Abstract
Amaç: İnfluenza ve pnömokok enfeksiyonları renal transplantasyonlu hasta grubunda önemli morbiditelere neden olmaktadır. Ülkemizde renal transplant hastalarının influenza ve pnömokok aşısı ile aşılanma oranları ve bunu etkileyebilecek faktörlerin araştırılması amaçlanmıştır.Gereç ve Yöntem: Çalışmaya Sağlık Bilimleri Üniversitesi Konya Eğitim ve Araştırma Hastanesi nefroloji polikliniğinde takipli 197 renal transplant hastası dahil edildi. Hastalara influenza ve pnömokok aşısı ile ilgili anket dolduruldu. Bulgular: Çalışma populasyonumuzda influenza aşı oranı %26.4, pnömokok aşı oranı % 2.5 idi. Aşı yaptırmamanın başlıca sebebi hastalara aşı yaptırması konusunda tavsiyede bulunulmaması idi influenza aşısı için %45.6 iken pnömokok aşısında %95.4’ü buluyordu . Hastaların % 12.6’sı influenza aşının etkisine inanmadığı için, % 7.6’sı yan etkiden korktuğu için ve %7.1’i influenza enfeksiyonu geçirmediği için aşılanmamışlardı. Aşı yaptıran hastalarda kimin tavsiyesi ile yaptırdığı sorulduğunda en sık nakil merkezi veya takip eden nefroloji doktorlarının tavsiyesi ile aşılandıkları belirlendi influenza aşısı için bu oran % 84.6 ve pnömokok aşısı için %100 .Sonuç: Görüş birliği ve güçlü tavsiyelere rağmen renal transplant alıcılarında aşılanma oranları hedeflerin altındadır. Bu hassas hasta grubunda aşı ile önlenebilen hastalıklarla ilgili aşı farkındalığını ve aşılanma oranlarını artırabilmek için çaba gösterilmelidir
References
- A pathway to leadership for adult immunization: recom- mendations of the National Vaccine Advisory Committee: approved by the National Vaccine Advisory Committee on June 14, 2011. Public Health Rep 2012;127 Suppl 1:1-42.
- Lu P, Bridges CB, Euler GL, et al. Influenza vaccination of recommended adult populations, U.S., 1989-2005. Vaccine 2008;26:1786-93.
- Kumar D, Blumberg EA, Danziger-Isakov L, et al. Inf- luenza vaccination in the organ transplant recipient: re- view and summary recommendations. Am J Transplant 2011;11:2020-30.
- Gunawansa N, Rathore R, Sharma A et al. Vaccination pra- ctices in End Stage Renal Failure and Renal Transplanta- tion; Review of current guidelines and recommendations. World J Transplant 2018;8:68-74.
- Linnemann CC, Jr., First MR. Risk of pneumococcal infec- tions in renal transplant patients. JAMA 1979;241:2619-21.
- Taylan M. Pneumococcal vaccines. Güncel Göğüs Hastalık- ları Serisi 2014;2:98-105.
- Danziger-Isakov L, Kumar D. Vaccination in solid organ transplantation. Am J Transplant 2013;13 Suppl 4:311-7.
- Levey AS, Stevens LA, Schmid CH et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009;150:604-12.
- Türkiye’de Renal Replasman Tedavilerinin Güncel Duru- mu: Türk Nefroloji Derneği Kayıt Sistemi 2016 yılı Özet Raporu Turk Neph Dial Transpl 2018; 27:133-9.
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- Esin Şenol, Alpay Azap, Ayşe Erbay, Sema Alp-Çavuş, Resul Karakuş, Ali Acar Erişkin Bağışıklamasının Hede- findeki Aşılardan Biri Olarak Pnömokok Aşısı: Türk Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Derneği Erişkin Bağışıklaması Çalışma Grubu Uzlaşı Raporu Klimik Der- gisi 2018; 31: 2-18.
- Weaver M, Krieger J, Castorina J et al. Cost-effectiveness of combined outreach for the pneumococcal and influenza vaccines. Arch Intern Med 2001;161:111-20.
- Akin L, Kaya M, Altinel S et al. Cost of pneumococcal infe- ctions and cost-effectiveness analysis of pneumococcal vac- cination at risk adults and elderly in Turkey. Hum Vaccin 2011;7:441-50.
- Necmi Eren. Kocaeli ilinde hemodiyaliz hastalarındaki pnömokok aşılanma farkındalığı. 20. Ulusal Hipertansiyon ve Böbrek Hastalıkları Kongresi 9-13 Mayıs-2018, Bafra, KKTC Sözlü sunum.
- Satman I, Akalin S, Cakir B et al. The effect of physicians' awareness on influenza and pneumococcal vaccination ra- tes and correlates of vaccination in patients with diabetes in Turkey: an epidemiological Study "diaVAX". Hum Vaccin Immunother. 2013;9:2618-26.
- http://www.tihud.org.tr/main/content?ref=2&child=179 erişim tarihi 01.09.2018.
- Harris K, Baggs J, Davis RL, et al. Influenza vaccination co- verage among adult solid organ transplant recipients at th- ree health maintenance organizations, 1995-2005. Vaccine 2009;27:2335-41.
- Chong HJ, Kim HK, Lee MH et al. Influenza vaccine accep- tance and health beliefs among Korean kidney transplant patients. Psychol Health Med. 2018; 30:1-12.
- Chesi C, Günther M, Huzly D et al. Immunization of liver and renal transplant recipients: a seroepidemiological and sociodemographic survey. Transpl Infect Dis 2009;11:507- 12.
- Lee DH, Boyle SM, Malat G,et al. Low rates of vaccination in listed kidney transplant candidates. Transpl Infect Dis. 2016;18:155-9.
Abstract
Objective: Influenza and pneumococcal infections cause significant morbidity in renal transplant patients. The aim of this study was to investigate the rates of influenza and pneumococcal vaccination in our country and the factors that may affect it.Material and Methods: The study included 197 renal transplant patients who were followed up at the nephrology outpatient clinic of Konya Education and Research Hospital. The questionnaire on influenza and pneumococcal vaccination was completed. Results: In our study population, the rate of influenza vaccine was 26.4% and pneumococcal vaccine rate was 2.5%. The main reason for not taking the vaccination was the lack of advice on vaccination to the patients 45.6% for the influenza vaccine and 95.4% for the pneumococcal vaccine . Because 12.6% of patients did not believe the effect of influenza vaccine, 7.6% were afraid of side effects and 7.1% were not vaccinated because they did not have an influenza infection. When asked who made the vaccination with a recommendation, it was determined that they were most frequently vaccinated with the advice of the transplant center or the following nephrologists influenza vaccine 84.6 and 100% for pneumococcal vaccine .Conclusion: Despite consensus and strong recommendations, vaccination rates in renal transplant recipients are lower than targets. Efforts should be made to increase vaccine awareness and vaccination rates for vaccine-preventable diseases in this sensitive patient group
References
- A pathway to leadership for adult immunization: recom- mendations of the National Vaccine Advisory Committee: approved by the National Vaccine Advisory Committee on June 14, 2011. Public Health Rep 2012;127 Suppl 1:1-42.
- Lu P, Bridges CB, Euler GL, et al. Influenza vaccination of recommended adult populations, U.S., 1989-2005. Vaccine 2008;26:1786-93.
- Kumar D, Blumberg EA, Danziger-Isakov L, et al. Inf- luenza vaccination in the organ transplant recipient: re- view and summary recommendations. Am J Transplant 2011;11:2020-30.
- Gunawansa N, Rathore R, Sharma A et al. Vaccination pra- ctices in End Stage Renal Failure and Renal Transplanta- tion; Review of current guidelines and recommendations. World J Transplant 2018;8:68-74.
- Linnemann CC, Jr., First MR. Risk of pneumococcal infec- tions in renal transplant patients. JAMA 1979;241:2619-21.
- Taylan M. Pneumococcal vaccines. Güncel Göğüs Hastalık- ları Serisi 2014;2:98-105.
- Danziger-Isakov L, Kumar D. Vaccination in solid organ transplantation. Am J Transplant 2013;13 Suppl 4:311-7.
- Levey AS, Stevens LA, Schmid CH et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009;150:604-12.
- Türkiye’de Renal Replasman Tedavilerinin Güncel Duru- mu: Türk Nefroloji Derneği Kayıt Sistemi 2016 yılı Özet Raporu Turk Neph Dial Transpl 2018; 27:133-9.
- Erişkin Bağışıklama Rehberi. Turkiye Enfeksiyon Hastalık- ları ve Klinik Mikrobiyoloji Uzmanlık Dernegi, http://ek- mud.org.tr/wp-content/uploads/EriskinBagisiklamaReh- beri-web.pdf. Istanbul, 2016.
- Esin Şenol, Alpay Azap, Ayşe Erbay, Sema Alp-Çavuş, Resul Karakuş, Ali Acar Erişkin Bağışıklamasının Hede- findeki Aşılardan Biri Olarak Pnömokok Aşısı: Türk Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Derneği Erişkin Bağışıklaması Çalışma Grubu Uzlaşı Raporu Klimik Der- gisi 2018; 31: 2-18.
- Weaver M, Krieger J, Castorina J et al. Cost-effectiveness of combined outreach for the pneumococcal and influenza vaccines. Arch Intern Med 2001;161:111-20.
- Akin L, Kaya M, Altinel S et al. Cost of pneumococcal infe- ctions and cost-effectiveness analysis of pneumococcal vac- cination at risk adults and elderly in Turkey. Hum Vaccin 2011;7:441-50.
- Necmi Eren. Kocaeli ilinde hemodiyaliz hastalarındaki pnömokok aşılanma farkındalığı. 20. Ulusal Hipertansiyon ve Böbrek Hastalıkları Kongresi 9-13 Mayıs-2018, Bafra, KKTC Sözlü sunum.
- Satman I, Akalin S, Cakir B et al. The effect of physicians' awareness on influenza and pneumococcal vaccination ra- tes and correlates of vaccination in patients with diabetes in Turkey: an epidemiological Study "diaVAX". Hum Vaccin Immunother. 2013;9:2618-26.
- http://www.tihud.org.tr/main/content?ref=2&child=179 erişim tarihi 01.09.2018.
- Harris K, Baggs J, Davis RL, et al. Influenza vaccination co- verage among adult solid organ transplant recipients at th- ree health maintenance organizations, 1995-2005. Vaccine 2009;27:2335-41.
- Chong HJ, Kim HK, Lee MH et al. Influenza vaccine accep- tance and health beliefs among Korean kidney transplant patients. Psychol Health Med. 2018; 30:1-12.
- Chesi C, Günther M, Huzly D et al. Immunization of liver and renal transplant recipients: a seroepidemiological and sociodemographic survey. Transpl Infect Dis 2009;11:507- 12.
- Lee DH, Boyle SM, Malat G,et al. Low rates of vaccination in listed kidney transplant candidates. Transpl Infect Dis. 2016;18:155-9.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Original Article |
| Authors | |
| Publication Date | January 1, 2019 |
| Published in Issue | Year 2019 Volume: 29 Issue: 1 |
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