Automatic Segmentation of the Cerebellum in Healthy Individuals: A volBrain (CERES) Study
Abstract
ABSTRACT
Aim: We aimed to investigate the total cerebellum volume and the volume of healthy individuals' right and left cerebellum lobes according to age groups and sex.
Methods: 3T T1-weighted Magnetic Resonance Images of 200 individuals (100 female, 100 male) of both sexes between the ages of 18-78 were included in our study. Total cerebellum volume and volume results of cerebellum lobules will be calculated from these images with the sub-tab CERES of the volBrain software program.
Results: The total cerebellum volume in our study was found to be 115.41±12.25 cm3 in females and 126.27±14.78 cm3 in males, and the values were statistically significant (p<0.001). The right side lobule I-II, lobule IV, lobule crus II, lobule VIIB, lobule VIIIA and lobule X values of the cerebellum were statistically higher than the left side (p<0.05). On the left side, lobule V, VIIIB and IX values were statistically higher than the right side (p<0.05). When evaluated according to sex, the values of males were statistically higher than females in all parameters except for the total lobule I-II, right lobule I-II, left lobule I-II, right lobule V, total lobule VI and right lobule VI values (p<0.05). According to age groups, except for total lobule I-II, right lobule I-II and left lobule I-II values, all other parameters were statistically lower in the 50-year-old and above group than in the under-50-year-old group (p<0.05).
Conclusion: We believe that knowing the total cerebellum volume and volumetric analysis of its lobules in healthy adults will define the disease group and its prognosis.
Keywords
Age, Cerebellum, Magnetic Resonance Imaging, Sex, volBrain, Volume
Ethical Statement
Approval was received from the Ankara Etlik City Hospital Scientific Research Evaluation and Ethics Committee with the decision number AEŞH-BADEK-2024-770.
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