Analysis of C-reactive protein in pyelonephritis

Mithaq Al-nassary; Mazin Ameen; Batoll Mutar Mahdi

Piyelonefritte C-reaktif protein analizi

Year 2011, Volume: 17 Issue: 3, 126 - 128, 01.04.2011

Mithaq Al-nassary Mazin Ameen Batoll Mutar Mahdi

Abstract

Urinary tract infection especially pyelonephritis is a common condition worldwide caused by different uropathogens. The hostresponse parameters like C-reactive protein (CRP) are important inflammatory markers and diagnostic tests. The aim of this study was to assess the usefulness of CRP in urinary tract infection- pyelonephritis caused by different bacteria for defining the urinary tract infection (UTI). A total of fifty patients with clinical symptoms of pyelonephritis referred to Al-Kindi Teaching Hospital (Baghdad, Iraq), were investigated from October 2009 to November 2009. Clean-catch midstream urine of the patients was collected. Urine specimens were cultured for isolation of the microbial agents of UTI. The isolated bacteria were identified using biochemical tests. CRP were assessed in relation to the inflammatory responses. The most common isolated bacteria were Escherichia coli (40%), Enterobacter (20%) and Klebsiella (12%). The least frequent bacteria were Staphylococcus aureus (4%), Staphylococcus pyogenes (4%)and Staphylococcus fecalis (4%). There was a significant difference (P

Keywords

References

1. Stamm WE, Hooton TM. Management of urinary tract infections in adults. N Engl J Med 1993;329(18):1328-34
2. Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Dis Mon 2003;49(2):53-70
3. Amin M, Mehdinejad M, Pourdangchi Z. Study of bacteria isolated from urinary tract infections and determination of their susceptibility to antibiotics. Jundishapur Journal of Microbiology 2009;2(3):118-23
4. Jodal U. The immune response to urinary tract infections in childhood. I. Serological diagnosis of primary symptomatic infection in girls by indirect hemagglutination. Acta Paediatr Scand 1975;64(1):96-104
5. Pylkkanen J. Antibody-coated bacteria in the urine of infants and children with their first two urinary tract infections. Acta Paediatr Scand 1978;67(3):275-9
6. Craig JC, Wheeler DM, Irwig L, Howman-Giles RB. How accurate is dimercaptosuccinic acid scintigraphy for the diagnosis of acute pyelonephritis? A meta-analysis of experimental studies. J Nucl Med 2000;41(6):986-93
7. Jodal U, Lindberg U, Lincoln K. Level diagnosis of symptomatic urinary tract infections in childhood. Acta Paediatr Scand 1975;64(2):201-8
8. Morris MW, Davey FR. Basic examination of blood. In: Henry JB, editor. Clinical diagnosis and management by laboratory methods. 12th ed. Philadelphia: WB Saunders; 2001; 479-519
9. Hutchison RE, Davey FR. Leukocytic disorders. In: Henry JB, editor. Clinical diagnosis and management by laboratory methods. 12th ed. Philadelphia: WB Saunders; 2001; 586-622
10. Jodal U, Hanson LA. Sequential determination of C-reactive protein in acute childhood pyelonephritis. Acta Paediatr Scand 1976;65(3):319-22
11. Hellerstein S, Duggan E, Welchert E, Mansour F. Serum Creactive protein and the site of urinary tract infections. J Pediatr 1982;100(1):21-5
12. Forbes BA. Sahm DF, Weissfeld AS. Bailey and Scott's Diagnostic Microbiology, 12th edition, Mosby Elsevier, 2007; 842-55
13. Mandell GL, Bennett JE Dolin R. Principles and practice of infectious diseases. Churchill Livingstone, 2005; 881-2
14. MacFaddin JF. Biochemical tests for identification of medical bacteria. 3rd ed. Philadelphia: Lippincott Williams and Wilkins, 2000
15. McPherson RA, Ben-Ezra J, Zhao S. Basic examination of urine. In: McPherson RA, Pincus MR, editors. Henry’s clinical diagnosis and management by laboratory methods. 21st ed
Philadelphia: Saunders Elsevier; 2007; 394-424
16. Peltola H, Rasanen JA. Quantitative C-reactive protein in relation to erythrocyte sedimentation rate, fever, and duration of antimicrobial therapy in bacteraemic diseases of childhood. J Infect. 1982;5(3):257-67
17. Lin DS, Huang SH, Lin CC, Tung YC, Huang TT, Chiu NC, et al. Urinary tract infection in febrile infants younger than eight weeks of Age. Pediatrics 2000;105(2):E20
18. Garin EH, Olavarria F, Araya C, Broussain M, Barrera C, Young L. Diagnostic significance of clinical and laboratory findings to localize site of urinary infection. Pediatr Nephrol 2007;22(7):1002-6
19. Ayazi P, Mahyar A, Hashemi HJ, Daneshi MM, Karimzadeh T, Salimi F. Comparison of procalcitonin and C-reactive protein tests in children with urinary tract infection. Iran J Pediatr 2009;19(4):381-6
20. Meyrier A. Diagnosis and management of renal infections. Curr Opin Nephrol Hypertens 1996;5(2):151-7
21. Astal ZY, Sharif FA. Relationship between demographic characteristics and community-acquired urinary tract infection
East Mediterr Health J 2002;8(1):164-71
22. Kothari A, Sagar V. Antibiotic resistance in pathogens causing community-acquired urinary tract infections in India: a multicenter study. J Infect Dev Ctries 2008;2(5):354-8

Analysis of C-reactive protein in pyelonephritis

Year 2011, Volume: 17 Issue: 3, 126 - 128, 01.04.2011

Mithaq Al-nassary Mazin Ameen Batoll Mutar Mahdi

Abstract

Üriner kanal enfeksiyonu özellikle piyelonefrit farklı üropatojenlerin neden olduğu yaygın bir durumdur. C-reaktif protein (CRP) gibi vücut yanıt parametreleri önemli inflamatuar belirteç ve diagnostik testidirler. Bu çalışmanın amacı, üriner kanal enfeksiyonunu tanımlamak için farklı bakterilerin neden olduğu üriner kanal enfeksiyonu piyelonefritte CRP'nin faydasını saptamaktı. Al-Kindi Eğitim Hastanesi'ne (Bağdat, Irak) başvuran piyelonefrit klinik semptomlu 50 hasta, Ekim 2009'dan Kasım 2009'a kadar araştırıldı. Hastaların idrarları temiz bir şekilde toplandı. Üriner kanal enfeksiyonu için mikrobiyal ajanların izolasyonu için idrar örneklerinin kültürü yapıldı. İzole edilen bakteriler biyokimyasal testler kullanılarak tanımlandı. İnflamatuar yanıta ilişkili olarak CRP ölçüldü. En yaygın izole edilen bakteriler, Escherichia coli(%40), Enterobacter (%20) ve Klebsiella (%12) idi. En az sıklıkta görülen bakteriler,Staphylococcus aureus (%4), Staphylococcus pyogenes (%4) ve Staphylococcus fecalis (%4) idi. Sistemik inflamatuar yanıt (CRP) ile üriner kanal inflamatuar yanıt (piyüri) arasında anlamlı fark (P

Keywords

Bakteriyel ajanlar, C-reaktif protein, enfeksiyon, piyelonefrit, üriner

References

1. Stamm WE, Hooton TM. Management of urinary tract infections in adults. N Engl J Med 1993;329(18):1328-34
2. Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Dis Mon 2003;49(2):53-70
3. Amin M, Mehdinejad M, Pourdangchi Z. Study of bacteria isolated from urinary tract infections and determination of their susceptibility to antibiotics. Jundishapur Journal of Microbiology 2009;2(3):118-23
4. Jodal U. The immune response to urinary tract infections in childhood. I. Serological diagnosis of primary symptomatic infection in girls by indirect hemagglutination. Acta Paediatr Scand 1975;64(1):96-104
5. Pylkkanen J. Antibody-coated bacteria in the urine of infants and children with their first two urinary tract infections. Acta Paediatr Scand 1978;67(3):275-9
6. Craig JC, Wheeler DM, Irwig L, Howman-Giles RB. How accurate is dimercaptosuccinic acid scintigraphy for the diagnosis of acute pyelonephritis? A meta-analysis of experimental studies. J Nucl Med 2000;41(6):986-93
7. Jodal U, Lindberg U, Lincoln K. Level diagnosis of symptomatic urinary tract infections in childhood. Acta Paediatr Scand 1975;64(2):201-8
8. Morris MW, Davey FR. Basic examination of blood. In: Henry JB, editor. Clinical diagnosis and management by laboratory methods. 12th ed. Philadelphia: WB Saunders; 2001; 479-519
9. Hutchison RE, Davey FR. Leukocytic disorders. In: Henry JB, editor. Clinical diagnosis and management by laboratory methods. 12th ed. Philadelphia: WB Saunders; 2001; 586-622
10. Jodal U, Hanson LA. Sequential determination of C-reactive protein in acute childhood pyelonephritis. Acta Paediatr Scand 1976;65(3):319-22
11. Hellerstein S, Duggan E, Welchert E, Mansour F. Serum Creactive protein and the site of urinary tract infections. J Pediatr 1982;100(1):21-5
12. Forbes BA. Sahm DF, Weissfeld AS. Bailey and Scott's Diagnostic Microbiology, 12th edition, Mosby Elsevier, 2007; 842-55
13. Mandell GL, Bennett JE Dolin R. Principles and practice of infectious diseases. Churchill Livingstone, 2005; 881-2
14. MacFaddin JF. Biochemical tests for identification of medical bacteria. 3rd ed. Philadelphia: Lippincott Williams and Wilkins, 2000
15. McPherson RA, Ben-Ezra J, Zhao S. Basic examination of urine. In: McPherson RA, Pincus MR, editors. Henry’s clinical diagnosis and management by laboratory methods. 21st ed
Philadelphia: Saunders Elsevier; 2007; 394-424
16. Peltola H, Rasanen JA. Quantitative C-reactive protein in relation to erythrocyte sedimentation rate, fever, and duration of antimicrobial therapy in bacteraemic diseases of childhood. J Infect. 1982;5(3):257-67
17. Lin DS, Huang SH, Lin CC, Tung YC, Huang TT, Chiu NC, et al. Urinary tract infection in febrile infants younger than eight weeks of Age. Pediatrics 2000;105(2):E20
18. Garin EH, Olavarria F, Araya C, Broussain M, Barrera C, Young L. Diagnostic significance of clinical and laboratory findings to localize site of urinary infection. Pediatr Nephrol 2007;22(7):1002-6
19. Ayazi P, Mahyar A, Hashemi HJ, Daneshi MM, Karimzadeh T, Salimi F. Comparison of procalcitonin and C-reactive protein tests in children with urinary tract infection. Iran J Pediatr 2009;19(4):381-6
20. Meyrier A. Diagnosis and management of renal infections. Curr Opin Nephrol Hypertens 1996;5(2):151-7
21. Astal ZY, Sharif FA. Relationship between demographic characteristics and community-acquired urinary tract infection
East Mediterr Health J 2002;8(1):164-71
22. Kothari A, Sagar V. Antibiotic resistance in pathogens causing community-acquired urinary tract infections in India: a multicenter study. J Infect Dev Ctries 2008;2(5):354-8

There are 24 citations in total.

Details

Primary Language	Turkish
Journal Section	Articles
Authors	Mithaq Al-nassary This is me Mazin Ameen This is me Batoll Mutar Mahdi This is me
Publication Date	April 1, 2011
Published in Issue	Year 2011 Volume: 17 Issue: 3

Cite

APA	Al-nassary, M., Ameen, M., & Mahdi, B. M. (2011). Analysis of C-reactive protein in pyelonephritis. Gaziantep Medical Journal, 17(3), 126-128.
AMA	Al-nassary M, Ameen M, Mahdi BM. Analysis of C-reactive protein in pyelonephritis. Gaziantep Medical Journal. April 2011;17(3):126-128.
Chicago	Al-nassary, Mithaq, Mazin Ameen, and Batoll Mutar Mahdi. “Analysis of C-Reactive Protein in Pyelonephritis”. Gaziantep Medical Journal 17, no. 3 (April 2011): 126-28.
EndNote	Al-nassary M, Ameen M, Mahdi BM (April 1, 2011) Analysis of C-reactive protein in pyelonephritis. Gaziantep Medical Journal 17 3 126–128.
IEEE	M. Al-nassary, M. Ameen, and B. M. Mahdi, “Analysis of C-reactive protein in pyelonephritis”, Gaziantep Medical Journal, vol. 17, no. 3, pp. 126–128, 2011.
ISNAD	Al-nassary, Mithaq et al. “Analysis of C-Reactive Protein in Pyelonephritis”. Gaziantep Medical Journal 17/3 (April 2011), 126-128.
JAMA	Al-nassary M, Ameen M, Mahdi BM. Analysis of C-reactive protein in pyelonephritis. Gaziantep Medical Journal. 2011;17:126–128.
MLA	Al-nassary, Mithaq et al. “Analysis of C-Reactive Protein in Pyelonephritis”. Gaziantep Medical Journal, vol. 17, no. 3, 2011, pp. 126-8.
Vancouver	Al-nassary M, Ameen M, Mahdi BM. Analysis of C-reactive protein in pyelonephritis. Gaziantep Medical Journal. 2011;17(3):126-8.

Article Files

Full Text