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Hepatosellüler karsinomda radyolojik algoritma ve görüntüleme yöntemleri

Year 2014, Volume: 24 Issue: 4, 162 - 167, 01.01.2014

Abstract

Radyolojik görüntülemenin amacı hepatosellüler karsinomu erken evrede tespit etmektir. Bunun amacı lezyonu küratif tedavi evre- sinde yakalayabilmektir. Son yıllarda özellikle küçük karsinomların erken tespit edilebilmesi için fazlaca çaba sarf edilmektedir. Bu derlemenin amacı hepatosellüler karsinomların tespiti ve tanımlanmasında ultrasonografi, bilgisayarlı tomografi, manyetik rezonans görüntüleme, radyonüklid görüntüleme, pozitron emisyon tomografi ve dijital subtraksiyon anjiografi gibi invaziv olmayan görüntü- leme yöntemlerinin etkinliğini belirlemektir

References

  • Bruix J, Sherma M. AASLD Practice Guideline. Management of hepatocellular carcinoma: an update. Hepatology 2010;1-35.
  • Kudo M. The 2008 Okuda lecture: Management of hepatocellu- lar carcinoma: From surveillance to molecular targeted therapy. J Gastroenterol Hepatol 2010;25:439-52.
  • Shapiro RS, Wagreich J, Parsons RB, et al. Tissue harmonic im- aging sonography: evaluation of image quality compared with conventional sonography. AJR Am J Roentgenol 1998;171:1203–6.
  • Teefey SA, Hildeboldt CC, Dehdashti F, et al. Detection of pri- mary hepatic malignancy in liver transplant candidates: prospec- tive comparison of CT, MR imaging, US, and PET. Radiology 2003;226:533-42.
  • Bruix J, Sherman M. Management of hepatocellular carcinoma. Hepatology 2005;42:1208-36.
  • Saar B, Kellner-Weldon F. Radiological Diagnosis of Hepatocellu- lar Carcinoma. Liver Int 2008;28:189-99.
  • Teefey SA, Stephens DE, Weiland DH. Calcification in hapatocel- luler carcinoma: not always indicator of fibrolamellar histology. AJR 1988;151:717-20.
  • Wilson SR, Withers CE. The liver. In: Rumack CM, Wilson SR, Charboneau JW,editors. Diagnostic ultrasound. 3rd ed. St Louis (MO): CV Mosby Co 2005;77–146.
  • Oliver JH, Baron RL. Helical biphasic contrast enhanced CT of the liver: technique, indications, interpretations and pitfalls. Radiolo- gy 1996;201:1-9.
  • Franca AV, Elias Junior J, Lima BL, et al. Diagnosis, staging and treatment of hepatocellular carcinoma. Braz J Med Biol Res 2004;37:1689-705.
  • Gomaa AI, Khan SA, Leen EL, et al. Diagnosis of hepatocellular carcinoma. World J Gastroenterol 2009;15:1301-14.
  • Lencioni R, Piscaglia F, Bolondi L. Contrast-enhanced ultra- sound in the diagnosis of hepatocellular carcinoma. J Hepatol 2008;48:848-57.
  • Gheorghe L, Iacob S, Iacob R, et al. Real time elastography—a non-invasive diagnostic method of small hepatocellular carcino- ma in cirrhosis. J Gastrointestin Liver Dis 2009;18:439–46.
  • Caturelli E, Pompili M, Bartolucci F, et al. Hemangioma-like le- sions in cirrhotic liver disease: diagnostic evaluation in patients. Radiology 2001;220:337–42.
  • Ollet MD, Jeffry RB Jr, Nino Murcia M, et al. Dual phase helical ct of the liver: Value of arterial scans in the detection of small (<1.5cm) malignant hepatic neoplasms. AJR Am J Roentgenol 1995;164:879-84.
  • Forner A, Vilana R, Ayuso C, et al. Diagnosis of hepatic nodules 20 mm or smaller in cirrhosis: Prospective validation of the noninva- sive diagnostic criteria for hepatocellular carcinoma. Hepatology 2008;47:97–104.
  • Iannaccone R, Piacentini F,Murakami T, et al. Hepatocellular car- cinoma in patients with nonalcoholic fatty liver disease: helical CT and MR imaging findings with clinical- pathologic comparison. Radiology 2007;243:423–30.
  • Collier J, Sherman M. Screening for hepatocellular carcinoma. Hepatology 1998;27:273-8.
  • Brancatelli G, Federle MP, Grazioli L, Carr BI. Hepatocellular car- cinoma in noncirrhotic liver: CT, clinical, and pathologic findings in 39 U.S. residents. Radiology 2002;222:89–94.
  • Mitsuzaki K, Yamashita Y, Ogata I, et al. Multiple-phase helical CT of the liver for detecting small hepatomas in patients with liver cirrhosis: contrast-injection koprotocol and optimal timing. AJR Am J Roentgenol 1996;167:753–7.
  • Zhao H, Yao JL, Wang Y, Zhou KR. Detection of small hepatocel- lular carcinoma: comparison of dynamic enhancement magnetic resonance imaging and multiphase multirow-detector helical CT scanning. World J Gastroenterol 2007;13:1252-6.
  • Peterson MS, Baron RL. Radiologic diagnosis of hepatocellular carcinoma. Clin Liver Dis 2001;5:123–44.
  • Ikeda K, Saitoh S, Koida I,et al. Imaging diagnosis of small hepato- cellular carcinoma. Hepatology 1994;20:82-7.
  • Willatt MJ, Hussain KH, Adusumilli S, et al. MR imaging of hepa- tocellular carcinoma in the cirrhotic liver: challenges and contro- versies. Radiology 2008;247:311–30.
  • Nasu K, Kuroki Y, Tsukamoto T, et al. Diffusion-weighted imaging of surgically resected hepatocellular carcinoma: Imaging charac- teristics and relationship among signal intensity, apparent diffu- sion coefficient, and histopathologic grade. AJR Am J Roentgeno 2009;193:438-44.
  • Kitao A, Zen Y, Matsui O, et al. Hepatocarcinogenesis: multistep changes of drainage vessels at CT during arterial portography and hepatic arteriography radiologic-pathologic correlation. Radiolo- gy 2009;252:605–14.
  • Kim T, Baron RL, Nalesnik MA. Infarcted regenerative nodules in cirrhosis: CTand MR imaging findings with pathologic correla- tion. AJR Am J Roentgenol 2000;175:1121–5.
  • Mc Cless EC, Gedgahder Mc Claas RD. Screening for diffuse and focal liver disease: the case for hepatic scintigraphy. J Clin Ultra- sound 1984;12:75-81.
  • Vilgrain V, Boulos L, Vullierme M.P, et al. Imaging of atypical hemangiomas of the liver with pathologic correlation radiograph- ics. 2000;20:379-97.
  • Khan MA, Coms CS, Brunt EM, et al. Positron emission tomog- raphy scanning in the evaluation of hepatocellular carcinoma. J Hepatol 2000;32:792–7.
  • Trojan J, Schroeder O, Raedle J, et al. Fluorine -18 FDG positron emission tomography for imaging of hepatocellular carcinoma. Am J Gastroenterol 1999;94:3314–9.
  • Ho CL, Chen S, Yeung DW, Cheng TK. Dual tracer PET/CT im- aging in evaluation of metastatic hepatocellular carcinoma. J Nucl Med 2007;48:902–9.
  • Takayasu K, Shima Y, Muramatsu Y et al. Angiography of small hepatocellular carcinoma. Analysis of 105 resected tumors. AJR 1986;147:525-9.

Radiological algorithm and imaging modalities in hepatocellular carcinoma

Year 2014, Volume: 24 Issue: 4, 162 - 167, 01.01.2014

Abstract

The purpose of diagnostic imaging is to detect HCC at an early stage, when curative options are available. In recent years, there have been many efforts to improve early detection of small HCC. The purpose of this review is to describe the pertinent findings of HCCs in non-invasive, diagnostic imaging, including ultrasound, computed tomography, magnetic resonance, radionuclide scanning, positron emission tomography and digital subtraction angiography imaging techniques

References

  • Bruix J, Sherma M. AASLD Practice Guideline. Management of hepatocellular carcinoma: an update. Hepatology 2010;1-35.
  • Kudo M. The 2008 Okuda lecture: Management of hepatocellu- lar carcinoma: From surveillance to molecular targeted therapy. J Gastroenterol Hepatol 2010;25:439-52.
  • Shapiro RS, Wagreich J, Parsons RB, et al. Tissue harmonic im- aging sonography: evaluation of image quality compared with conventional sonography. AJR Am J Roentgenol 1998;171:1203–6.
  • Teefey SA, Hildeboldt CC, Dehdashti F, et al. Detection of pri- mary hepatic malignancy in liver transplant candidates: prospec- tive comparison of CT, MR imaging, US, and PET. Radiology 2003;226:533-42.
  • Bruix J, Sherman M. Management of hepatocellular carcinoma. Hepatology 2005;42:1208-36.
  • Saar B, Kellner-Weldon F. Radiological Diagnosis of Hepatocellu- lar Carcinoma. Liver Int 2008;28:189-99.
  • Teefey SA, Stephens DE, Weiland DH. Calcification in hapatocel- luler carcinoma: not always indicator of fibrolamellar histology. AJR 1988;151:717-20.
  • Wilson SR, Withers CE. The liver. In: Rumack CM, Wilson SR, Charboneau JW,editors. Diagnostic ultrasound. 3rd ed. St Louis (MO): CV Mosby Co 2005;77–146.
  • Oliver JH, Baron RL. Helical biphasic contrast enhanced CT of the liver: technique, indications, interpretations and pitfalls. Radiolo- gy 1996;201:1-9.
  • Franca AV, Elias Junior J, Lima BL, et al. Diagnosis, staging and treatment of hepatocellular carcinoma. Braz J Med Biol Res 2004;37:1689-705.
  • Gomaa AI, Khan SA, Leen EL, et al. Diagnosis of hepatocellular carcinoma. World J Gastroenterol 2009;15:1301-14.
  • Lencioni R, Piscaglia F, Bolondi L. Contrast-enhanced ultra- sound in the diagnosis of hepatocellular carcinoma. J Hepatol 2008;48:848-57.
  • Gheorghe L, Iacob S, Iacob R, et al. Real time elastography—a non-invasive diagnostic method of small hepatocellular carcino- ma in cirrhosis. J Gastrointestin Liver Dis 2009;18:439–46.
  • Caturelli E, Pompili M, Bartolucci F, et al. Hemangioma-like le- sions in cirrhotic liver disease: diagnostic evaluation in patients. Radiology 2001;220:337–42.
  • Ollet MD, Jeffry RB Jr, Nino Murcia M, et al. Dual phase helical ct of the liver: Value of arterial scans in the detection of small (<1.5cm) malignant hepatic neoplasms. AJR Am J Roentgenol 1995;164:879-84.
  • Forner A, Vilana R, Ayuso C, et al. Diagnosis of hepatic nodules 20 mm or smaller in cirrhosis: Prospective validation of the noninva- sive diagnostic criteria for hepatocellular carcinoma. Hepatology 2008;47:97–104.
  • Iannaccone R, Piacentini F,Murakami T, et al. Hepatocellular car- cinoma in patients with nonalcoholic fatty liver disease: helical CT and MR imaging findings with clinical- pathologic comparison. Radiology 2007;243:423–30.
  • Collier J, Sherman M. Screening for hepatocellular carcinoma. Hepatology 1998;27:273-8.
  • Brancatelli G, Federle MP, Grazioli L, Carr BI. Hepatocellular car- cinoma in noncirrhotic liver: CT, clinical, and pathologic findings in 39 U.S. residents. Radiology 2002;222:89–94.
  • Mitsuzaki K, Yamashita Y, Ogata I, et al. Multiple-phase helical CT of the liver for detecting small hepatomas in patients with liver cirrhosis: contrast-injection koprotocol and optimal timing. AJR Am J Roentgenol 1996;167:753–7.
  • Zhao H, Yao JL, Wang Y, Zhou KR. Detection of small hepatocel- lular carcinoma: comparison of dynamic enhancement magnetic resonance imaging and multiphase multirow-detector helical CT scanning. World J Gastroenterol 2007;13:1252-6.
  • Peterson MS, Baron RL. Radiologic diagnosis of hepatocellular carcinoma. Clin Liver Dis 2001;5:123–44.
  • Ikeda K, Saitoh S, Koida I,et al. Imaging diagnosis of small hepato- cellular carcinoma. Hepatology 1994;20:82-7.
  • Willatt MJ, Hussain KH, Adusumilli S, et al. MR imaging of hepa- tocellular carcinoma in the cirrhotic liver: challenges and contro- versies. Radiology 2008;247:311–30.
  • Nasu K, Kuroki Y, Tsukamoto T, et al. Diffusion-weighted imaging of surgically resected hepatocellular carcinoma: Imaging charac- teristics and relationship among signal intensity, apparent diffu- sion coefficient, and histopathologic grade. AJR Am J Roentgeno 2009;193:438-44.
  • Kitao A, Zen Y, Matsui O, et al. Hepatocarcinogenesis: multistep changes of drainage vessels at CT during arterial portography and hepatic arteriography radiologic-pathologic correlation. Radiolo- gy 2009;252:605–14.
  • Kim T, Baron RL, Nalesnik MA. Infarcted regenerative nodules in cirrhosis: CTand MR imaging findings with pathologic correla- tion. AJR Am J Roentgenol 2000;175:1121–5.
  • Mc Cless EC, Gedgahder Mc Claas RD. Screening for diffuse and focal liver disease: the case for hepatic scintigraphy. J Clin Ultra- sound 1984;12:75-81.
  • Vilgrain V, Boulos L, Vullierme M.P, et al. Imaging of atypical hemangiomas of the liver with pathologic correlation radiograph- ics. 2000;20:379-97.
  • Khan MA, Coms CS, Brunt EM, et al. Positron emission tomog- raphy scanning in the evaluation of hepatocellular carcinoma. J Hepatol 2000;32:792–7.
  • Trojan J, Schroeder O, Raedle J, et al. Fluorine -18 FDG positron emission tomography for imaging of hepatocellular carcinoma. Am J Gastroenterol 1999;94:3314–9.
  • Ho CL, Chen S, Yeung DW, Cheng TK. Dual tracer PET/CT im- aging in evaluation of metastatic hepatocellular carcinoma. J Nucl Med 2007;48:902–9.
  • Takayasu K, Shima Y, Muramatsu Y et al. Angiography of small hepatocellular carcinoma. Analysis of 105 resected tumors. AJR 1986;147:525-9.
There are 33 citations in total.

Details

Primary Language Turkish
Journal Section Collection
Authors

Ahmet Küçükapan This is me

Suat Keskin This is me

Zeynep Keskin This is me

Necdet Poyraz This is me

Publication Date January 1, 2014
Published in Issue Year 2014 Volume: 24 Issue: 4

Cite

Vancouver Küçükapan A, Keskin S, Keskin Z, Poyraz N. Hepatosellüler karsinomda radyolojik algoritma ve görüntüleme yöntemleri. Genel Tıp Derg. 2014;24(4):162-7.

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