Zoonotik ajan: Rodentlerde Bartonella spp

Öz

Zoonotik ajanların konakçı türlerini belirlemek, ortaya çıkan bulaşıcı hastalıkları kontrol etmenin anahtarlarından biridir. Dünya çapında yapılan çalışmalar, kemirgenlerin bakteriyel ve viral bulaşıcı ajanların eko-epidemiyolojisinde önemli rol oynadığı göstermiştir. Aynı zamanda, kemirgenler, zoonoz etkenlerden olan Bartonella spp etkeninin doğal rezervuarlarıdır. Özellikle, konakçı ve rezervuar görevi üstlenen rodentlerlerde, Bartonella spp gibi göz ardı edilebilen patojenlerin izlenmesi ve epidemiyolojik çalışmalar yapılması önemlidir. Potansiyel halk sağlığı riskli bir etken olmasına ragmen, Bartonella spp etkeninin tespiti üzerine ülkemizde sınırlı sayıda araştırma yapılmıştır. Çalışmamızda, Türkiye’nin beş farklı yerleşim biriminden toplanan 41 rodent örneğinde real time PCR yöntemi ile Bartonella spp. varlığı araştırıldı. Real time PCR ile çalışılan rodent dalak örneklerinden 6’sı (% 14.63) Bartonella spp. yönünden pozitif bulundu. Çalışmamızın sonucunda, yabani kemirgen türlerinin, hastalığın oluşumunda olası rezervuar olarak kabul edilebileceği ve bu alanda daha fazla çalışmaya ihtiyaç olduğu kanaatine varıldı.

Anahtar Kelimeler

• Bartonella spp
• real time PCR
• rodent

Zoonotic agent: Bartonella spp in Rodents

Öz

Identifying the host types of zoonotic agents is one of the keys to controlling emerging infectious diseases. Worldwide studies have shown that rodents play an important role in the eco-epidemiology of bacterial and viral infectious agents. At the same time, rodents are natural reservoirs of Bartonella spp. It is important to monitor negligible pathogens such as Bartonella spp. especially in rodents that act as hosts and reservoirs, and to conduct epidemiological studies. Although it is a potential public health risk factor, a limited number of studies have been conducted in our country on the detection of Bartonella spp. In our study, existence of Bartonella spp. was investigated by real time PCR method 41 rodent samples collected from five different settlements in Turkey. A total number of six rodent spleen samples studied with real time PCR were found positive for Bartonella spp. (14.63%). As a result of our study, it was concluded that wild rodent species can be considered as possible reservoirs in the formation of the disease and further studies are needed in this area.

Anahtar Kelimeler

• Bartonella spp
• Real time PCR
• rodent

Kaynakça

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