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Akciğer Bilgisayarlı Tomografisinde Sık Görülen Mozaik Perfüzyon Etyolojisinde Radyolojik İpuçları

Year 2020, Volume: 30 Issue: 4, 218 - 223, 01.12.2020

Abstract

Amaç: Bu çalışmamızda günlük radyoloji pratiğinde akciğer bilgisayarlı tomografide BT sık karşılaştığımız mozaik atenuasyon MA paterni olan hastalarda altta yatan süreci tanımlamaya yönelik, görüntüleme bulgularının radyolojik ipuçlarını literatür eşliğinde sunmayı amaçladık.Gereç ve Yöntem: MA paterni olan 400 hastanın toraks BT’si retrospektif olarak incelendi. Görece lüsen alanların mı mozaik perfüzyon ; yoksa görece opak alanların mı buzlu cam anormal olduğunu belirlemek için öncelikle damar çaplarına bakıldı. Damar çapı lüsen alanda daha küçük ise bu alan patolojik kabul edildi. Sonra mozaik perfüzyon nedenleri vasküler mi küçük hava yolu hastalığı mı diye direkt ve indirekt bulgulara bakıldı. Mozaik perfüzyonun havayolu hastalığı bulgularından bronş duvarı kalınlaşması, tomurcuklanmış ağaç görünümü ve bronşektazi direk; santral yerleşim, lobüler görünüm, küçük ve keskin kenarlı lüsen alanlar ise indirekt bulgular olarak kabul edildi. Vasküler nedenli MA’nun direk bulguları trombüs ve pulmoner arter genişlemesi iken periferal yerleşim, daha büyük ve sınırları net olmayan lüsen alanlar ise indirek bulgular olarak kabul edildi. Daha sonra bulgular klinik sonuçlar ile de korele edildi.Bulgular: MA’nın nedeni 190 %47.5 hastada buzlu cam olarak tespit edildi. Lüsen alanların patolojik olduğu 210 hastanın 140’ı %67 küçük hava yolu ve 70’i %33 vasküler nedenli idi. Hava yolu hastalığına bağlı mozaik perfüzyon olan hastalarda toraks BT’de en sık tomurcuklanmış ağaç, bronş duvarında kalınlaşma ve bronşektazi izlendi. Vasküler hastalığa bağlı mozaik perfüzyonda ise kronik pulmoner emboli ve pulmoner hipertansiyon bulguları eşlik etmekteydiSonuç: Mozaik atenuasyon paterni düşünüldüğü kadar nonspesifik bir bulgu olmayıp radyologlar tarafından sistematik bir yaklaşım ile BT bulguları değerlendirilerek ayırıcı tanıya ve tedaviye katkı sunulabilir

References

  • Hansell D M, Bankier AA, MacMahon H, McLoud TC, Muller NL, Remy J. FleischnerSociety: glossary of terms- forthoracicimaging. Radiology 2008; 246: 697-722.
  • Ridge CA, Bankier AA, Eisenberg RL. Mosaicattenuation. AJR Am J Roentgenol 2011;197, 970–7.
  • Stern EJ, Muller NL, Swensen SJ, Hartman TE. CT mosai- cpattern of lung attenuation: Etiologies and terminology. J Thorac Imaging 1995; 10: 294–7.
  • Stern EJ, Swensen SJ, Hartman TE, Frank MS. CT mosaic pattern of lung attenuation: Distinguishing different causes. AJR Am J Roentgenol 1995; 165: 813–6.
  • Sherrick AD, Swensen SJ, Hartman TE. Mosaic pattern of lungattenuation on CT scans: Frequency among patients with pulmonary artery thy pertension of differentcauses. AJR Am J Roentgenol 1997; 169: 79–82.
  • Worthy SA, Muller NL, Hartman TE, Swensen SJ, Padley SP, Hansell DM. Mosaic attenuation pattern on thin-section CT scans of thelung: Differentiation among infiltrative lun- g,airway, and vascular diseases as a cause. Radiology 1997; 205: 465–70.
  • Elicker BM, Webb WR. Yüksek Çözünürlüklü Akciğer BT-Temeller: Sık Karşılaşılan Bulgular, Paternler, Hastalık- lar ve Ayırıcı Tanı, çev: Çetin Atasoy, Dünya tıp kitapevi 2015; 75-7.
  • Remy-Jardin M, Remy J, Giraud F, WattineL, Gosselin B. Computed tomography assessment of ground-glass opa- city: semiology and significance. J Thorac Imaging 1993; 8:249-64.
  • Stern EJ, Webb WR. Dynamic imaging of lung morpho- logy with ultrafast high-resolution computed tomography. J ThoracImaging 1993:8:273-82.
  • Webb WR, Stern EJ, Kanth N, Gamsu G. Dynamic pul- monary CT: findings in healthy adult men. Radiology 1993:186:117-24.
  • Kligerman SJ, Henry T, Lin CT, Franks TJ, Galvin JR. Mo- saic attenuation: etiology, methods of differentiation, and pitfalls. Radiographics 2015;35(5): 1360-80.
  • Gotway MB, Reddy GP, Webb WR, Elicker BM, LeungJ W. High-resolution CT of thelung: patterns of disease and dif- ferential diagnoses. Radiol Clin North Am 2005;43:513-22.
  • Ng CS, Wells AU, Padley SP. A CT sign of chronic pulmo- nary arterial hypertension: the ratio of main pulmonary artery to aortic diameter. J Thorac Imaging 1999;14:270–8.
  • Devaraj A, Wells AU, Meister MG, Corte TJ, Wort SJ, Han- sellDM. Detection of pulmonary hypertension with multi- detector CT and echocardiography alone and in combinati- on Radiology 2010;254:609–16.
  • Tan RT, Kuzo R, Goodman LR, Siegel R, Haasler GB,Pres- berg KW. Utility of CT scan evaluation for predicting pul- monary hypertension in patients with parenchymal lung disease. Medical College of Wisconsin Lung Transplant Group. Chest 1998;113:1250–6.

Radiological clues in etıology of mosaic perfusion that is frequently seen in lung computed tomography

Year 2020, Volume: 30 Issue: 4, 218 - 223, 01.12.2020

Abstract

Objective: We aimed to present the radiological clues of computed tomography CT imaging findings of patients with mosaic attenuation MA pattern.Material and Methods: Thoracic CT images of 400 patients with MA pattern were retrospectively reviewed. First of all, we looked at vessel diameters to determine whether relative lucent areas mosaic perfusion or relative opaque areas ground glass opacity were pathological.If the vessel diameter was smaller in the lucent area, this area was considered pathological. Then, the direct and indirect findings were investigated whether the cause of mosaic perfusion was vascular disease or small airway disease. Bronchial wall thickening, tree-in-bud appearance and bronchiectasis were the direct signs of mosaic perfusion; central location, lobular appearance, small and sharp-edged lucent areas were accepted as indirect findings. The direct findings of MA due to vascular disease were thrombus and enlarged pulmonary artery; peripheral location, larger and unclear lucent areas were accepted as indirect findings. The findings were then correlated with clinical outcomes.Results: The cause of mosaic attenuation was found to be ground glass in 190 47.5% patients. Of the 210 patients whose lucent areas were pathological, 140 67% were caused by small airway disease and 70 33% were caused by vascular diseaseConclusion: The mosaic attenuation pattern is not as nonspecific as it is thought, and radiologic evaluation of computerized tomography findings by a systematic approach may contribute to differential diagnosis and clinical treatment

References

  • Hansell D M, Bankier AA, MacMahon H, McLoud TC, Muller NL, Remy J. FleischnerSociety: glossary of terms- forthoracicimaging. Radiology 2008; 246: 697-722.
  • Ridge CA, Bankier AA, Eisenberg RL. Mosaicattenuation. AJR Am J Roentgenol 2011;197, 970–7.
  • Stern EJ, Muller NL, Swensen SJ, Hartman TE. CT mosai- cpattern of lung attenuation: Etiologies and terminology. J Thorac Imaging 1995; 10: 294–7.
  • Stern EJ, Swensen SJ, Hartman TE, Frank MS. CT mosaic pattern of lung attenuation: Distinguishing different causes. AJR Am J Roentgenol 1995; 165: 813–6.
  • Sherrick AD, Swensen SJ, Hartman TE. Mosaic pattern of lungattenuation on CT scans: Frequency among patients with pulmonary artery thy pertension of differentcauses. AJR Am J Roentgenol 1997; 169: 79–82.
  • Worthy SA, Muller NL, Hartman TE, Swensen SJ, Padley SP, Hansell DM. Mosaic attenuation pattern on thin-section CT scans of thelung: Differentiation among infiltrative lun- g,airway, and vascular diseases as a cause. Radiology 1997; 205: 465–70.
  • Elicker BM, Webb WR. Yüksek Çözünürlüklü Akciğer BT-Temeller: Sık Karşılaşılan Bulgular, Paternler, Hastalık- lar ve Ayırıcı Tanı, çev: Çetin Atasoy, Dünya tıp kitapevi 2015; 75-7.
  • Remy-Jardin M, Remy J, Giraud F, WattineL, Gosselin B. Computed tomography assessment of ground-glass opa- city: semiology and significance. J Thorac Imaging 1993; 8:249-64.
  • Stern EJ, Webb WR. Dynamic imaging of lung morpho- logy with ultrafast high-resolution computed tomography. J ThoracImaging 1993:8:273-82.
  • Webb WR, Stern EJ, Kanth N, Gamsu G. Dynamic pul- monary CT: findings in healthy adult men. Radiology 1993:186:117-24.
  • Kligerman SJ, Henry T, Lin CT, Franks TJ, Galvin JR. Mo- saic attenuation: etiology, methods of differentiation, and pitfalls. Radiographics 2015;35(5): 1360-80.
  • Gotway MB, Reddy GP, Webb WR, Elicker BM, LeungJ W. High-resolution CT of thelung: patterns of disease and dif- ferential diagnoses. Radiol Clin North Am 2005;43:513-22.
  • Ng CS, Wells AU, Padley SP. A CT sign of chronic pulmo- nary arterial hypertension: the ratio of main pulmonary artery to aortic diameter. J Thorac Imaging 1999;14:270–8.
  • Devaraj A, Wells AU, Meister MG, Corte TJ, Wort SJ, Han- sellDM. Detection of pulmonary hypertension with multi- detector CT and echocardiography alone and in combinati- on Radiology 2010;254:609–16.
  • Tan RT, Kuzo R, Goodman LR, Siegel R, Haasler GB,Pres- berg KW. Utility of CT scan evaluation for predicting pul- monary hypertension in patients with parenchymal lung disease. Medical College of Wisconsin Lung Transplant Group. Chest 1998;113:1250–6.
There are 15 citations in total.

Details

Primary Language Turkish
Journal Section Original Article
Authors

Fatma Durmaz This is me

Mesut Özgökçe This is me

Aysel Sünnetçioğlu This is me

İlyas Dündar This is me

Cemil Göya This is me

Publication Date December 1, 2020
Published in Issue Year 2020 Volume: 30 Issue: 4

Cite

Vancouver Durmaz F, Özgökçe M, Sünnetçioğlu A, Dündar İ, Göya C. Akciğer Bilgisayarlı Tomografisinde Sık Görülen Mozaik Perfüzyon Etyolojisinde Radyolojik İpuçları. Genel Tıp Derg. 2020;30(4):218-23.

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