IS THERE A RELATION BETWEEN ZINC LEVELS, AND RECURRENT RESPIRATORY SYSTEM I NFECTIONS IN CHILDREN?

Year 2018, Volume: 27 Issue: 1, 36 - 39, 01.03.2018

Özlem Naciye Şahin Nuray Keçecioğlu Muhittin Serdar Aysel Özpınar

Abstract

Amaç: Eser elementlerin ve D vitaminin eksik alımı ve
allerji çocuk solunum sistemi sağlığı üzerine etkileri bulunmaktadır. Kesitsel çalışmamızda tekrar eden solunum yolun yolu enfeksiyonu ile çinko düzeyleri ve neden olabilecek diğer faktörlerin ilişkisini araştırmak amaçlanmaktadır.
Metod: 2015-2017 tekrar eden akut otitis media, farenjit,
rinit gibi üst solunum yolu enfeksiyonu ve alt solunum yolu
enfeksiyonu olan, Türkiye’de yaşayan 249 olgu ve 122
sağlıklı kontrol çalışmaya dahil edilmiştir. Çinko düzeyleri,
adenoid hipertrofi varlığı allerji deri testi, yaş, cinsiyet,
tekrar eden alt veya üst solunum yolu enfeksiyonu öyküsü
değerlendirilmiştir.
Sonuçlar: 180 kız, 191 erkek olmak üzere 371 olgu
(ortalama ± SD, 47±31 ay), çalışmaya dahil edilmiştir. Tekrar eden üst ve alt solunum yolu enfeksiyonu ile çinko düzeyleri (ortalama ± SD, 0,88±0,28), (ortalama ± SD,
0,88±0,35), arasında anlamlı ilişki saptanmamıştır. Tekrar
eden solunum yolu enfeksiyonu olan olgular ile sağlıklı
grup arasında, IgE düzeyleri açısından anlamlı istatistiksel
fark bulunmamıştır (p=0,4). D vitamini düzeyleri tekrar
eden alt ve üst solunum yolu enfeksiyonu olan grupta anlamlı olarak düşük bulunmuştur(p=0,001).
Sonuç: Sağlıklı kontroller ile tekrar eden solunum yolu
enfeksiyonu olan olgular arasında çinko düzeyleri açısından anlamlı fark saptanmamıştır. Tekrar eden solunum
yolu enfeksiyonunda çinko suplementasyonu ancak eksikliği saptanmış olgulara önerilebilir, ve bu olgular tekrar
eden solunum yolu enfeksiyonunda bağımsız risk faktörü
olan adenoid hipertrofi varlığı açısından değerlendirilmelidir.

Keywords

Çinko, solunum, çocuk

Çocuklarda Çinko Düzeyleri İle Tekrar Eden Solunum Yolu Enfeksiyonu Arasında İlişki Var Mıdır?

Abstract

Objective: There are many consequences connected with an
inadequate intake of trace elements and Vitamin D. Allergic
disorders and a susceptibility to respiratory infections may
be related to deficiencies of trace elements and/or vitamin
D. This cross-sectional study aims to investigate associations between recurrent respiratory system infections and
Zinc levels; as well as other dependent factors.
Methods: Three hundred and seventy one children living in
Turkey were enrolled in the study between 2015 and 2017.
Two hundred and forty nine had a history of either recurrent upper respiratory infections such as, acute otitis media, pharyngitis, rhinitis, or lower respiratory tract infections. 122 were considered as healthy controls. Age, gender, existence of adenoid hypertrophy, upper and lower
respiratory tract infections, zinc levels, vitamin D levels, IgE
levels, and a skin prick test were all evaluated.
Results: A total of 371 children (mean age ± standard deviation = 47±31 months), 180 males and 191 females were
included. No significant difference between the zinc levels
of children with recurrent upper (mean ± standard deviation = 0,88±0,28) respiratory tract infections and lower
respiratory tract (mean ±standard deviation= 0,88±0,35)
infections was observed. Likewise, there was no significant
difference between IgE levels of children with recurrent
respiratory tract infections and healthy controls (p=0,4).
Vitamin D levels, however, were found to be significantly
lower in children with lower and upper respiratory tract
infections (p=0,001).
Conclusion: There was no significant difference in zinc levels between healthy controls and children with recurrent
respiratory tract infections. However, if there is a documented low zinc deficiency, children with recurrent respiratory tract infections may be recommended a zinc supplementation protocol. Additionally, these children should also
be monitored for adenoid hypertrophy; an independent
risk factor for recurrent respiratory tract infections.

Keywords

Zinc, Respiratory, Child

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