Vitamins A, E, and C: Mechanisms of Antioxidant Action and Physiological Impact

Year 2025, Volume: 34 Issue: 3, 536 - 545, 30.12.2025

Feride Koca , Elif Yılmaz , Leyla Çimen

https://doi.org/10.34108/eujhs.1727061

https://izlik.org/JA47BG64XD

Abstract

This study addresses the antioxidant effects of vitamins A, E, and C and their contributions to the maintenance of human health. Excessive production of free radicals can lead to oxidative stress, negatively affecting cellular components such as lipids, proteins, and DNA; this, in turn, contributes to the onset of various chronic diseases, including aging-related conditions, cancer, cardiovascular diseases, and neurodegenerative disorders. Antioxidants are vital for counteracting these harmful effects. Both endogenously produced and externally sourced antioxidants neutralize free radicals, reducing cellular damage and strengthening the body’s defense systems. The antioxidant properties of vitamins A, E, and C play a critical role in protecting cellular components from oxidative damage by mitigating the effects of oxidative stress. Adequate intake of these vitamins through a balanced diet enhances the body’s antioxidant capacity, providing protective effects against aging and the development of chronic diseases. This review aims to provide a better understanding of the physiological roles, antioxidant mechanisms, and overall impact of vitamins A, E, and C on human health.

Keywords

Antioxidant effects , antioxidant vitamins , vitamin A , vitamin C , vitamin E.

A, E ve C Vitaminleri: Antioksidan Etki Mekanizmaları ve Fizyolojik Etkileri

https://izlik.org/JA47BG64XD

Abstract

Bu çalışma A, E ve C vitaminlerinin antioksidan etkilerini ve insan sağlığının korunmasındaki katkılarını ele almaktadır. Serbest radikallerin aşırı üretimi, oksidatif strese yol açarak lipidler, proteinler ve DNA gibi hücresel bileşenleri olumsuz etkiler; bu durum yaşlanma, kanser, kardiyovasküler hastalıklar ve nörodejeneratif bozukluklar dahil olmak üzere birçok kronik hastalığın başlangıcına katkıda bulunur. Antioksidanlar, bu zararlı etkileri dengelemek açısından hayati öneme sahiptir. Hem vücut tarafından üretilen hem de dış kaynaklı alınan antioksidanlar, serbest radikalleri etkisiz hale getirerek hücresel hasarı azaltır ve vücudun savunma sistemlerini güçlendirir. A, E ve C vitaminlerinin antioksidan özellikleri, oksidatif stresin etkilerini azaltarak hücresel bileşenleri oksidatif hasardan korumada kritik bir rol oynar. Dengeli bir beslenme ile bu vitaminlerin yeterli düzeyde alınması vücudun antioksidan kapasitesini artırarak yaşlanma sürecine ve kronik hastalıkların gelişimine karşı koruyucu etkiler sağlar. Bu derleme A, E ve C vitaminlerinin fizyolojik rollerini, antioksidan mekanizmalarını ve insan sağlığı üzerindeki genel etkilerini daha iyi anlamayı amaçlamaktadır.

Keywords

Antioksidan etkiler , antioksidan vitaminler , A vitamini , C vitamini , E vitamini.

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