Determination of Nutritional Status, Biochemical Parameters and Stroke Severity in Acute Ischemic Stroke Patients: A Cross-Sectional Study

Year 2024, Volume: 4 Issue: 3, 496 - 513, 31.12.2024

Yunus Emre Bakirhan , Burcu Ateş Özcan , Hasan Hüseyin Karadeli

https://doi.org/10.56061/fbujohs.1479645

Abstract

Nutritional problems and nutritional deficiencies resulting from impaired consciousness, dysphagia, fatique and perceptual disturbances can frequently be observed in ischemic stroke patients after acute stroke. Weight loss in patients with dysphagia can often cause malnutrition. This study was conducted to determine the severity of stroke and nutritional status in acute ischemic stroke patients and to screen the risk of malnutrition. In this study, the nutritional status of ischemic stroke patients was evaluated with NRI and NRS 2002 and some biochemical parameters were examined from the patient file. All patients had moderate to severe ischaemic stroke (NIHSS: 9.9±2.51) and the majority were at risk of malnutrition according to NRS 2002 (92.3% vs. 93.8%, p=0.55). The majority of acute ischaemic stroke patients were found to be moderately malnourished (moderate risk, 52.4%), followed by mild malnutrition risk (23.8%) according to NRI risk score. Patients had low levels of albumin (3.1±0.58 g/dL), prealbumin (13.0±5.40 mg/dL), and hemoglobin (11.6±2.34 g/dL). Total cholesterol (188.7±35.43), triglycerides (134.2±57.43 mg/dL), and LDL (118.7±31.42 mg/dL) were within normal limits, while HbA1c (6.8±2.40) and fasting plasma glucose (150.0±69.00 mg/dL) levels were high. As a result, this study highlights the importance of malnutrition assessment and monitoring of biochemical parameters.

Keywords

Acute ischemic stroke, biochemical parameters, malnutrition, nutritional status

Ethical Statement

The study protocol was approved by the Ministry of Health Istanbul Medeniyet University Göztepe Training and Research Hospital Clinical Research Ethics Committee with decision number 2022/0723 and was conducted in accordance with the ethical principles of the Declaration of Helsinki.

Supporting Institution

Marmara University

Project Number

11069

Thanks

This study was carried out with the support of project ID number 11069, approved by Marmara University Scientific Research Projects Commission.

Akut İskemik İnme Hastalarında Beslenme Durumunun, Biyokimyasal Parametrelerin ve İnme Şiddetinin Belirlenmesi: Kesitsel Bir Çalışma

Abstract

Akut inme sonrası iskemik inme hastalarında bilinç bozukluğu, disfaji, yorgunluk ve algı bozukluklarından kaynaklanan beslenme sorunları ve beslenme yetersizlikleri sıklıkla görülebilmektedir. Disfajili hastalarda gelişen ağırlık kaybı sıklıkla malnütrisyona neden olabilmektedir. Bu çalışma, akut iskemik inme hastalarında inme şiddetini ve beslenme durumunu belirlemek ve malnütrisyon riskini saptamak amacıyla yapılmıştır. İskemik inme hastalarının beslenme durumu NRI ve NRS 2002 ile değerlendirilmiş ve bazı biyokimyasal parametreleri hasta dosyasından alınarak incelenmiştir. Tüm hastalarda orta ila şiddetli iskemik inme vardı (NIHSS: 9.9±2.51) ve NRS 2002'ye göre hastaların çoğunluğu malnütrisyon riski altındaydı (%92,3'e karşı %93,8, p=0,55). NRI risk skoruna göre hastaların büyük bir çoğunluğunun orta derecede malnütrisyonlu (%52,4) olduğu bunu hafif malnütrisyon riskinin (%23,8) takip ettiği görülmüştür. Hastaların albümin (3,1±0,58 g/dL), prealbumin (13,0±5,40 mg/dL) ve hemoglobin (11,6±2,34 g/dL) düzeyleri düşük bulunmuştur. Total kolesterol (188,7±35,43), trigliserid (134,2±57,43 mg/dL) ve LDL (118,7±31,42 mg/dL) seviyeleri normal sınırlarda bulunurken, HbA1c (6,8±2,40) ve açlık plazma glukozu (150,0±69,00 mg/dL) dL) yüksek bulunmuştur. Sonuç olarak, bu çalışma malnütrisyon değerlendirmesinin ve biyokimyasal parametrelerin izlenmesinin önemini vurgulamaktadır.

Keywords

Beslenme durumu, biyokimyasal parametreler, akut iskemik inme, malnütrisyon

Project Number

11069

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