Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi

Burak Tan; Ercan Babur; Hikmet Fırat Örnek; Cem Süer; Nurcan Dursun

TR EN

Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi

Abstract

Amaç: Gelişimsel dönemdeki hipotiroidi ve hipertiroidi gibi tiroid hormon seviyesi bozukluklarında, beyinde yapısal ve fonksiyonel değişikliklerin olduğu deneysel çalışmalarda gösterilmiştir. Bu değişikliklerin, hipokampüsün önemli rol oynadığı öğrenme ve bellek gibi bilişsel süreçlerde bozulmalara ve nörolojik bozukluklara neden olduğu bilinmektedir. Bu amaçla hipertiroidili erkek ve dişi sıçanlar arasında uzamsal öğrenme performansının araştırılması amaçlanmıştır. Gereç ve Yöntem: Hipertiroidi oluşturmak için erkek ve dişi sıçanlara 21 gün süreyle 0,2 mg/kg dozda L-Tiroksin İp olarak uygulanmıştır. Öğrenme ve bellek performansını değerlendirmek için Morris su tankı testi MST kullanılmıştır. Bulgular: Tekrarlayan ölçümlerle ANOVA testi yapıldığında cinsiyet faktörü platforma olan ortalama uzaklığı anlamlı p

Keywords

Hipertiroidizm, öğrenme ve bellek, hipokampüs, morris su tankı

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Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Burak Tan This is me

Ercan Babur

Hikmet Fırat Örnek

Cem Süer This is me

Nurcan Dursun This is me

Publication Date

March 1, 2018

Submission Date

-

Acceptance Date

-

Published in Issue

Year 2018 Volume: 28 Number: 2

IZ

https://izlik.org/JA65XJ48LC

APA

Tan, B., Babur, E., Örnek, H. F., Süer, C., & Dursun, N. (2018). Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi. Genel Tıp Dergisi, 28(2), 69-75. https://izlik.org/JA65XJ48LC

AMA

1.Tan B, Babur E, Örnek HF, Süer C, Dursun N. Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi. Genel Tıp Derg. 2018;28(2):69-75. https://izlik.org/JA65XJ48LC

Chicago

Tan, Burak, Ercan Babur, Hikmet Fırat Örnek, Cem Süer, and Nurcan Dursun. 2018. “Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi”. Genel Tıp Dergisi 28 (2): 69-75. https://izlik.org/JA65XJ48LC.

EndNote

Tan B, Babur E, Örnek HF, Süer C, Dursun N (March 1, 2018) Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi. Genel Tıp Dergisi 28 2 69–75.

IEEE

[1]B. Tan, E. Babur, H. F. Örnek, C. Süer, and N. Dursun, “Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi”, Genel Tıp Derg, vol. 28, no. 2, pp. 69–75, Mar. 2018, [Online]. Available: https://izlik.org/JA65XJ48LC

ISNAD

Tan, Burak - Babur, Ercan - Örnek, Hikmet Fırat - Süer, Cem - Dursun, Nurcan. “Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi”. Genel Tıp Dergisi 28/2 (March 1, 2018): 69-75. https://izlik.org/JA65XJ48LC.

JAMA

1.Tan B, Babur E, Örnek HF, Süer C, Dursun N. Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi. Genel Tıp Derg. 2018;28:69–75.

MLA

Tan, Burak, et al. “Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi”. Genel Tıp Dergisi, vol. 28, no. 2, Mar. 2018, pp. 69-75, https://izlik.org/JA65XJ48LC.

Vancouver

1.Burak Tan, Ercan Babur, Hikmet Fırat Örnek, Cem Süer, Nurcan Dursun. Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi. Genel Tıp Derg [Internet]. 2018 Mar. 1;28(2):69-75. Available from: https://izlik.org/JA65XJ48LC

The Journal of General Medicine is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY NC).

Hipertiroidili Sıçanlarda Uzamsal Öğrenme Performansına Cinsiyetin Etkisi

Abstract

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References

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