Case Report
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Dental apseyi taklit eden bir patoloji: fasiyal pleksiform nörofibroma

Year 2019, , 28 - 32, 02.01.2019
https://doi.org/10.17214/gaziaot.408607

Abstract



















Tanıtım: Fasiyal pleksiform nörofibroma (FPN) yüzün nadir görülen
tümörlerinden biridir. Kranial sinirler veya üst servikal sinirleri içerir ve
lezyon düşük oranda malign transformasyon gösterir. Özellikle çocukluk çağında
izlenir.
FPN aynı zamanda nörofibromatozis tip 1 (NF1) için tanı
kriterlerinden biridir. NF1 yaygın ve multisistemik bir sendromdur. Bu olgu
raporunda, çocuk hastada FPN ile birlikte izlenen NF1'in oral ve radyografik bulgularının
sunulması amaçlandı.

Olgu Bildirimi: Dokuz yaşındaki NF1
tanılı erkek hasta sol mandibuler posterior bölgede yemek yerken gelişen ağrı
şikayetiyle kliniğimize başvurdu. Ekstraoral muayenede ‘cafe-au-lait’ lekeleri
ve sol yanakta ağrısız şişlik görüldü. Şişliğin palpasyonunda solucan torbası
hissi alındı. İntraoral muayenede sol bukkal mukozada şişlik, alveoler kemikte
genişleme ve bütün süt molar dişlerde çürükler olduğu saptandı. Periapikal
radyografta 75 numaralı dişte enfeksiyon ve buna bağlı olarak distal kök rezorpsiyonu
belirlendi. Panoramik radyografta mandibuler ramusta incelme, mandibuler kanal
ağzında genişleme, mandibuler çentikte derinleşme ve koronoid proçeste ve
kondil boynunda uzama izlendi. Alınan anamnez ve yapılan klinik ve radyografik
muayene sonucunda yanaktaki şişliğin dental apseye bağlı olmadığı bununla
birlikte bunun bir FPN lezyonu olduğu belirlendi. Hastanın gereken diş
tedavileri yapıldı ve rutin kontrol randevuları oluşturuldu.





Sonuç: Çocuk diş
hekimliğinde fasiyal asimetrilerin klinik olarak değerlendirilmesinde dental
patolojiler dışında kalan oluşumlara FPN’nin de sebep olabileceği akılda
tutulmalıdır.

References

  • National Institutes of Health Consensus Development Conference. Neurofibromatosis Conference Statement. Arch Neurol 1988;45:575-80.
  • Evans DG, Howard E, Giblin C, Clancy T, Spencer H, Huson SM, et al. Birth incidence and prevalence of tumor-prone syndromes: estimates from a UK family genetic register service. Am J Med Genet A 2010;152:327-32.
  • D'Ambrosio JA, Langlais RP, Young, RS. Jaw and skull changes in neurofibromatosis. Oral Surg Oral Med Oral Pathol 1988;66:391-6.
  • Shapiro SD, Abramovitch K, Van Dis ML, Skoczylas LJ, Langlais RP, et al. Neurofibromatosis: oral and radiographic manifestations. Oral Surg Oral Med Oral Pathol 1984;58:493-8.
  • Visnapuu V, Peltonen S, Tammisalo T, Peltonen J, Happonen, RP. Radiographic findings in the jaws of patients with neurofibromatosis 1. J Oral Maxillofac Surg 2012;70:1351-7.
  • Cunha KSG, Barboza EP, Dias EP, Oliveira FM. Neurofibromatosis type I with periodontal manifestation. A case report and literature review. Br Dent J 2004;196:457-60.
  • Patil K, Mahima VG, Shetty SK, Lahari K. Facial plexiform neurofibroma in a child with neurofibromatosis type I: A case report. J Indian Soc Pedod Prev Dent 2007;25:30-5.
  • Stefano PC, Apa SN, Lanoël AM, María, JS, Sierre S, Pierini AM. Isolated plexiform neurofibroma mimicking a vascular lesion. An Bras Dermatol 2016;91:240-2.
  • Friedrich RE, Giese M, Schmelzle R, Mautner VF, Scheuer HA. Jaw malformations plus displacement and numerical aberrations of teeth in neurofibromatosis type 1: a descriptive analysis of 48 patients based on panoramic radiographs and oral findings. J Craniomaxillofac Surg 2003;31:1-9.
  • Cunha KS, Rozza-de-Menezes RE, Andrade RM, Almeida L, Janini M, Geller M. Oral manifestations of neurofibromatosis type 1 in children with facial plexiform neurofibroma: report of three cases. J Clin Pediatr Dent 2015;39:168-71.
  • Sigillo R, Rivera H, Nikitakis NG, Sauk JJ. Neurofibromatosis type 1: a clinicopathological study of the orofacial manifestations in 6 pediatric patients. Pediatr Dent 2002;24:575-80.
  • Fadda MT, Verdino G, Mustazza MC, Bartoli D, Iannetti G. Intra-parotid facial nerve multiple plexiform neurofibroma in patient with NF1. Int J Pediatr Otorhinolaryngol 2008;72:553-7.
  • McGuirt WF, Johnson PE, McGuirt WT. Intraparotid facial nerve neurofibromas. Laryngoscope 2003;113:82-4.
  • Waggoner DJ, Towbin J, Gottesman G, Gutmann DH. Clinic-based study of plexiform neurofibromas in neurofibromatosis 1. Am J Med Genet A 2000;92:132-5.
  • Bardellini E, Amadori F, Flocchini P, Conti G, Piana G, Majorana A. Oral findings in 50 children with neurofibromatosis type 1. A case control study. Eur J Paediatr Dent 2011;12:256-60.
  • O'Driscoll, PM. The oral manifestations of multiple neurofibromatosis. Br J Oral Surg 1965;3:22-31.
  • Friedrich RE, Giese M, Stelljes C, Froeder C, Scheuer HA. Size of tooth crowns and position of teeth concerning the extension of facial plexiform neurofibroma in patients with neurofibromatosis type 1. Anticancer Res 2012;32:2207-14.

A pathology mimicking dental abscess: facial plexiform neurofibroma

Year 2019, , 28 - 32, 02.01.2019
https://doi.org/10.17214/gaziaot.408607

Abstract

Introduction: Facial plexiform neurofibroma (FPN) is a rare
tumor appearing on the face. It involves cranial or upper cervical nerves, and
lesions show malign transformation at a low rate. It is especially seen in childhood.
FPN is also a component of the diagnostic criteria for neurofibromatosis type 1
(NF1). NF1 is a common and multi-systemic syndrome. This case report aimed to
present the oral and radiographic findings of FPN and NF1 diagnosed in a child
patient.

Case Report: A 9-year-old
male patient diagnosed with NF1 applied to our clinic complaining from pain
during eating in the left mandibular posterior region. Extraoral examination
showed ‘cafe-au-lait’ blots and an asymptomatic swelling on the left cheek.
Worm-bag-sensation was felt on palpation of the swelling. Intraoral examination
showed swelling of the buccal mucosa, enlargement in the alveolar ridge and caries
on all primary molar teeth. Periapical radiograph showed signs of infection and
distal root resorption in tooth number 75. Panoramic radiograph revealed
thinning of the mandibular ramus, dilatation of the mandibular foramen,
deepening of the mandibular notch and prolongation of the coronoid process and condylar
neck. The collected anamnesis together with the clinical and radiographical
findings suggested that the swelling on the cheek was not due to a dental
abscess; rather it was due to an FPN lesion. The patient's treatment was done
and routine check-up appointments were arranged.





Conclusion: During clinical evaluation, it should be
kept in mind that FPN may be one of the reasons of facial asymmetries of
non-odontogenic pathologies in pediatric dentistry.

References

  • National Institutes of Health Consensus Development Conference. Neurofibromatosis Conference Statement. Arch Neurol 1988;45:575-80.
  • Evans DG, Howard E, Giblin C, Clancy T, Spencer H, Huson SM, et al. Birth incidence and prevalence of tumor-prone syndromes: estimates from a UK family genetic register service. Am J Med Genet A 2010;152:327-32.
  • D'Ambrosio JA, Langlais RP, Young, RS. Jaw and skull changes in neurofibromatosis. Oral Surg Oral Med Oral Pathol 1988;66:391-6.
  • Shapiro SD, Abramovitch K, Van Dis ML, Skoczylas LJ, Langlais RP, et al. Neurofibromatosis: oral and radiographic manifestations. Oral Surg Oral Med Oral Pathol 1984;58:493-8.
  • Visnapuu V, Peltonen S, Tammisalo T, Peltonen J, Happonen, RP. Radiographic findings in the jaws of patients with neurofibromatosis 1. J Oral Maxillofac Surg 2012;70:1351-7.
  • Cunha KSG, Barboza EP, Dias EP, Oliveira FM. Neurofibromatosis type I with periodontal manifestation. A case report and literature review. Br Dent J 2004;196:457-60.
  • Patil K, Mahima VG, Shetty SK, Lahari K. Facial plexiform neurofibroma in a child with neurofibromatosis type I: A case report. J Indian Soc Pedod Prev Dent 2007;25:30-5.
  • Stefano PC, Apa SN, Lanoël AM, María, JS, Sierre S, Pierini AM. Isolated plexiform neurofibroma mimicking a vascular lesion. An Bras Dermatol 2016;91:240-2.
  • Friedrich RE, Giese M, Schmelzle R, Mautner VF, Scheuer HA. Jaw malformations plus displacement and numerical aberrations of teeth in neurofibromatosis type 1: a descriptive analysis of 48 patients based on panoramic radiographs and oral findings. J Craniomaxillofac Surg 2003;31:1-9.
  • Cunha KS, Rozza-de-Menezes RE, Andrade RM, Almeida L, Janini M, Geller M. Oral manifestations of neurofibromatosis type 1 in children with facial plexiform neurofibroma: report of three cases. J Clin Pediatr Dent 2015;39:168-71.
  • Sigillo R, Rivera H, Nikitakis NG, Sauk JJ. Neurofibromatosis type 1: a clinicopathological study of the orofacial manifestations in 6 pediatric patients. Pediatr Dent 2002;24:575-80.
  • Fadda MT, Verdino G, Mustazza MC, Bartoli D, Iannetti G. Intra-parotid facial nerve multiple plexiform neurofibroma in patient with NF1. Int J Pediatr Otorhinolaryngol 2008;72:553-7.
  • McGuirt WF, Johnson PE, McGuirt WT. Intraparotid facial nerve neurofibromas. Laryngoscope 2003;113:82-4.
  • Waggoner DJ, Towbin J, Gottesman G, Gutmann DH. Clinic-based study of plexiform neurofibromas in neurofibromatosis 1. Am J Med Genet A 2000;92:132-5.
  • Bardellini E, Amadori F, Flocchini P, Conti G, Piana G, Majorana A. Oral findings in 50 children with neurofibromatosis type 1. A case control study. Eur J Paediatr Dent 2011;12:256-60.
  • O'Driscoll, PM. The oral manifestations of multiple neurofibromatosis. Br J Oral Surg 1965;3:22-31.
  • Friedrich RE, Giese M, Stelljes C, Froeder C, Scheuer HA. Size of tooth crowns and position of teeth concerning the extension of facial plexiform neurofibroma in patients with neurofibromatosis type 1. Anticancer Res 2012;32:2207-14.
There are 17 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Case Report
Authors

Buket Ceylan Çalık Yılmaz 0000-0003-4928-1352

Alev Alaçam

Publication Date January 2, 2019
Published in Issue Year 2019

Cite

APA Çalık Yılmaz, B. C., & Alaçam, A. (2019). Dental apseyi taklit eden bir patoloji: fasiyal pleksiform nörofibroma. Acta Odontologica Turcica, 36(1), 28-32. https://doi.org/10.17214/gaziaot.408607
AMA Çalık Yılmaz BC, Alaçam A. Dental apseyi taklit eden bir patoloji: fasiyal pleksiform nörofibroma. Acta Odontol Turc. January 2019;36(1):28-32. doi:10.17214/gaziaot.408607
Chicago Çalık Yılmaz, Buket Ceylan, and Alev Alaçam. “Dental Apseyi Taklit Eden Bir Patoloji: Fasiyal Pleksiform nörofibroma”. Acta Odontologica Turcica 36, no. 1 (January 2019): 28-32. https://doi.org/10.17214/gaziaot.408607.
EndNote Çalık Yılmaz BC, Alaçam A (January 1, 2019) Dental apseyi taklit eden bir patoloji: fasiyal pleksiform nörofibroma. Acta Odontologica Turcica 36 1 28–32.
IEEE B. C. Çalık Yılmaz and A. Alaçam, “Dental apseyi taklit eden bir patoloji: fasiyal pleksiform nörofibroma”, Acta Odontol Turc, vol. 36, no. 1, pp. 28–32, 2019, doi: 10.17214/gaziaot.408607.
ISNAD Çalık Yılmaz, Buket Ceylan - Alaçam, Alev. “Dental Apseyi Taklit Eden Bir Patoloji: Fasiyal Pleksiform nörofibroma”. Acta Odontologica Turcica 36/1 (January 2019), 28-32. https://doi.org/10.17214/gaziaot.408607.
JAMA Çalık Yılmaz BC, Alaçam A. Dental apseyi taklit eden bir patoloji: fasiyal pleksiform nörofibroma. Acta Odontol Turc. 2019;36:28–32.
MLA Çalık Yılmaz, Buket Ceylan and Alev Alaçam. “Dental Apseyi Taklit Eden Bir Patoloji: Fasiyal Pleksiform nörofibroma”. Acta Odontologica Turcica, vol. 36, no. 1, 2019, pp. 28-32, doi:10.17214/gaziaot.408607.
Vancouver Çalık Yılmaz BC, Alaçam A. Dental apseyi taklit eden bir patoloji: fasiyal pleksiform nörofibroma. Acta Odontol Turc. 2019;36(1):28-32.