Review

Overview of Cryptosporidium spp.

Volume: 35 Number: 1 February 28, 2025
EN

Overview of Cryptosporidium spp.

Abstract

Abstract Cryptosporidium spp., the causative agent of Cryptosporidiosis, is an obligate intracellular and extracytoplasmic protozoan. Cryptosporidium spp., emerges as a public health problem transmitted by contaminated water and food due to its features such as the widespread occurrence of oocysts in nature, low infective doses, ability to pass through the filters of treatment plants, resistance to disinfectants, and ability to survive in water and soil for months at appropriate humidity and temperature. Transmission to humans usually occurs through the fecal-oral route by ingestion of oocysts. However, endogenous auto-infection can ocur. Respiratory transmission has been reported. Cryptosporidium spp. infections may lead to serious life-threatening clinical conditions in children under two years of age and immunosuppressed patients. In order to prevent water and foodborne cryptosporidiosis outbreaks and protect public health, the causes of Cryptosporidium oocysts contaminating these resources should be determined, necessary precautions should be taken and combat methods should be determined. In this review, information on the life cycle, epidemiology, clinical findings, diagnosis, protection, and control of Cryptosporidium spp. is presented.

Keywords

cryptosporidium, protozoan, immunosuppressive

References

  1. 1. Laksemi DA, Suwanti LT, Mufasirin M, Suastika K, Sudarmaja M. Opportunistic Parasitic Infections in Patients with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome: A Review. Vet World 2019; 13(4): 716-25.
  2. 2. Leder K, Weller PF. Epidemiology, clinical manifestations, and diagnosis of cryptosporidiosis. Available from:URL:https://www.uptodate.com/contents/epidemiology-clinical-manifestations-and-diagnosis-ofcryptosporidiosis.
  3. 3. Yalçın S, Doğan NY. Determination of Cryptosporidium spp by Molecular Methods in Different Water Resources of Erzincan Province. Erzincan University Journal of Science and Technology 2019; 12(1): 1-13.
  4. 4. Wang P, Li S, Zou Y, Du ZC, Song DP, Wang P, et al. The Infection and Molecular Characterization of Cryptosporidium spp. in Diarrheic Pigs in Southern China. Microb Pathog 2022; 165: 105459.
  5. 5. Şahin S, Ağaoğlu S, Alemdar S. Cryptosporidium ve Cryptosporidiosis. Türkiye Klinikleri; 2018; 35-41.
  6. 6. Ulusan Bağcı Ö, Caner A. miRNA Expression Profile in Ileocecal Adenocarcinoma Cells Infected with Cryptosporidium. Mikrobiyol Bul 2022; 56(3): 449-465.
  7. 7. Aksoy Ü. Bioterorism, Prasites as Potential Bioterrorism Agents and Biosecurity studies. Mikrobiyol Bul 2006; 40: 129-139.
  8. 8. Fayer R. General biology. In: Fayer R, Xiao L. eds. Cryptospsoridium and Cryptosporidiosis. Boca Raton: CRC Press; 2008; 1-42.
  9. 9. Chalmers RM, Davies AP. Clinical cryptosporidiosis. Exp Parasitol 2010; 124(1): 138- 46.
  10. 10. Caccio SM, Putignani L. Epidemiology of Human Cryptosporidiosis. In: Caccio S, Widmer G, eds. Cryptosporidium: parasite and disease. Vienna: Springer; 2014; 43-79.
APA
Beder, D. (2025). Overview of Cryptosporidium spp. Genel Tıp Dergisi, 35(1), 212-218. https://doi.org/10.54005/geneltip.1469783
AMA
1.Beder D. Overview of Cryptosporidium spp. Genel Tıp Derg. 2025;35(1):212-218. doi:10.54005/geneltip.1469783
Chicago
Beder, Duygu. 2025. “Overview of Cryptosporidium Spp”. Genel Tıp Dergisi 35 (1): 212-18. https://doi.org/10.54005/geneltip.1469783.
EndNote
Beder D (February 1, 2025) Overview of Cryptosporidium spp. Genel Tıp Dergisi 35 1 212–218.
IEEE
[1]D. Beder, “Overview of Cryptosporidium spp”., Genel Tıp Derg, vol. 35, no. 1, pp. 212–218, Feb. 2025, doi: 10.54005/geneltip.1469783.
ISNAD
Beder, Duygu. “Overview of Cryptosporidium Spp”. Genel Tıp Dergisi 35/1 (February 1, 2025): 212-218. https://doi.org/10.54005/geneltip.1469783.
JAMA
1.Beder D. Overview of Cryptosporidium spp. Genel Tıp Derg. 2025;35:212–218.
MLA
Beder, Duygu. “Overview of Cryptosporidium Spp”. Genel Tıp Dergisi, vol. 35, no. 1, Feb. 2025, pp. 212-8, doi:10.54005/geneltip.1469783.
Vancouver
1.Duygu Beder. Overview of Cryptosporidium spp. Genel Tıp Derg. 2025 Feb. 1;35(1):212-8. doi:10.54005/geneltip.1469783