The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia

Year 2024, , 616 - 623, 31.10.2024

Tuba Şahinoğlu

https://doi.org/10.54005/geneltip.1411168

Abstract

Background: Pneumothorax and lymphopenia regarded as poor prognostic factors in covid-19 pneumonia.In this study, we aimed to determine whether there is a relationship between pneumothorax and lymphopenia in patients admitted to the intensive care unit due to COVID-19 pneumonia and evaluate whether lymphocyte count can be used to predict the development of pneumothorax.
Methods: We reviewed the records of 50 patients with COVID-19 pneumonia retrospectively who developed pneumothorax and underwent tube thoracostomy at our hospital's intesive care units
Results : There were 32 women and 18 men with a mean age of 67.98 years.Of the patients who developed pneumothorax, 78% were intubated. 86% of the patients with pneumothorax died.The risk of mortality in patients with pneumothorax decreased 0.198 times as lymphocyte count increased. In ROC curve analysis based on intubation status, a cut-off value of 1.02 for lymphocyte count is statistically significant.
Conclusions: In this study, we observed that intubated patients had a high likelihood of developing pneumothorax and that concomitant deep lymphopenia was directly associated with mortality. The results highlight that during intensive care follow-up, it must be kept in mind that poor prognostic factors can interact to result in more serious prognostic implications

Keywords

Covid-19, intensive care unit, lymphopenia, pneumothorax

Covid-19 Pnömonisi Olan Hastalarda Pnömotoraks ve Lenfopeni Arasındaki İlişki

Abstract

Giriş: Pnömotoraks ve lenfopeni, covid-19 pnömonisinde kötü prognostik faktörler olarak kabul edilmektedir. Bu çalışmada, COVID-19 pnömonisi nedeniyle yoğun bakım ünitesine başvuran hastalarda pnömotoraks ve lenfopeni arasında bir ilişki olup olmadığını belirlemeyi ve lenfosit sayımının pnömotoraks gelişimini tahmin etmede kullanılıp kullanılamayacağını değerlendirmeyi amaçladık.
Method: Hastanemiz yoğun bakım ünitelerinde pnömotoraks gelişen ve tüp torakostomi uygulanan COVID-19 pnömonisi gelişen 50 hastasının kayıtlarını retrospektif olarak inceledik.
Bulgular: Yaş ortalaması 67.98 olan 32 kadın ve 18 erkek vardı. Pnömotoraks gelişen hastaların %78' i entübe edildi. Pnömotorakslı hastaların %86' sı öldü. Lenfosit sayısı arttıkça pnömotorakslı hastalarda ölüm riski 0,198 kat azaldı. Entübasyon durumuna dayalı ROC eğrisi analizinde, lenfosit sayısı için 1,02' lik bir cut-off değeri istatistiksel olarak anlamlı geldi.
Sonuçlar: Bu çalışmada entübe hastalarda pnömotoraks gelişme olasılığının yüksek olduğunu ve eşlik eden derin lenfopeninin mortalite ile doğrudan ilişkili olduğunu gözlemledik. Sonuçlar, yoğun bakım takibi sırasında, kötü prognostik faktörlerin etkileşime girerek daha ciddi prognostik sonuçlara yol açabileceğinin akılda tutulması gerektiğini vurgulamaktadır.

Keywords

Kovid-19, lenfopeni, pnömotoraks, yoğun bakım

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