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lmmunomodulators and their practıcol uses

Year 1990, Volume: 6 Issue: 6, 147 - 172, 01.12.1990

Osman Erganiş Osman Kaya

Abstract

Immunomodulators and their usage in Veterinary Medicine
Immunomodulater drugs which have been extesively using for the treatment of cancer and autoimmun diseases, and in tissue transplantation in human beings become more and more popular in Veterinary field in order to nonspesific stimulation of immun systems.
Nonspesific stimulation of humoral and cellular immunity by means of physiologic, sentetic and microbial immunomodulators have been suggested to decrase the incidance of infectious diseases.
Immunomodulator drugs having anti-tumoral and immunsupressive effects have been just started to use in the treatment of autoimmun diseases and cancer of pet animals.

References

  • ARDA,M., AKAY, Ö., AYDIN, N. ve iZGÜR. M. (1983) Tavuk tifosuna karşı etkin bir aşı hazırlanması üzerinde araştırmalar. A.Ü. Vet: Fak ... Derg. · 30 (3): 420-429
  • BLALOCK, J.E. and SMITH, E. M . (1985) : A complete regulatory loop between the immune and nouroendocrine systems. Fod. Procee. 4.4: 103-11_
  • COFFEY, R:G. and HADDEN, J.W. (1985) : Neurotransmitters, hormones and cyclic ·nucleotides in lymphocyte regulation. Fed. Procee. 44: 112~117.
  • CONFER. A.W. and ALDINGER, W.K (1981) : The in vivo effect of levamisole on PHA stimulation in normal and · Marek's Disease vinıs inoculated chickenq. Hes. Vet. Sc i. 30: 243-245
  • DiLŞEN. N . . (1984) : immunoregulatuvar Tedavi. Düzenleyen :· N. Dilşen, Temel ve Klinik immunoloji. i.ü. Tıp Fak. Re k. No. 274•6. Fak. No. 127. Sanal Matbaacılık. istanbul, · sh. 394-417
  • FLESH, J. HARIEL, W. and NELKEN, D. (1982) : ımmunpotentiating effect of levamisole in the prevention of bovine· mastitis, foetal death .and endometritis.Vet. Res. 111 (13) : 56,57 .
  • ISHIKAWA, H. · and .SHIMIZU, T. (1S83) <Depression . of B.lenphocytes by rnostitis and treatment •with levanıisole. J. üairy. Sci., 66: 556-561 .
  • JECKSTAD, S., LEIBOLJD, W., SCHRÖDER, J. and PETZOLDT. (1988) : lnvivo und in vitro Wirkungen eines blologischen ·. immunomodülators. ·. Berl. Müch ., Tier . Wschr. 1:01: 85-91.
  • KAUFMAN, S.H .E. (1987) : Lympphokine, in terleukine, Zytokine: Funktion und Wirkmechanismus. lmmun. lnfect. 15: 127-133. ·
  • MOLLI, M . (1986) : Prostoglandinler ve Kanser. Doğa; Tr: Tıp ve ECZ'. Der. 10(2): 173-186.
  • MORI, H., MiHARA, M., TESHIMA. K., UESAGI, V., YU, O., SAKAMATO, O. and KODA. A. (1987) : Effect of immunostimulants ·and ·Antitumor Agents on Tumor Necrosis Factor (TNF) production. Int. J. ımmunophamac . 9(8): ·884-892.
  • MOREIN, B. (1987) : lscom:an immunostimulating complex Arzneim-forsch/ Drug. Res: 37('12): 1418.
  • MULCAH·v. ·G. and . OUINN, P.J. (1986)': A review of immunonıodülatörs and iheir application in Veterinary ·Medicine. J ... Vet. Pharmacol. Therap. 9: 119-139.
  • SEAMEN, W.E. (1987) : lmmnoınodulation in: Basic and Clinical lmnıunology 6th. ed., edited by Stites. D.P .. Staıbo, J.D. and Wells-J.V. Appleteen and Lange, California., p. 228-237.
  • SWİTALA, M., HEBEL, T., WERNIEKI. A., DZIMIRA, R. and STRADAL, P. 1988) : Profylactic effects of Nitrogranulcgen (Chlormethine) given to preg- nant cows before parturition: Comparison· with levamisole. Medycyna Weterynaryina.44: 239-241.
  • VAJAYKUMER, D.S., RAMKRISHA, O. and HARAGOPEL, U. (1983) : Corynebacterium parvum induced regression of horn cancer in a bullock. Vet. Med. Smal Anim. Cli. 78: 1905-1908.
  • WINTERS, W.D., and HARRIS, S.C. (1982) : lnterferon induction in healthy and tumour bearing dogs by cell wallsof ·M.bovis, strain BCG. Am. J. Vet.Res: 43: 1232-1235.
  • YÜCEL, R. (1977) : Veteriner Şirurjide Transplantasyonlar. Fırat Üniver. Vet. · Fak. Der. 4: 80,96. :

İmmunomodülatörler ve Kullanım Alanları

Year 1990, Volume: 6 Issue: 6, 147 - 172, 01.12.1990

Osman Erganiş Osman Kaya

Abstract

İnsanlarda kanser tedavisinde, organ transplantasyonlarında ve otoimmun hastalıkların tedavisinde yoğun kullanım alanı bulan immunomodulatör ilaçlar/maddeler, Veteriner Hekimliğinde hayvanların immun sistemlerinin non-spesifik uyarılmaları amacıyla önem kazanmaktadır. Fizyolojik, Sentetik ve Mikrobiyel İmmunomedulatörlerin humoral ve sellular bağışıklığı , non-sepesifik olarak güçlendirmeleri, özellikle enfeksiyon hastalıklarının insidensinin, azaltılması için önerilmektedir. Anti-tümor etkili ummunomodülatör ilaçlar ile immunosupresif etkli immunmodulatür maddeler ev hayvanlarının kanserinde ve otoimmun hastalıkların tedavisinde kullanılmaktadır.

Keywords

İmmunomodülatörler İmmunomodülatörler Kullanım Alanları Osman ERGANİŞ Osman KAYA 1990 Etlik Veteriner Mikrobiyoloji Dergisi

References

  • ARDA,M., AKAY, Ö., AYDIN, N. ve iZGÜR. M. (1983) Tavuk tifosuna karşı etkin bir aşı hazırlanması üzerinde araştırmalar. A.Ü. Vet: Fak ... Derg. · 30 (3): 420-429
  • BLALOCK, J.E. and SMITH, E. M . (1985) : A complete regulatory loop between the immune and nouroendocrine systems. Fod. Procee. 4.4: 103-11_
  • COFFEY, R:G. and HADDEN, J.W. (1985) : Neurotransmitters, hormones and cyclic ·nucleotides in lymphocyte regulation. Fed. Procee. 44: 112~117.
  • CONFER. A.W. and ALDINGER, W.K (1981) : The in vivo effect of levamisole on PHA stimulation in normal and · Marek's Disease vinıs inoculated chickenq. Hes. Vet. Sc i. 30: 243-245
  • DiLŞEN. N . . (1984) : immunoregulatuvar Tedavi. Düzenleyen :· N. Dilşen, Temel ve Klinik immunoloji. i.ü. Tıp Fak. Re k. No. 274•6. Fak. No. 127. Sanal Matbaacılık. istanbul, · sh. 394-417
  • FLESH, J. HARIEL, W. and NELKEN, D. (1982) : ımmunpotentiating effect of levamisole in the prevention of bovine· mastitis, foetal death .and endometritis.Vet. Res. 111 (13) : 56,57 .
  • ISHIKAWA, H. · and .SHIMIZU, T. (1S83) <Depression . of B.lenphocytes by rnostitis and treatment •with levanıisole. J. üairy. Sci., 66: 556-561 .
  • JECKSTAD, S., LEIBOLJD, W., SCHRÖDER, J. and PETZOLDT. (1988) : lnvivo und in vitro Wirkungen eines blologischen ·. immunomodülators. ·. Berl. Müch ., Tier . Wschr. 1:01: 85-91.
  • KAUFMAN, S.H .E. (1987) : Lympphokine, in terleukine, Zytokine: Funktion und Wirkmechanismus. lmmun. lnfect. 15: 127-133. ·
  • MOLLI, M . (1986) : Prostoglandinler ve Kanser. Doğa; Tr: Tıp ve ECZ'. Der. 10(2): 173-186.
  • MORI, H., MiHARA, M., TESHIMA. K., UESAGI, V., YU, O., SAKAMATO, O. and KODA. A. (1987) : Effect of immunostimulants ·and ·Antitumor Agents on Tumor Necrosis Factor (TNF) production. Int. J. ımmunophamac . 9(8): ·884-892.
  • MOREIN, B. (1987) : lscom:an immunostimulating complex Arzneim-forsch/ Drug. Res: 37('12): 1418.
  • MULCAH·v. ·G. and . OUINN, P.J. (1986)': A review of immunonıodülatörs and iheir application in Veterinary ·Medicine. J ... Vet. Pharmacol. Therap. 9: 119-139.
  • SEAMEN, W.E. (1987) : lmmnoınodulation in: Basic and Clinical lmnıunology 6th. ed., edited by Stites. D.P .. Staıbo, J.D. and Wells-J.V. Appleteen and Lange, California., p. 228-237.
  • SWİTALA, M., HEBEL, T., WERNIEKI. A., DZIMIRA, R. and STRADAL, P. 1988) : Profylactic effects of Nitrogranulcgen (Chlormethine) given to preg- nant cows before parturition: Comparison· with levamisole. Medycyna Weterynaryina.44: 239-241.
  • VAJAYKUMER, D.S., RAMKRISHA, O. and HARAGOPEL, U. (1983) : Corynebacterium parvum induced regression of horn cancer in a bullock. Vet. Med. Smal Anim. Cli. 78: 1905-1908.
  • WINTERS, W.D., and HARRIS, S.C. (1982) : lnterferon induction in healthy and tumour bearing dogs by cell wallsof ·M.bovis, strain BCG. Am. J. Vet.Res: 43: 1232-1235.
  • YÜCEL, R. (1977) : Veteriner Şirurjide Transplantasyonlar. Fırat Üniver. Vet. · Fak. Der. 4: 80,96. :
There are 18 citations in total.

Details

Primary Language Turkish
Subjects Veterinary Surgery
Journal Section Original Article
Authors

Osman Erganiş This is me

Osman Kaya This is me

Publication Date December 1, 1990
Submission Date December 1, 1990
Published in Issue Year 1990 Volume: 6 Issue: 6

Cite

APA Erganiş, O., & Kaya, O. (1990). İmmunomodülatörler ve Kullanım Alanları. Etlik Veteriner Mikrobiyoloji Dergisi, 6(6), 147-172.

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