Toxoplasma gondii seropositivity in pregnancies with normal delivery and complicated with abortion

Year 2018, , 275 - 279, 04.10.2018

Burcu Dinçgez Çakmak , Betül Dündar , Feyza Bayram Gülten Özgen

https://doi.org/10.18621/eurj.339882

Cited By: 6

Abstract

Objective: Toxoplasma infection during pregnancy may cause remarkable
mortality and morbidityin fetus due to transplacental transmission. It has
fetal consequences such as abortion, stillbirth and congenital malformations.
In the Turkish literature, there is limited investigations evaluating the
prevalence of Toxoplasma gondii among
pregnancies complicated with abortion. The aim of this study is to compare the Toxoplasma seropositivity between
pregnancies with normal delivery and complicated with abortion. 

Methods:
This is a retrospective, single center study conducted between May 2015 and
June 2016. We included 412 patients in the study group and 828 patients in the
control group. The study group (Group 1) was compromised of pregnants whose
pregnancies were complicated with abortion and the control group (Group 2) was
pregnants with normal delivery. Toxoplasma
IgM and IgG seropositivity were compared between two groups.

Results:
There was no difference between two groups in terms of sociodemographic
features (p > 0.05). Toxoplasma IgM was positive in 62 (5%)
patients and IgG was positive in 282 (22.9%) patients in all groups. In
subgroup analysis Toxoplasma IgM was
found to be positive in 27 (6.6%) patients in Group 1 and 35 (4.2%) patients in
Group 2. Moreover, Toxoplasma IgG was
positive in 125 (30.6%) patients in Group 1 and in 157 (19.2%) patients in
Group 2. Toxoplasma IgM and Toxoplasma IgG were significantly higher
in Group 1 (p = 0.023 and p = 0.016, respectively). 

Conclusion:
We concluded that Toxoplasma
seropositivity is high in our country and routine screening is essential for
pregnancies. Toxoplasmosis may play a role in the etiology of abortion. 

Keywords

Abortus, pregnancy, toxoplasmosis, toxoplasma immunglobuline

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