Ürdün'de çocukluk çağı fokal epilepsilerin klinik profili

Year 2011, Volume: 17 Issue: 3, 129 - 132, 01.04.2011

Wael Hayel Khreisat

Abstract

Bu çalışma, çocukluk çağı fokal epilepsilerin bazal profilini ortaya koymak için yapıldı. Bu çalışmaya katılan olgular, Ürdün'de Kraliçe Rania Çocuk Hastanesi Pediatrik Nöroloji Kliniği'ne başvuran 2 yaş üzeri fokal epilepsili çocuklardı. Yaş, cinsiyet, nöbet tipinin detayı, ilk uyarılmamış nöbet yaşı, nöbetlerin aile hikayesi, febril nöbetlerin hikayesi, etyolojik, sosyoekonomik sınıf, ilave nörolojik bozukluk, elektroensefalografi (EEG) ve beyin görüntüleme bulguları, ve antiepileptic ilaç kullanımı verileri toplandı, sonuçlar daha ileriki çalışma için kaydedildi. Bu çalışmaya total 100 fokal epilepsili vaka alındı, bunların 59'u erkekti. Basit parsiyet tip %48'inde, sekonder generalizeli basit parsiyel %17'inde ve kompleks parsiyel nöbetler %35'inde kaydedildi. Parsiyel başlangıçlı nöbetlerin pik yaptığı yaş 11-14 idi ve kompleks parsiyel nöbetler 6-10 yaşları arasındaydı. Yirmi altı hastada epilepsinin aile hikayesi vardı, %91'i düşük sosyoekenomik sınıftandı. Hastaların %13'ünde febril nöbet hikayesi varken semptomatik epilepsi %48'inde vardı. Yirmi beş çocuk hipoksik-iskemik ensefalopatiliydi. En yaygın nörolojik bozukluk %35 ile öğrenme güçlüğü idi. EEG %20'inde normaldi ve %68'inde monoterapi kullanıldı ve %33'ünde kötü kontrol (tedaviye cevap vermeyen) vardı. Bizim ülkemizde fokal epilepsilerin şekli gelişmiş ülkelerdekinden farklı değildir, etyolojinin belirlenmesi önleme planı için önemlidir.

Keywords

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Clinical profile of childhood focal epilepsies in Jordan

Abstract

The present study was done in order to obtain a baseline profile of childhood focal epilepsies. Subjects included in this study were children suffering from focal epilepsy with age above 2 years who attended the Pediatric Neurology Clinic in Queen Rania Hospital for Children in Jordan. The data were obtained: age, sex, detailed of seizures type, age at first unprovoked seizure, family history of seizures, history of febrile seizures, etiological, socioeconomic class, additional neuro-impairment, electroencephalography (EEG) and brain imaging finding and the use of antiepileptic drugs, the results were recorded for further study. A total of 100 cases of focal epilepsy were enrolled in the study, 59 were male. Simple partial type recorded in 48%, simple partial with secondary generalization in 17% and complex partial seizure in 35%. In partial onset seizures the peak age was between 11-14 years and complex partial seizures between ages 6-10 years. Twenty-six patients had a family history of epilepsy, 91% of low socioeconomic class. Thirteen % of cases have history of febrile seizures, while symptomatic epilepsy was found in 48%. Twenty-five children had hypoxic-ischemic encephalopathy. The most common neurological impairment was learning difficulties with 35%. EEG was normal in 20% and monotherapy was used in 68% and 33% had bad control (intractable). The pattern of focal epilepsies in our country do not differ from that of developed countries, identifying the etiology is important to plan prevention.

Keywords

Kompleks parsiyel nöbet, epilepsi, basit parsiyel nöbet

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