Ruminantlarda Mycobacterium avium subspecies paratuberculosis Enfeksiyonunun İmmunolojik Özellikleri

Yıl 2017, Cilt: 28 Sayı: 2, 109 - 114, 15.12.2017

Ezgi Şababoğlu , Hülya Türütoğlu

https://doi.org/10.35864/evmd.523468

Cited By: 1

Öz

Mycobacterium avium subspecies paratuberculosis, hayvan sağlığını etkileyen ve ciddi ekonomik kayıplara sebep olan önemli bir patojendir. Etkenin mevcut immun sistemden kaçma stratejileri nedeniyle bugüne kadar paratüberküloza karşı etkili bir aşı geliştirilememiş ve uygun bir koruma ve kontrol stratejisi belirlenememiştir. M. avium subsp. paratuberculosis’e karşı doğru kontrol stratejilerinin geliştirilebilmesi için konakçı-patojen etkileşimini düzenleyen hücresel ve moleküler mekanizmalar ile hastalığın patolojik temelinin detaylı olarak anlaşılması gerekmektedir. Bu derlemede; M. avium subsp. paratuberculosis ile konakçı ilişkisi ve konakçıda gelişen immunolojik reaksiyonlar üzerine kapsamlı bilgiler sunuldu.

Anahtar Kelimeler

İmmünoloji, konakçı savunması, Mycobacterium avium subspecies paratuberculosis

Kaynakça

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