benzoylpyridine and 3-Hydroxy-2-naphthoic hydrazide. Erzincan University Journal of Science and Technology, 17(2), 364-376. https://doi.org/10.18185/erzifbed.1425404