Farklı Cihazlarda İyon Seçici Elektrot (ISE) Yöntemi ile Ölçülen Sodyum, Potasyum ve Klor Sonuçlarının Kıyaslanması

Year 2022, , 198 - 202, 29.04.2022

Turan Akdağ , Saadet Kader , Hüseyin Dost , Ali Ünlü

https://doi.org/10.54005/geneltip.1038123

Abstract

Amaç: Elektrolit ölçümleri, klinik biyokimya laboratuvarlarında yapılan rutin testlerin vazgeçilmez bir parçasıdır. Bu çalışmada, serum sodyum (Na), potasyum (K) ve klor (Cl) elektrolitleri iyon seçici elektrot (ISE) yöntemi ile ölçülmüş ve doğrusallık, kesinlik, tekrarlanabilirlik ve doğruluk seviyeleri Mindray BS-800M ve Beckman Coulter AU5800 cihazlarında değerlendirilmesi amaçlanmaktadır.
Gereç ve yöntem: Serum örnekleri, Ocak-Nisan 2021 tarihleri arasında Karapınar Devlet Hastanesi'ne kontrol amaçlı başvuran sağlıklı gönüllülerden alınmıştır. Örnek probu, ISE yöntemi için ayrı bir numune probu olup Mindray BS-800M ve Beckman Coulter AU5800 cihazlarında indirekt yöntem kullanılarak gerçekleştirilmiştir.
Bulgular: Karşılaştırmalı ölçümler farklı cihazlarda yapılırken elektrolitler arasındaki korelasyonlar Na [r=0,964, % 95 CI (0,52-0,90)], K [r=0,995, % 95 CI (0,09-) 0.12)] ve Cl [r=0.972, % 95 CI (0.69-1.12)] olarak bulundu. Ayrıca bu sonuçlar arasında da bir korelasyon belirlenmiştir.
Sonuç: Farklı analizörlerde ölçülen Na, K ve Cl elektrolitleri arasında bir tutarlılık belirlendi. Ayrıca, bu elektrolitler arasında pozitif bir korelasyon bulunmaktadır. Bu sonuçların açıklığa kavuşturulması için daha fazla ve kapsamlı çalışmalara ihtiyaç olduğu görülmektedir.

Keywords

Klor, elektrolit, potasyum, sodyum

Supporting Institution

Yok

Project Number

-

Comparison of the Results of Sodium, Potassium, and Chlorine Measured Through Ion Selective Electrode (ISE) Method in Different Devices

Abstract

Objective: The measurements of electrolytes are an indispensable part of the routine tests performed in clinical biochemistry laboratories. In the present study, we aimed to measure serum sodium (Na), potassium (K), and chlorine (Cl) electrolytes via the ion-selective electrode (ISE) method and evaluated in terms of linearity, precision, repeatability, and accuracy levels in the Mindray BS-800M and Beckman Coulter AU5800 devices.
Material and methods: The serum samples were obtained from the healthy volunteers admitted to the Karapınar State Hospital for control purposes between January and April 2021. The sample probe was conducted using the same indirect method in the Mindray BS-800M and Beckman Coulter AU5800 devices, which is an individual sample probe for the ISE method.
Results: While the comparative measurements were performed on different devices, the correlations between the electrolytes were found as follows: Na [r=0.964, 95% CI (0.52-0.90)], K [r=0.995, 95% CI (0.09-0.12)], and Cl [r=0.972, 95% CI (0.69-1.12)]. Moreover, a correlation was also found between these results.
Conclusion: A consistency between the measured Na, K, and Cl electrolytes was determined on the different analyzers. Also, a positive correlation was determined between those electrolytes. We consider that further and comprehensive studies are needed to elucidate these results.

Keywords

Chlorine, electrolyte, potassium, sodium

Project Number

-

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