Melatonin, Etkileri ve Kullanım Alanları

Yıl 2017, Cilt: 28 Sayı: 1, 7 - 12, 15.06.2017

Ayris Salt Metin Çenesiz , Sena Çenesiz

https://doi.org/10.35864/evmd.530085

Cited By: 2

Öz

 Melatonin günlük ve mevsimsel değişiklik gösterebilen pineal bezden salgılanan ve suprakiazmatik nukleus tarafından endojen ritmi düzenleyen bir hormondur. Günümüzde tıp ve veteriner hekimlikte ekzojen kullanım alanlarının genişlemesi bu hormonun önemini arttırmıştır. Hücresel kompartmanlara kolayca geçebilen bu hormon güçlü bir antioksidan özellik göstermekle beraber, sirkadyen ritmi düzenleyerek vücutta homeostazisi sağlar. Bağışıklık sistemi üzerine de olumlu etkileri bulunmaktadır. Bazı hayvan türlerinde de üreme siklusunu başlatıcı ya da inhibe edici etki gösterir. Yapılan çalışmalarla melatoninin antikanserojenik etkinliği ortaya koyulmuştur. Bu derlemede melatoninin biyokimyasal özellikleri ile kullanım alanları anlatılmaktadır.

Anahtar Kelimeler

Antikanserojenik etki, Antioksidan etki, Melatonin

Kaynakça

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