DISTRIBUTION OF ORAL PATHOLOGIES: A RETROSPECTIVE ANALYSIS IN KAYSERI REGION.

Year 2019, Volume: 28 Issue: 2, 70 - 74, 20.09.2019

Emrah Soylu , Kübra Öztürk , Osman Etöz Cihan Topan Alper Alkan

https://doi.org/10.34108/eujhs.452179

Abstract

Pathology is an
important discipline which can make the definitive diagnose of the lesions and
helps surgeon for the treatment of the lesions. Biopsy materials which were
taken from the oral maxillofacial area examined by pathologist and the results
helps the surgeon to identfy the characteristic of the lesion and possible
treatment modalities of the lesions. This study includes the biopsy results
which were taken from the patients who refered to ERU Dentistry Faculty department
of Oral Maxillofacial Surgery between the years of 2005-2011. 479 biopsy
results were included in this study. As the result of this study 96.9% (n=464)
biopsy were benign lesions, 3.1% (n=15) were malign lesions, 25.2% (n=121) were
infection cyst, 13.3% (n=64) were developmental cyst, 3.5% (n=17) were
non-odontogenic cyst, 5.4% (n=26) were benign odontogenic tumor, 8.7% (n=42)
were benign non-odontogenic tumor, 37.1% (n=178) were benign re-active lesions,
3.3% (n=16) were benign fibro-osseous lesion. In our country, patients who are
complaining about the lesion in oral cavity, refered to department of plastic
and reconstrucitve surgery and department of otolaryngology clinics instead of
oral and maxillofacial department. This can be the possible reason for the low
rate result of malign lesion in this study.

Keywords

Pathology, Oral Pathology, Biopsy, Maxillofacial Biopsy

ORAL PATOLOJİLERİN DAĞILIMI: KAYSERİ BÖLGESİNDE RETROSPEKTİF ANALİZİ.

Abstract

Patoloji
lezyonların kesin tanısını koyabilen ve lezyonların tedavisi için cerrahlara
yardımcı önemli bir disiplindir. Oral ve maksillofasiyal alandan alınan biyopsi
materyalleri patolog tarafından incelenerek, cerrahlara lezyonun karakteristiği
ve olası tedavi şekillerinin tanımlanmasına yardımcı olur. Bu çalışma,
2005-2011 yılları arasında ERU Diş Hekimliği Ağız Diş Çene Cerrahisi Kliniğine
başvuran hastalardan alınan biyopsi sonuçlarını içermektedir. Çalışma 479
biyopsi sonuçlarını değerlendirmektedir. Bu çalışmanın sonuçları %96.9(n=464)
iyi huylu lezyon, %3.1(n=15) malign lezyon,%25.2(n=121) biyopsi iyi huylu
lezyon,% 3.1 (n = 15) malign lezyon,% 25.2 (n = 121) inflamatuar kist, % 13.3
(n = 64) gelişimsel kist,% 3.5 (n = 17) non-odontojenik kist, % 5.4 (n = 26)
benign odontojenik tümör,% 8.7 (n = 42) benign non-odontojenik tümör,% 37.1 (n
= 178) benign reaktif lezyonlar,% 3.3 (n = 16) benign fibro-osseöz lezyon
göstermektedir. Ülkemizde, oral kavitede lezyondan şikayeti olan hastalar, oral
ve maksillofasiyal bölüm yerine plastik ve rekonstrüktif cerrahi ve kulak burun
boğaz kliniği bölümlerine başvurmaktadır. Bu çalışmada düşük malign lezyon
sonucunun olası nedeninin bu durumun olabileceği düşünülmektedir.

Keywords

Patoloji, Oral Patoloji, Biyopsi, Maksillofasiyal Biyopsi

References

• REFRENCE1. Mota-Ramírez A, Silvestre FJ, Simó JM. Oral biopsy in dental practice. Medicina Oral, Patología Oral y Cirugía Bucal (Internet). 2007;12:504-10.
• REFRENCE2. Karkera BV, Shivakumar B, Mohammed A, Vidya M, Hemanth M. Biopsy: Clinical implications. Journal of Dentistry and Oral Hygiene. 2011;3:106-8.
• REFRENCE3. Khoo SP. Oral biopsy in dental practice-the Pathologist's perspective. Ann Dent. 1995;2:29-32.
• REFRENCE4. Alanazı YM, Alrwuılı MR, Latıf K, Alenzı NA, Alenzı BA, Aljabab MA. A 5-years retrospectıve study of oral pathologıcal lesıons ın 425 Saudı patıents. Pakistan Oral & Dental Journal. 2016;36.
• REFRENCE5. Sharma Gagan K, Manish S. Oral Biopsy—Revisited! Annals of Dental Research. 2011;vol1:44-53.
• REFRENCE6. Logan R, Goss A. Biopsy of the oral mucosa and use of histopathology services. Aust Dent J. 2010;55:9-13.
• REFRENCE7. Hohlweg-Majert B, Deppe H, Metzger MC, Schumm S, Hoefler H, Kesting MR, et al. Sensitivity and specificity of oral brush biopsy. Cancer Invest. 2009;27:293-7.
• REFRENCE8. Sylvie-Louise Avon D, Klieb HB. Oral soft-tissue biopsy: an overview. J Can Dent Assoc. 2012;78:c75.
• REFRENCE9. Zuber TJ. Punch biopsy of the skin. Am Fam Physician. 2002;65:1155-8, 61-2, 64.
• REFRENCE10. Oliver R, Sloan P, Pemberton M. Verifiable CPD paper: Oral biopsies: methods and applications. Br Dent J. 2004;196:329-33.
• REFRENCE11. Melrose RJ, Handlers JP, Kerpel S, Summerlin D, Tomich CJ. The use of biopsy in dental practice: the position of the American Academy of Oral and Maxillofacial Pathology. General dentistry. 2007;55:457.
• REFRENCE12. Chen S, Forman M, Sadow PM, August M. The Diagnostic Accuracy of Incisional Biopsy in the Oral Cavity. J Oral Maxillofac Surg. 2016;74:959-64.
• REFRENCE13. Lousada-Fernandez F, Rapado-Gonzalez O, Lopez-Cedrun J, Lopez-Lopez R, Muinelo-Romay L, Suarez-Cunqueiro M. Liquid Biopsy in Oral Cancer. International journal of molecular sciences. 2018;19.
• REFRENCE14. Hupp JR, Ellis E, Tucker MR. Contemporary Oral and Maxillofacial Surgery. Fifth ed: Mosby Elsevier; 2008.
• REFRENCE15. Fragiskos FD. Oral surgery: Springer Science & Business Media; 2007.
• REFRENCE16. Camacho-Alonso F, Lopez-Jornet P. Study of pain and swelling after oral mucosal biopsy. Br J Oral Maxillofac Surg . 2008;46:301-3.
• REFRENCE17. Rohilla M, Namdev R, Dutta S. Dentigerous cyst containing multiple impacted teeth: A rare case report. Journal of Indian Society of Pedodontics and Preventive Dentistry. 2011;29:244.
• REFRENCE18. Theodorou DJ, Theodorou SJ, Sartoris DJ. Primary non-odontogenic tumors of the jawbones: an overview of essential radiographic findings. Clin Imaging. 2003;27:59-70.
• REFRENCE19. Vedtofte P, Praetorius F. The inflammatory paradental cyst. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1989;68:182-8.
• REFRENCE20. Özkan A, Okçu KM, Şençimen M, Bayar GR, Gülses A, Günhan Ö. Nonsendromik bilateral mandibular dentigeröz kist: olgu sunumu. Gulhane Medical Journal. 2011;53.
• REFRENCE21. Avelar RL, Antunes AA, Carvalho RW, Bezerra PG, Oliveira Neto PJ, Andrade ES. Odontogenic cysts: a clinicopathological study of 507 cases. Journal of oral science. 2009;51:581-6.
• REFRENCE22. Nunez-Urrutia S, Figueiredo R, Gay-Escoda C. Retrospective clinicopathological study of 418 odontogenic cysts. Med Oral Patol Oral Cir Bucal. 2010;15:e767-73.
• REFRENCE23. Ledesma-Montes C, Hernández-Guerrero JC, Garcés-Ortı́z M. Clinico-pathologic study of odontogenic cysts in a Mexican sample population. Arch Med Res. 2000;31:373-6.
• REFRENCE24. Mosqueda-Taylor A, Irigoyen-Camacho M, Diaz-Franco M, Torres-Tejero M. Odontogenic cysts. Analysis of 856 cases. Medicina oral: organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal. 2001;7:89-96.
• REFRENCE25. Ochsenius G, Escobar E, Godoy L, Peñafiel C. Odontogenic cysts: analysis of 2.944 cases in Chile. Med Oral Patol Oral Cir Bucal. 2007;12:85-91.
• REFRENCE26. Shah SK, Le MC, Carpenter WM. Retrospective review of pediatric oral lesions from a dental school biopsy service. Pediatr Dent. 2009;31:14-9.
• REFRENCE27. Peker E, Öğütlü F, Karaca İR, Gültekin ES, Çakır M. A 5 year retrospective study of biopsied jaw lesions with the assessment of concordance between clinical and histopathological diagnoses. Journal of oral and maxillofacial pathology: JOMFP. 2016;20:78.
• REFRENCE28. Simon EN, Merkx MA, Vuhahula E, Ngassapa D, Stoelinga PJ. A 4-year prospective study on epidemiology and clinicopathological presentation of odontogenic tumors in Tanzania. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:598-602.
• REFRENCE29. Ladeinde AL, Ajayi OF, Ogunlewe MO, Adeyemo WL, Arotiba GT, Bamgbose BO, et al. Odontogenic tumors: a review of 319 cases in a Nigerian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:191-5.
• REFRENCE30. Wright JM, Odell EW, Speight PM, Takata T. Odontogenic tumors, WHO 2005: where do we go from here? Head and neck pathology. 2014;8:373-82.
• REFRENCE31. Soluk-Tekkeşin M, Wright JM. The world health organization classification of odontogenic lesions: a summary of the changes of the 2017 (4th) edition. Turkish Journal of Pathology. 2018;34.
• REFRENCE32. Johnson NR, Gannon OM, Savage NW, Batstone MD. Frequency of odontogenic cysts and tumors: a systematic review. Journal of investigative and clinical dentistry. 2014;5:9-14.
• REFRENCE33. Ağır H, Şen C, Işıl E, Ünal Ç, Üstündağ E, Keskin G. Çenenin odontojenik ve odontojenik olmayan kistleri: 25 olguda deneyimlerimiz. Kulak Burun Bogaz Ihtis Derg. 2008;18:157-65.
• REFRENCE34. Gotmare SS, Tamgadge A, Pereira T, Shetty A. Keratocystic odontogenic tumor with ossification and calcification: A case report with unusual histological findings. Indian Journal of Dental Research. 2016;27:441.
• REFRENCE35. El-Gehani R, Orafi M, Elarbi M, Subhashraj K. Benign tumours of orofacial region at Benghazi, Libya: a study of 405 cases. J Craniomaxillofac Surg. 2009;37:370-5.
• REFRENCE36. Fernandes AM, Duarte ECB, Pimenta FJGS, Souza LN, Santos VR, Mesquita RA, et al. Odontogenic tumors: a study of 340 cases in a Brazilian population. J Oral Pathol Med. 2005;34:583-7.
• REFRENCE37. Regezi JA. Odontogenic cysts, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws. Mod Pathol. 2002;15:331-41.
• REFRENCE38. Kashyap B, Reddy PS, Nalini P. Reactive lesions of oral cavity: A survey of 100 cases in Eluru, West Godavari district. Contemporary clinical dentistry. 2012;3:294.
• REFRENCE39. Jalayer Naderi N, Eshghyar N, Esfehanian H. Reactive lesions of the oral cavity: A retrospective study on 2068 cases. Dental research journal. 2012;9.
• REFRENCE40. Llewellyn C, Johnson NW, Warnakulasuriya K. Risk factors for squamous cell carcinoma of the oral cavity in young people—a comprehensive literature review. Oral Oncol. 2001;37:401-18.