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Kanatlı Salmonella Aşılarına Farklı Perspektiften Bakış

Year 2008, Volume: 19 Issue: 1, 63 - 68, 01.06.2008

Abstract

Salmonella infeksiyonlarından korunmada aşılama oldukça güçlü bir araçtır. Daha etkili ve daha güvenli Salmonella aşılarının
geliştirilmesine ihtiyaç duyulmaktadır. Salmonella virulensinin genetiği hakkında elde edilen bilgiler ve modern rekombinant
DNA teknolojisi; çoklu, belirlenmiş, attenüe ve irreversible mutasyonların bakteri genomu içerisine dahil edilmesi gerekliliği üzerinde
durmaktadır. Bu genler bakteriyel yapısal komponentlerin (Lipopolisakkarit; LPS, dış membran proteini; outer membran proteini,
OMP) veya temel metabolitlerin (aromatik aminoasit, purin, primidinhistidin) biyosentezinden sorumlu olan ‘house-keeping genes’
olarak adlandırılan genlerdir. Salmonella’nın konak içinde hayatta kalabilmesini sağlayan çok sayıda gen identifiye edilmiştir. Bu
genlerde meydana getirilen mutasyonlarla yeni aşı suşları denenmiştir.

References

  • Barrow P. (1991). Serological analysis for antibodies to Salmonella enteritidis. Vet Rec. 128(2), 43-4.
  • Barrow PA, Hassan JO, Lovell MA, Berchieri A, (1990). Vaccination of chickens with aroA and other mutants of Salmonella typhimurium and Salmonella enteritidis. Res Microbiol. 141(7-8), 851-853.
  • Barrow PA, Tucker JF, Simpson JM, (1987). Inhibition of colonization of the chicken alimentary tract with Salmonella Typhimurium gram-negative facultatively anaerobic bacteria. Epidemiol Infect. 98, 311-22.
  • Bäumler AJ, Hargis BM and Tsolis RM, (2000). Tracing Origins of Salmonella outbreaks. Science. 287, 50-52.
  • Berchieri JRA, Barrow PA. (1990). Further studies on the inhibition of colonization of the chicken alimentary tract with Salmonella Typhimurium by pre-colonization with an avirulent mutant. Epidemiol Infect. 104 (3), 427-41.
  • Cooper GL, Venables LM, Nicholas RA, Cullen GA, Hormaeche CE, (1992). Vaccination of chickens with chicken-derived Salmonella enteritidis phage type 4 aroA live oral Salmonella vaccines. Vaccine.10(4), 247-254.
  • Cooper GL, Venables LM, Nicholas RA, Cullen GA, Hormaeche CE, (1993). Further studies of the application of live Salmonella enteritidis aroA vaccines in chickens. Vet Rec. 133(2), 31-36.
  • Cooper GL, Venables LM, Woodward MJ, Hormaeche CE, (1994). Invasiveness and persistence of Salmonella enteritidis, Salmonella typhimurium, and a genetically defined Salmonella enteritidis aroA strain in young chickens. Infect Immun. 62(11), 4739-46.
  • Dueger EL, House JK, Heithoff DM, Mahan MJ, (2001). Salmonella DNA Adenine methylase Mutants Elicit Protective Immune Responses to Homologous and Heterologous Serovars in Chickens. Infection and Immunity 69(12), 7950-7954.
  • Fields PI, Swanson RV, Haidaris CG, Heffron F, (1986). Mutants of Salmonella typhimurium that can not survive within the macrophage are avirulent. Proc Natl Acad Sci. U S A. 83(14), 5189-93.
  • Hassan JO, Curtiss III R, (1994). Development and evaluation of an experimental vaccination program using a live avirulent Salmonella typhimurium strain to protect immunized chickens against challenge with homologous and heterologous Salmonella serotypes. Infect Immun. 62(12), 5519-5527.
  • Hassan JO and R. Curtiss III, (1997). Efficiacy of a live avirulent Salmonella typhimurium vaccine in preventing colonization and invasion of laying hens by Salmonella typhimurium and Salmonella enteritidis. Avian Dis. 41, 783-791.
  • Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ, (1999). An essential role for DNA adenine methylation in bacterial virulence. Science. 284, 967-970.
  • Heithoff DM, Enuioutina EY, Daynes RA, Sinsheimer DA, Low DA, Mahan MJ, (2001). Salmonella DNA adenine methylase mutants confer cross-protective immunity. Infect. Immun. 69, 6725-6730.
  • Hoiseth SK and Stocker BA, (1981). Aromatic-dependent Salmonella typhimuriumare non-virulent and effective as live vaccines. Nature. 291, 238-9.
  • Khan MI, Fadl AA, Venkitanarayanan KS, (2003). Reducing colonization of Salmonella Enteritidis in chicken by targetting outer membran proteins. Journal of Applied Microbiology. 95, 142-145.
  • Low DA, Weyand NJ, Mahan MJ, (2001). The roles of DNA methylation in the control of bacterial gene expression and virulence. Infect. Immun. 69, 7197-7204.
  • Mahan MJ, Low DA, (2001). DNA methylation regulates bacterial gene expresiion and virulence. ASM News 67, 1-7.
  • Mastroeni P, Chabalgoity JA, Dunstan SJ, Maskell DJ, Dougan G, (2000). Salmonella: Immune responses and vaccines. The Veterinary Journal. 161, 132-164.
  • Meenakshi M, Bakshi CS, Butchaiah G, Bansal MP, Siddiqui MZ, Singh VP, (1999). Adjuvanted outer membrane protein vaccine protects poultry against infection with Salmonella enteritidis. Vet Res Commun. 23(2), 81- 90.
  • Nicholson B, Low DA, (2000). DNA methylationdependent regulation of pef expression in Salmonella typhimurium. Mol. Microbiol. 35, 728-742.
  • Silva EN, Snoeyenbos GH, Weinack OM, Smyser CF, (1981). Studies on the use of 9R strain of Salmonella gallinarum as a vaccine in chickens. Avian Dis. 25(1), 38-52.
  • Smith H.W. (1956). The use of live vaccines in experimental Salmonella gallinarum infection in chickens with observations on their interference effect. J Hyg (Lond). 54(3), 419-32.
  • van Immerseel F, de Buck Jeroen, de Smet I, Mast J, Haesebrouck F, Du Catelle R, (2002). The effect of vaccination with a Salmonella Enteritidis aroA mutant on early callular responses in caecal lamina propria of newly- hatched chickens. Vaccine. 20, 3034-3041.
  • van der Woude M, Braaten B, Low D, (1996). Epigenetic phase variation of thr pap operon in Escherichia coli. Trends Microbiol. 4, 5-9.
  • Wolfgang R, Hargis BM, Tsolis RM, Kingsley RA, Hinz KH, Tschäpe H. and Bäumler AJ, (2000). Competitive Exclusion of Salmonella Enteritidis by Salmonella Gallinarum in Poultry. Emerg Infect Dis. 6, 444-449.
  • Wray C, Sojka WJ, Pritchard DG, Morris JA, (1983). Immunization of animals with gal E mutants of "Salmonella typhimurium". Dev Biol Stand. 53, 41-6.
  • Zhang-Barber L, Turner A.K, Barrow P.A. (1999). Vaccination for Control Salmonella in poultry. Vaccine. 17, 2538-2545.
  • Zhang-Barber L, Turner AK, Martin G, Frankel G, Dougan G, Barrow PA, (1997). Influence of genes encoding proton-translocating enzymes on suppression of Salmonella Typhimurium growth and colonization. J. Bacteriol. 179(22), 7186-7190.

View at Poultry Salmonella Vaccines With Different Perspective

Year 2008, Volume: 19 Issue: 1, 63 - 68, 01.06.2008

Abstract

Vaccination is a powerful tool for the protection of Salmonella infections. There is a need to develop more effective
and more reliable Salmonella vaccines. The knowledge achieved about the genetics of Salmonella virulence and modern recombinant
DNA technology dwell upon a subject of the necessity of inserting multiple, specified, attenued and irreversible mutations into the
bacterial genome. These genes, responsible for biosynthesis of bacterial basic structural components (Lipopolisaccharide; LPS, outer
membran protein; OMP) or basic metabolits (aromatic aminoasit, purin, primidinhistidin) are termed as house-keeping genes. Many
genes, eliciting survival of Salmonella into the host were identified. New vaccine strains were experienced by the mutations achieved
in the genes.

References

  • Barrow P. (1991). Serological analysis for antibodies to Salmonella enteritidis. Vet Rec. 128(2), 43-4.
  • Barrow PA, Hassan JO, Lovell MA, Berchieri A, (1990). Vaccination of chickens with aroA and other mutants of Salmonella typhimurium and Salmonella enteritidis. Res Microbiol. 141(7-8), 851-853.
  • Barrow PA, Tucker JF, Simpson JM, (1987). Inhibition of colonization of the chicken alimentary tract with Salmonella Typhimurium gram-negative facultatively anaerobic bacteria. Epidemiol Infect. 98, 311-22.
  • Bäumler AJ, Hargis BM and Tsolis RM, (2000). Tracing Origins of Salmonella outbreaks. Science. 287, 50-52.
  • Berchieri JRA, Barrow PA. (1990). Further studies on the inhibition of colonization of the chicken alimentary tract with Salmonella Typhimurium by pre-colonization with an avirulent mutant. Epidemiol Infect. 104 (3), 427-41.
  • Cooper GL, Venables LM, Nicholas RA, Cullen GA, Hormaeche CE, (1992). Vaccination of chickens with chicken-derived Salmonella enteritidis phage type 4 aroA live oral Salmonella vaccines. Vaccine.10(4), 247-254.
  • Cooper GL, Venables LM, Nicholas RA, Cullen GA, Hormaeche CE, (1993). Further studies of the application of live Salmonella enteritidis aroA vaccines in chickens. Vet Rec. 133(2), 31-36.
  • Cooper GL, Venables LM, Woodward MJ, Hormaeche CE, (1994). Invasiveness and persistence of Salmonella enteritidis, Salmonella typhimurium, and a genetically defined Salmonella enteritidis aroA strain in young chickens. Infect Immun. 62(11), 4739-46.
  • Dueger EL, House JK, Heithoff DM, Mahan MJ, (2001). Salmonella DNA Adenine methylase Mutants Elicit Protective Immune Responses to Homologous and Heterologous Serovars in Chickens. Infection and Immunity 69(12), 7950-7954.
  • Fields PI, Swanson RV, Haidaris CG, Heffron F, (1986). Mutants of Salmonella typhimurium that can not survive within the macrophage are avirulent. Proc Natl Acad Sci. U S A. 83(14), 5189-93.
  • Hassan JO, Curtiss III R, (1994). Development and evaluation of an experimental vaccination program using a live avirulent Salmonella typhimurium strain to protect immunized chickens against challenge with homologous and heterologous Salmonella serotypes. Infect Immun. 62(12), 5519-5527.
  • Hassan JO and R. Curtiss III, (1997). Efficiacy of a live avirulent Salmonella typhimurium vaccine in preventing colonization and invasion of laying hens by Salmonella typhimurium and Salmonella enteritidis. Avian Dis. 41, 783-791.
  • Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ, (1999). An essential role for DNA adenine methylation in bacterial virulence. Science. 284, 967-970.
  • Heithoff DM, Enuioutina EY, Daynes RA, Sinsheimer DA, Low DA, Mahan MJ, (2001). Salmonella DNA adenine methylase mutants confer cross-protective immunity. Infect. Immun. 69, 6725-6730.
  • Hoiseth SK and Stocker BA, (1981). Aromatic-dependent Salmonella typhimuriumare non-virulent and effective as live vaccines. Nature. 291, 238-9.
  • Khan MI, Fadl AA, Venkitanarayanan KS, (2003). Reducing colonization of Salmonella Enteritidis in chicken by targetting outer membran proteins. Journal of Applied Microbiology. 95, 142-145.
  • Low DA, Weyand NJ, Mahan MJ, (2001). The roles of DNA methylation in the control of bacterial gene expression and virulence. Infect. Immun. 69, 7197-7204.
  • Mahan MJ, Low DA, (2001). DNA methylation regulates bacterial gene expresiion and virulence. ASM News 67, 1-7.
  • Mastroeni P, Chabalgoity JA, Dunstan SJ, Maskell DJ, Dougan G, (2000). Salmonella: Immune responses and vaccines. The Veterinary Journal. 161, 132-164.
  • Meenakshi M, Bakshi CS, Butchaiah G, Bansal MP, Siddiqui MZ, Singh VP, (1999). Adjuvanted outer membrane protein vaccine protects poultry against infection with Salmonella enteritidis. Vet Res Commun. 23(2), 81- 90.
  • Nicholson B, Low DA, (2000). DNA methylationdependent regulation of pef expression in Salmonella typhimurium. Mol. Microbiol. 35, 728-742.
  • Silva EN, Snoeyenbos GH, Weinack OM, Smyser CF, (1981). Studies on the use of 9R strain of Salmonella gallinarum as a vaccine in chickens. Avian Dis. 25(1), 38-52.
  • Smith H.W. (1956). The use of live vaccines in experimental Salmonella gallinarum infection in chickens with observations on their interference effect. J Hyg (Lond). 54(3), 419-32.
  • van Immerseel F, de Buck Jeroen, de Smet I, Mast J, Haesebrouck F, Du Catelle R, (2002). The effect of vaccination with a Salmonella Enteritidis aroA mutant on early callular responses in caecal lamina propria of newly- hatched chickens. Vaccine. 20, 3034-3041.
  • van der Woude M, Braaten B, Low D, (1996). Epigenetic phase variation of thr pap operon in Escherichia coli. Trends Microbiol. 4, 5-9.
  • Wolfgang R, Hargis BM, Tsolis RM, Kingsley RA, Hinz KH, Tschäpe H. and Bäumler AJ, (2000). Competitive Exclusion of Salmonella Enteritidis by Salmonella Gallinarum in Poultry. Emerg Infect Dis. 6, 444-449.
  • Wray C, Sojka WJ, Pritchard DG, Morris JA, (1983). Immunization of animals with gal E mutants of "Salmonella typhimurium". Dev Biol Stand. 53, 41-6.
  • Zhang-Barber L, Turner A.K, Barrow P.A. (1999). Vaccination for Control Salmonella in poultry. Vaccine. 17, 2538-2545.
  • Zhang-Barber L, Turner AK, Martin G, Frankel G, Dougan G, Barrow PA, (1997). Influence of genes encoding proton-translocating enzymes on suppression of Salmonella Typhimurium growth and colonization. J. Bacteriol. 179(22), 7186-7190.
There are 29 citations in total.

Details

Primary Language Turkish
Subjects Veterinary Surgery
Journal Section Review
Authors

Elçin Günaydın This is me

Publication Date June 1, 2008
Submission Date December 1, 2008
Published in Issue Year 2008 Volume: 19 Issue: 1

Cite

APA Günaydın, E. (2008). Kanatlı Salmonella Aşılarına Farklı Perspektiften Bakış. Etlik Veteriner Mikrobiyoloji Dergisi, 19(1), 63-68.

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