BibTex RIS Cite

KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM

Year 2014, Volume: 29 Issue: 3, 0 - , 30.09.2014
https://doi.org/10.17341/gummfd.37710

Abstract

Günümüzde kullanılan otomatize kan kültür ölçüm yöntemlerinde genellikle floresanlı karbondioksitin ölçümüne dayanmaktadır. Bu yöntemin en büyük dezavantajı ölçüm süresinin uzun olması ve maliyet yüksekliğidir. Bu çalışmada, tarafımızdan geliştirilen ve kan kültüründeki üremeyi, kapalı bir tüp içerisindeki basınç değişiminin monitorizasyonuyla ölçen yeni bir kan kültürü sistemi sunulmuştur. Önerdiğimiz yeni yöntem daha hızlı ve daha ekonomiktir. Yaptığımız literatür taramasında benzer bir ölçüm metoduna ilişkin hiçbir araştırmaya İngilizce yayınlanmış araştırmaya ulaşamadık. Klasik kan kültürü tüplerini kullandığımız bu yöntemde, tüplerde oluşan basıncın anlık eğim değişiminin ölçülmesine dayanan ve klasik kan kültürü ölçüm tüplerinde bakteriyel üreme sırasında oluşan gazların basınç değişimini çok hassas ölçebilen ekonomik bir cihaz tasarlandı. Yapılan ölçümlerde önerdiğimiz yöntemle, mevcut otomatize sisteme göre, pozitif raporlama için yedi kat ve negatif raporlama için 10 kat daha hızlı sonuç verilebileceği saptandı. Bu yöntem sayesinde, daha ekonomik olan standart ölçüm tüpleri kullanılarak çok daha hızlı ve ekonomik şekilde ön değerlendirmeler yapılabilecektir.

References

  • Sehulster, L.M., Chinn, R.Y.W., Arduino, M.J., Carpenter, J., Donlan, R., Ashford, D., Besser, R., Fields, B., McNeil, M.M., Whitney, C., Wong, S., Juranek, D. ve Cleveland, J., “Guidelines for environmental infection control in health-care facilities”, Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee, Atlanta, A.B.D., 2003.
  • Craig, A., Umscheid, M.D., Rajender, K., Agarwal, M.D., Patrick, J. ve Brennan, M.D., “Guidelines for environmental infection control in health-care facilities”, Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee, Atlanta, A.B.D., 2009.
  • Weinstein, M.P., “Current blood culture methods and systems: clinical concepts, technology and interpretation of results”, Clinical Infectious Diseases, Cilt 23, No 1, 40-46, 1996.
  • Starnes, M.J., Brown, C.V., Morales, I.R., Hadjizacharia, P., Salim, A., Inaba, K., Rhee, P. ve Demetriades, D., “Evolving pathogens in the surgical intensive care unit: A 6-year experience”, Journal of Critical Care, Cilt 23, No 4, 507-512, 2008.
  • Paul, M., Kariv, G., Goldberg, E., Raskin, M., Shaked, H., Hazzan, R., Samra, Z., Paghis, D., Bishara, J. ve Leibovici, L., “Importance of appropriate empirical antibiotic therapy for methicillin-resistant Staphylococcus aureus bacteraemia”, Journal of Antimicrobial Chemotherapy, Cilt 65, No 2658–2665, 2010.
  • Diekema, D.J., Beekmann, S.E., Chapin, K.C., Morel, K.A., Munson, E. ve Doern, G.V., “Epidemiology and outcome of no-socomial and community-onset bloodstream infection”, Journal of Clinical Microbiology, Cilt 41, No 8, 3655-3660, 2003.
  • Barenfanger J., Graham D.R., Kolluri L., Sangwan G., Lawhorn J., Drake C.A., Verhulst S.J., Peterson R., Moja L.B., Ertmoed M.M., Moja A.B., Shevlin D.W., Vautrain R. ve Callahan C.D., “ Decreased mortality associated with prompt Gram staining of blood cultures”, American Journal of Clinical Pathology. Cilt 130, No 6, 870-876, 2008.
  • Makristathis, A., Riss, S. ve Hirschl, A.M., "A novel fluorescence in situ hybridization test for rapid pathogen identification in positive blood cultures", Clinical Microbiology and Infection, Basımda, 2014.
  • Martin, G.S., Mannino, D.M., Eaton, S. ve Moss, M., “The epidemiology of sepsis in the United States from 1979 through 2000”, The New England Journal Of Medicine, Cilt 348, No 16, 1546-1554, 2003.
  • Vincent, J.L., Sakr, Y., Sprung, C.L., Ranieri, V.M., Reinhart, K., Gerlach, H., Moreno, R., Carlet, J., Le Gall, J.R. ve Payen, D., “Sepsis in European intensive care units: results of the SOAP study”, Critical Care Medicine, Cilt 34, No 2, 344-353, 2006.
  • Bone, R.C., Balk, R.A., Cerra, F.B., Dellinger, R.P., Fein, A.M., Knaus, W.A., Schein, R.M. ve Sibbald, W.J., “Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis”, Chest Journal. Cilt 101, No 6, 1644-1655, 1992.
  • Murray, P.R., Traynor, P. ve Hopson, D., “Critical assessment of blood culture techniques: analysis of recovery of obligate and facultative anaerobes, strict aerobic bacteria, and fungi in aerobic and anaerobic blood culture bottles”, Journal of Clinical Microbiology, Cilt 30, No 6, 1462-1468, 1992.
  • Leea, D.H., Kimb, S.C., Baec, G., Koha, E.H., ve Kima, S., “Clinical Evaluation of BacT/Alert FA Plus and FN Plus Bottles Compared with Standard Bottles” Journal of Clinical Microbiology, Cilt 51, No 12, 4150-4155, 2013.
  • Deck, M.K., Anderson, E.S., Buckner, R.J., Colasante, G., Davis, T.E., Coull, J.M., Crystal, B., Latta, P.D., Fuchs, M., Fuller, D., Harris, W., Hazen, K., Klimas, L.L., Lindao, D., Meltzer, M.C., Morgan, M., Shepard, J., Stevens, S., Wu, F. ve Fiandaca, M.J., "Rapid detection of Enterococcus spp. direct from blood culture bottles using Enterococcus QuickFISH Method: a multicenter investigation", Diagnostic Microbiology and Infectious Disease, Cilt 78, No 4, 2014.
  • Yossepowitch, O., Dan, M., Kutchinsky, A., Gottesman, T. ve Schwartz-Harari O., "A cost-saving algorithm for rapid diagnosis of Staphylococcus aureus and susceptibility to oxacillin directly from positive blood culture bottles by combined testing with BinaxNOW® S. aureus and Xpert MRSA/SA assay", Diagnostic Microbiology and Infectious Disease, Cilt 78, No 4, 352-355, 2014.
  • Randa, K.H. ve Delanob, J.P., "Direct identification of bacteria in positive blood cultures: comparison of two rapid methods, FilmArray and mass spectrometry", Diagnostic Microbiology and Infectious Disease, Basımda, 2014.
  • Wanga, M.C., Linc, W.H., Yand, J.J., Fange, H.Y., Kuoa, T.H., Tsenga, C.C. ve Wuf, J.J., "Early identification of microorganisms in blood culture prior to the detection of a positive signal in the BACTEC FX system using matrix-assisted laser desorption/ionization–time of flight mass spectrometry", Journal of Microbiology, Immunology and Infection, Basımda, 2013.
  • Wojewoda, C.M., Sercia, L., Navas, M., Tuohy, M., Wilson, D., Hall, G.S., Procop, G.W. ve Richter, S,S., "Evaluation of the Verigene gram-positive blood culture nucleic acid test for rapid detection of bacteria and resistance determinants", Journal of Clinical Microbiology, Cilt 51, No 2072–2076, 2013.
  • Warke, N.V., Vaidya, P.P. ve Nair, J.M., "Exploring a new method for improving dynamic range of instrumentation amplifier for processing low voltage signals", IEEE 2013 International Conference on Emerging Trends in Communication, Control, Signal Processing & Computing Applications, Bangalore, Hindistan, 1-4, 10-11 Eylül 2013.
  • Srivastava, N., Shadab, A. ve Shukla, G., "Yokto (10-24V) Instrumentation Amplifier" IEEE 2012 Third International Conference on Computer and Communication Technology, Allahabad, Hindistan, 116-121, 23-25 Kasım 2012.
  • Salami, M.O., Alu, S.O., Opalekunde, A.B. ve Oladipo, O.A., “Comparative Analysis between Monophasic and Biphasic Methods of Blood Culture”, Journal of Biology, Agriculture and Healthcare, Cilt 2, No 4, 41-46, 2012.
  • Snyder, J.W. ve Lude, S.K., “Comparison of BacT/Alert FAN medium with Bactec NR660 plus 26A medium”, Journal of Clinical Microbiology, Cilt 34, No 5, 1327-1329. 1996.
  • Shoaei, S.D., Gachkarl, L., Rafizadeh, M.,Saphadel, N. ve Phaghani, Y.A., “Comparison of Mono and Biphasic Culture Media in Isolating Bacteria from Blood and evaluation Bu-Ali Hospital Lab Quality”, Journal of Paramedical Sciences, Cilt 2, No 1, 56-59, 2011.
  • Mirrett, S., Petti, C.A., Woods, C.W., Magadia, R., Weinstein, M.P. ve Reller, L.B., “Controlled clinical comparison of the BacT/ALERT FN and the standard anaerobic SN blood culturemedium”,Journal of Clinical Microbiology, Cilt 42, No 10, 4581-4585, 2004.
  • Shanson, D.C., “Blood culture technique: current controversies”, Journal of Antimicrobial Chemotherapy, Cilt 25, No Suppl C, 17-29, 1990.
  • Weckbach, L.S. ve Staneck, J.L., “Performance Characteristics of a Commercially Prepared Biphasic Blood Culture Bottle”, Journal of Clinical Microbiology, Cilt 23, No 4, 700-703, 1986.
Year 2014, Volume: 29 Issue: 3, 0 - , 30.09.2014
https://doi.org/10.17341/gummfd.37710

Abstract

References

  • Sehulster, L.M., Chinn, R.Y.W., Arduino, M.J., Carpenter, J., Donlan, R., Ashford, D., Besser, R., Fields, B., McNeil, M.M., Whitney, C., Wong, S., Juranek, D. ve Cleveland, J., “Guidelines for environmental infection control in health-care facilities”, Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee, Atlanta, A.B.D., 2003.
  • Craig, A., Umscheid, M.D., Rajender, K., Agarwal, M.D., Patrick, J. ve Brennan, M.D., “Guidelines for environmental infection control in health-care facilities”, Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee, Atlanta, A.B.D., 2009.
  • Weinstein, M.P., “Current blood culture methods and systems: clinical concepts, technology and interpretation of results”, Clinical Infectious Diseases, Cilt 23, No 1, 40-46, 1996.
  • Starnes, M.J., Brown, C.V., Morales, I.R., Hadjizacharia, P., Salim, A., Inaba, K., Rhee, P. ve Demetriades, D., “Evolving pathogens in the surgical intensive care unit: A 6-year experience”, Journal of Critical Care, Cilt 23, No 4, 507-512, 2008.
  • Paul, M., Kariv, G., Goldberg, E., Raskin, M., Shaked, H., Hazzan, R., Samra, Z., Paghis, D., Bishara, J. ve Leibovici, L., “Importance of appropriate empirical antibiotic therapy for methicillin-resistant Staphylococcus aureus bacteraemia”, Journal of Antimicrobial Chemotherapy, Cilt 65, No 2658–2665, 2010.
  • Diekema, D.J., Beekmann, S.E., Chapin, K.C., Morel, K.A., Munson, E. ve Doern, G.V., “Epidemiology and outcome of no-socomial and community-onset bloodstream infection”, Journal of Clinical Microbiology, Cilt 41, No 8, 3655-3660, 2003.
  • Barenfanger J., Graham D.R., Kolluri L., Sangwan G., Lawhorn J., Drake C.A., Verhulst S.J., Peterson R., Moja L.B., Ertmoed M.M., Moja A.B., Shevlin D.W., Vautrain R. ve Callahan C.D., “ Decreased mortality associated with prompt Gram staining of blood cultures”, American Journal of Clinical Pathology. Cilt 130, No 6, 870-876, 2008.
  • Makristathis, A., Riss, S. ve Hirschl, A.M., "A novel fluorescence in situ hybridization test for rapid pathogen identification in positive blood cultures", Clinical Microbiology and Infection, Basımda, 2014.
  • Martin, G.S., Mannino, D.M., Eaton, S. ve Moss, M., “The epidemiology of sepsis in the United States from 1979 through 2000”, The New England Journal Of Medicine, Cilt 348, No 16, 1546-1554, 2003.
  • Vincent, J.L., Sakr, Y., Sprung, C.L., Ranieri, V.M., Reinhart, K., Gerlach, H., Moreno, R., Carlet, J., Le Gall, J.R. ve Payen, D., “Sepsis in European intensive care units: results of the SOAP study”, Critical Care Medicine, Cilt 34, No 2, 344-353, 2006.
  • Bone, R.C., Balk, R.A., Cerra, F.B., Dellinger, R.P., Fein, A.M., Knaus, W.A., Schein, R.M. ve Sibbald, W.J., “Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis”, Chest Journal. Cilt 101, No 6, 1644-1655, 1992.
  • Murray, P.R., Traynor, P. ve Hopson, D., “Critical assessment of blood culture techniques: analysis of recovery of obligate and facultative anaerobes, strict aerobic bacteria, and fungi in aerobic and anaerobic blood culture bottles”, Journal of Clinical Microbiology, Cilt 30, No 6, 1462-1468, 1992.
  • Leea, D.H., Kimb, S.C., Baec, G., Koha, E.H., ve Kima, S., “Clinical Evaluation of BacT/Alert FA Plus and FN Plus Bottles Compared with Standard Bottles” Journal of Clinical Microbiology, Cilt 51, No 12, 4150-4155, 2013.
  • Deck, M.K., Anderson, E.S., Buckner, R.J., Colasante, G., Davis, T.E., Coull, J.M., Crystal, B., Latta, P.D., Fuchs, M., Fuller, D., Harris, W., Hazen, K., Klimas, L.L., Lindao, D., Meltzer, M.C., Morgan, M., Shepard, J., Stevens, S., Wu, F. ve Fiandaca, M.J., "Rapid detection of Enterococcus spp. direct from blood culture bottles using Enterococcus QuickFISH Method: a multicenter investigation", Diagnostic Microbiology and Infectious Disease, Cilt 78, No 4, 2014.
  • Yossepowitch, O., Dan, M., Kutchinsky, A., Gottesman, T. ve Schwartz-Harari O., "A cost-saving algorithm for rapid diagnosis of Staphylococcus aureus and susceptibility to oxacillin directly from positive blood culture bottles by combined testing with BinaxNOW® S. aureus and Xpert MRSA/SA assay", Diagnostic Microbiology and Infectious Disease, Cilt 78, No 4, 352-355, 2014.
  • Randa, K.H. ve Delanob, J.P., "Direct identification of bacteria in positive blood cultures: comparison of two rapid methods, FilmArray and mass spectrometry", Diagnostic Microbiology and Infectious Disease, Basımda, 2014.
  • Wanga, M.C., Linc, W.H., Yand, J.J., Fange, H.Y., Kuoa, T.H., Tsenga, C.C. ve Wuf, J.J., "Early identification of microorganisms in blood culture prior to the detection of a positive signal in the BACTEC FX system using matrix-assisted laser desorption/ionization–time of flight mass spectrometry", Journal of Microbiology, Immunology and Infection, Basımda, 2013.
  • Wojewoda, C.M., Sercia, L., Navas, M., Tuohy, M., Wilson, D., Hall, G.S., Procop, G.W. ve Richter, S,S., "Evaluation of the Verigene gram-positive blood culture nucleic acid test for rapid detection of bacteria and resistance determinants", Journal of Clinical Microbiology, Cilt 51, No 2072–2076, 2013.
  • Warke, N.V., Vaidya, P.P. ve Nair, J.M., "Exploring a new method for improving dynamic range of instrumentation amplifier for processing low voltage signals", IEEE 2013 International Conference on Emerging Trends in Communication, Control, Signal Processing & Computing Applications, Bangalore, Hindistan, 1-4, 10-11 Eylül 2013.
  • Srivastava, N., Shadab, A. ve Shukla, G., "Yokto (10-24V) Instrumentation Amplifier" IEEE 2012 Third International Conference on Computer and Communication Technology, Allahabad, Hindistan, 116-121, 23-25 Kasım 2012.
  • Salami, M.O., Alu, S.O., Opalekunde, A.B. ve Oladipo, O.A., “Comparative Analysis between Monophasic and Biphasic Methods of Blood Culture”, Journal of Biology, Agriculture and Healthcare, Cilt 2, No 4, 41-46, 2012.
  • Snyder, J.W. ve Lude, S.K., “Comparison of BacT/Alert FAN medium with Bactec NR660 plus 26A medium”, Journal of Clinical Microbiology, Cilt 34, No 5, 1327-1329. 1996.
  • Shoaei, S.D., Gachkarl, L., Rafizadeh, M.,Saphadel, N. ve Phaghani, Y.A., “Comparison of Mono and Biphasic Culture Media in Isolating Bacteria from Blood and evaluation Bu-Ali Hospital Lab Quality”, Journal of Paramedical Sciences, Cilt 2, No 1, 56-59, 2011.
  • Mirrett, S., Petti, C.A., Woods, C.W., Magadia, R., Weinstein, M.P. ve Reller, L.B., “Controlled clinical comparison of the BacT/ALERT FN and the standard anaerobic SN blood culturemedium”,Journal of Clinical Microbiology, Cilt 42, No 10, 4581-4585, 2004.
  • Shanson, D.C., “Blood culture technique: current controversies”, Journal of Antimicrobial Chemotherapy, Cilt 25, No Suppl C, 17-29, 1990.
  • Weckbach, L.S. ve Staneck, J.L., “Performance Characteristics of a Commercially Prepared Biphasic Blood Culture Bottle”, Journal of Clinical Microbiology, Cilt 23, No 4, 700-703, 1986.
There are 26 citations in total.

Details

Primary Language Turkish
Journal Section Makaleler
Authors

Gürsel Düzenli

Oğuz Karabay

Publication Date September 30, 2014
Submission Date September 30, 2014
Published in Issue Year 2014 Volume: 29 Issue: 3

Cite

APA Düzenli, G., & Karabay, O. (2014). KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi, 29(3). https://doi.org/10.17341/gummfd.37710
AMA Düzenli G, Karabay O. KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM. GUMMFD. September 2014;29(3). doi:10.17341/gummfd.37710
Chicago Düzenli, Gürsel, and Oğuz Karabay. “KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM”. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi 29, no. 3 (September 2014). https://doi.org/10.17341/gummfd.37710.
EndNote Düzenli G, Karabay O (September 1, 2014) KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi 29 3
IEEE G. Düzenli and O. Karabay, “KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM”, GUMMFD, vol. 29, no. 3, 2014, doi: 10.17341/gummfd.37710.
ISNAD Düzenli, Gürsel - Karabay, Oğuz. “KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM”. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi 29/3 (September 2014). https://doi.org/10.17341/gummfd.37710.
JAMA Düzenli G, Karabay O. KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM. GUMMFD. 2014;29. doi:10.17341/gummfd.37710.
MLA Düzenli, Gürsel and Oğuz Karabay. “KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM”. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi, vol. 29, no. 3, 2014, doi:10.17341/gummfd.37710.
Vancouver Düzenli G, Karabay O. KAN KÜLTÜRLERİN DÜŞÜK MALİYETLİ VE HIZLI ÖLÇÜLEBİLMESİ İÇİN YENİ BİR YAKLAŞIM. GUMMFD. 2014;29(3).